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Murcko scaffold

Ring system with 3 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
14
With full pages
2
Scaffold SMILES

O=C(Nc1ccc(C(=O)Nc2ccccc2)s1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(C(=O)Nc2ccccc2)s1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Methyl 5-[(2-methoxyanilino)carbonyl]-4-methyl-2-[(5-methyl-2-furoyl)amino]-3-thiophenecarboxylate chemical structure, C21H20N2O6S, CAS 445029-49-2
Methyl 5-[(2-methoxyanilino)carbonyl]-4-methyl-2-[(5-methyl-2-furoyl)amino]-3-thiophenecarboxylate
CAS 445029-49-2C21H20N2O6S
Methyl 2-(2-furoylamino)-5-[(4-methoxyanilino)carbonyl]-4-methylthiophene-3-carboxylate chemical structure, C20H18N2O6S, CAS 445003-62-3
Methyl 2-(2-furoylamino)-5-[(4-methoxyanilino)carbonyl]-4-methylthiophene-3-carboxylate
CAS 445003-62-3C20H18N2O6S
Isopropyl 4-methyl-2-[(5-methyl-2-furoyl)amino]-5-(2-toluidinocarbonyl)thiophene-3-carboxylate chemical structure, C23H24N2O5S, CAS 445005-75-4
Isopropyl 4-methyl-2-[(5-methyl-2-furoyl)amino]-5-(2-toluidinocarbonyl)thiophene-3-carboxylate
CAS 445005-75-4C23H24N2O5S
Isopropyl 2-(2-furoylamino)-4-methyl-5-(2-toluidinocarbonyl)thiophene-3-carboxylate chemical structure, C22H22N2O5S, CAS 445008-59-3
Isopropyl 2-(2-furoylamino)-4-methyl-5-(2-toluidinocarbonyl)thiophene-3-carboxylate
CAS 445008-59-3C22H22N2O5S
Methyl 2-(furan-2-carbonylamino)-5-[(2-methoxyphenyl)carbamoyl]-4-methylthiophene-3-carboxylate chemical structure, C20H18N2O6S, CAS 333308-34-2
Methyl 2-(furan-2-carbonylamino)-5-[(2-methoxyphenyl)carbamoyl]-4-methylthiophene-3-carboxylate
CAS 333308-34-2C20H18N2O6S
Ethyl 2-(2-furoylamino)-4-methyl-5-{[3-(trifluoromethyl)anilino]carbonyl}-3-thiophenecarboxylate chemical structure, C21H17F3N2O5S, CAS 330216-58-5
Ethyl 2-(2-furoylamino)-4-methyl-5-{[3-(trifluoromethyl)anilino]carbonyl}-3-thiophenecarboxylate
CAS 330216-58-5C21H17F3N2O5S
Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(furan-2-carboxamido)-4-methylthiophene-3-carboxylate chemical structure, C21H20N2O6S, CAS 506416-41-7
Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(furan-2-carboxamido)-4-methylthiophene-3-carboxylate
CAS 506416-41-7C21H20N2O6S
Methyl 5-((4-ethoxyphenyl)carbamoyl)-2-(furan-2-carboxamido)-4-methylthiophene-3-carboxylate chemical structure, C21H20N2O6S, CAS 335410-98-5
Methyl 5-((4-ethoxyphenyl)carbamoyl)-2-(furan-2-carboxamido)-4-methylthiophene-3-carboxylate
CAS 335410-98-5C21H20N2O6S
Ethyl 5-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}-2-(furan-2-amido)-4-methylthiophene-3-carboxylate chemical structure, C21H16ClF3N2O5S, CAS 312696-70-1
Ethyl 5-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}-2-(furan-2-amido)-4-methylthiophene-3-carboxylate
CAS 312696-70-1C21H16ClF3N2O5S
Ethyl 5-{[4-(ethoxycarbonyl)phenyl]carbamoyl}-2-[(furan-2-ylcarbonyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C23H22N2O7S, CAS 312586-52-0
Ethyl 5-{[4-(ethoxycarbonyl)phenyl]carbamoyl}-2-[(furan-2-ylcarbonyl)amino]-4-methylthiophene-3-carboxylate
CAS 312586-52-0C23H22N2O7S
Ethyl 4-methyl-2-[(5-methylfuran-2-carbonyl)amino]-5-[(2-methylphenyl)carbamoyl]thiophene-3-carboxylate chemical structure, C22H22N2O5S, CAS 444999-36-4
Ethyl 4-methyl-2-[(5-methylfuran-2-carbonyl)amino]-5-[(2-methylphenyl)carbamoyl]thiophene-3-carboxylate
CAS 444999-36-4C22H22N2O5S
Ethyl 2-[(furan-2-ylcarbonyl)amino]-5-[(3-methoxyphenyl)carbamoyl]-4-methylthiophene-3-carboxylate chemical structure, C21H20N2O6S, CAS 330952-15-3
Ethyl 2-[(furan-2-ylcarbonyl)amino]-5-[(3-methoxyphenyl)carbamoyl]-4-methylthiophene-3-carboxylate
CAS 330952-15-3C21H20N2O6S
Ethyl 2-(furan-2-carboxamido)-4-methyl-5-(o-tolylcarbamoyl)thiophene-3-carboxylate chemical structure, C21H20N2O5S, CAS 312586-50-8
Ethyl 2-(furan-2-carboxamido)-4-methyl-5-(o-tolylcarbamoyl)thiophene-3-carboxylate
CAS 312586-50-8C21H20N2O5S
Propan-2-yl 4-methyl-2-[(5-methylfuran-2-carbonyl)amino]-5-(phenylcarbamoyl)thiophene-3-carboxylate chemical structure, C22H22N2O5S, CAS 444998-99-6
Propan-2-yl 4-methyl-2-[(5-methylfuran-2-carbonyl)amino]-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS 444998-99-6C22H22N2O5S