Murcko scaffold
4-(Benzyloxy)piperidine scaffold
132 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 132
- With full pages
- 10
Scaffold SMILES
c1ccc(COC2CCNCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 132 chemicals
4-(Benzyloxy)piperidine
CAS 76716-51-3C12H17NO
4-Benzyloxy TEMPO
CAS 31645-22-4C16H25NO2
tert-Butyl 4-(benzyloxy)piperidine-1-carboxylate
CAS 159557-47-8C17H25NO3
![4-[(3,4,5-Trimethoxyphenyl)methoxy]piperidine chemical structure, C15H23NO4, CAS 81151-40-8](/s/UWOVDQAMRNZVIM-UHFFFAOYSA-N.svg)
4-[(3,4,5-Trimethoxyphenyl)methoxy]piperidine
CAS 81151-40-8C15H23NO4
1-Ethoxycarbonyl-4-benzyloxypiperidine
CAS 81151-69-1C15H21NO3
4-(Benzyloxy)piperidine hydrochloride
CAS 81151-68-0C12H18ClNO
4-((4-Chlorobenzyl)oxy)piperidine hydrochloride
CAS 86810-95-9C12H17Cl2NO
![4-[(3,4-Dichlorophenyl)methoxy]piperidine chemical structure, C12H15Cl2NO, CAS 104634-82-4](/s/GOUZDPRTQFIDBF-UHFFFAOYSA-N.svg)
4-[(3,4-Dichlorophenyl)methoxy]piperidine
CAS 104634-82-4C12H15Cl2NO
4-((3,4-Dichlorobenzyl)oxy)piperidine hydrochloride
CAS 86810-96-0C12H16Cl3NO
![4-[(4-Propan-2-ylphenyl)methoxy]piperidine chemical structure, C15H23NO, CAS 86811-07-6](/s/LUMHVLIJJILBTG-UHFFFAOYSA-N.svg)
4-[(4-Propan-2-ylphenyl)methoxy]piperidine
CAS 86811-07-6C15H23NO
![4-[(4-Bromophenyl)methoxy]piperidine chemical structure, C12H16BrNO, CAS 104634-88-0](/s/FYQRZXJLGKAUMO-UHFFFAOYSA-N.svg)
4-[(4-Bromophenyl)methoxy]piperidine
CAS 104634-88-0C12H16BrNO
![4-[(4-Bromobenzyl)oxy]piperidine hydrochloride chemical structure, C12H17BrClNO, CAS 86811-34-9](/s/SMVMEMRCOQHSDN-UHFFFAOYSA-N.svg)
4-[(4-Bromobenzyl)oxy]piperidine hydrochloride
CAS 86811-34-9C12H17BrClNO
![1-{4-Ethynyl-4-[(2-fluorophenyl)methoxy]piperidin-1-yl}ethan-1-one chemical structure, C16H18FNO2, CAS 88161-97-1](/s/DMMUHXISCJAIFY-UHFFFAOYSA-N.svg)
1-{4-Ethynyl-4-[(2-fluorophenyl)methoxy]piperidin-1-yl}ethan-1-one
CAS 88161-97-1C16H18FNO2
![1-{4-[(2-Fluorophenyl)methoxy]piperidin-4-yl}ethan-1-one chemical structure, C14H18FNO2, CAS 88144-27-8](/s/DOYBYLNPQQYGHR-UHFFFAOYSA-N.svg)
1-{4-[(2-Fluorophenyl)methoxy]piperidin-4-yl}ethan-1-one
CAS 88144-27-8C14H18FNO2
4-(1-Oxoethyl)-4-(2-fluorophenylmethoxy)piperidine oxalate
CAS 88144-28-9C16H20FNO6
![1-{4-[(2,5-Difluorophenyl)methoxy]-4-ethynylpiperidin-1-yl}ethan-1-one chemical structure, C16H17F2NO2, CAS 88144-60-9](/s/AXRBONGFYDBEKK-UHFFFAOYSA-N.svg)
1-{4-[(2,5-Difluorophenyl)methoxy]-4-ethynylpiperidin-1-yl}ethan-1-one
CAS 88144-60-9C16H17F2NO2
![4-[(2-Methoxyphenyl)methoxy]piperidine chemical structure, C13H19NO2, CAS 86928-12-3](/s/FTYCCQKEFAMLOF-UHFFFAOYSA-N.svg)
4-[(2-Methoxyphenyl)methoxy]piperidine
CAS 86928-12-3C13H19NO2
![4-[(2-Methoxyphenyl)methoxy]piperidine hydrochloride chemical structure, C13H20ClNO2, CAS 81151-57-7](/s/BNSIMWGTNZTGAM-UHFFFAOYSA-N.svg)
4-[(2-Methoxyphenyl)methoxy]piperidine hydrochloride
CAS 81151-57-7C13H20ClNO2
![4-[(4-Fluorophenyl)methoxy]piperidine chemical structure, C12H16FNO, CAS 81151-35-1](/s/HKWRVHLLZSIWAR-UHFFFAOYSA-N.svg)
4-[(4-Fluorophenyl)methoxy]piperidine
CAS 81151-35-1C12H16FNO
![4-[(2-Methylphenyl)methoxy]piperidine chemical structure, C13H19NO, CAS 81151-51-1](/s/NJFYIPAFKCBDPW-UHFFFAOYSA-N.svg)
4-[(2-Methylphenyl)methoxy]piperidine
CAS 81151-51-1C13H19NO
![4-[(4-Methylphenyl)methoxy]piperidine chemical structure, C13H19NO, CAS 81151-53-3](/s/YBNAVJMCEICEHT-UHFFFAOYSA-N.svg)
4-[(4-Methylphenyl)methoxy]piperidine
CAS 81151-53-3C13H19NO
![4-[[3-(Trifluoromethyl)phenyl]methoxy]piperidine chemical structure, C13H16F3NO, CAS 81151-55-5](/s/MPARZOFPWOKMBF-UHFFFAOYSA-N.svg)
4-[[3-(Trifluoromethyl)phenyl]methoxy]piperidine
CAS 81151-55-5C13H16F3NO
![4-[(4-Methoxyphenyl)methoxy]piperidine chemical structure, C13H19NO2, CAS 1220028-57-8](/s/OUAFKQJFEYUOIG-UHFFFAOYSA-N.svg)
4-[(4-Methoxyphenyl)methoxy]piperidine
CAS 1220028-57-8C13H19NO2
4-(Benzyloxy)-2,2,6,6-tetramethylpiperidine
CAS 26275-91-2C16H25NO
- 4-(4-Trifluoromethylbenzyloxy)piperidine308386-14-3C13H16F3NO
- 4-((4-(Trifluoromethoxy)benzyl)oxy)piperidine681482-45-1C13H16F3NO2
- tert-Butyl 4-(4-(trifluoromethoxy)benzyloxy)piperidine-1-carboxylate287952-21-0C18H24F3NO4
- 2-(Piperidin-4-yloxymethyl)benzonitrile1098352-41-0C13H16N2O
- 4-(1-Phenylethoxy)piperidine420137-21-9C13H19NO
- 4-[(2-Fluorophenyl)methoxy]piperidine778573-56-1C12H16FNO
- 4-[(3-Chlorophenyl)methoxy]piperidine946759-60-0C12H16ClNO
- 1 suppliers4-((3-Fluorobenzyl)oxy)piperidine946726-24-5C12H16FNO
- 4-Benzyloxy-2,6-diethyl-2,3,6-trimethylpiperidine61777-86-4C19H31NO
- 4-((2-Fluorobenzyl)oxy)piperidine hydrochloride614731-34-9C12H17ClFNO
- tert-Butyl 4-((4-bromophenyl)methoxy)piperidine-1-carboxylate930111-10-7C17H24BrNO3
- 4-{[4-(tert-Butyl)benzyl]oxy}piperidine946681-43-2C16H25NO
- tert-Butyl 4-[(4-formylphenyl)methoxy]piperidine-1-carboxylate1080028-74-5C18H25NO4
- 4-[(3-Bromophenyl)methoxy]piperidine931410-05-8C12H16BrNO
- 4-[(2,4-Dichlorophenyl)methoxy]piperidine1098356-13-8C12H15Cl2NO
- 4-[(3-Fluoro-4-methoxyphenyl)methoxy]piperidine1094533-79-5C13H18FNO2
- 4-(Piperidin-4-yloxymethyl)benzonitrile1098352-07-8C13H16N2O
- 4-[(2-Bromophenyl)methoxy]piperidine1097828-95-9C12H16BrNO
- 4-[(2-Chloro-4-fluorophenyl)methoxy]piperidine1098356-25-2C12H15ClFNO
- 4-[(2,3-Difluorophenyl)methoxy]piperidine1121595-63-8C12H15F2NO
- 4-({[1-(tert-Butoxycarbonyl)piperidin-4-yl]oxy}methyl)benzoic acid934570-52-2C18H25NO5
- tert-Butyl 4-{[4-(aminomethyl)phenyl]methoxy}piperidine-1-carboxylate946409-35-4C18H28N2O3
- tert-Butyl 4-{[4-(hydroxymethyl)phenyl]methoxy}piperidine-1-carboxylate937796-03-7C18H27NO4
- tert-Butyl 4-{[4-(methoxycarbonyl)phenyl]methoxy}piperidine-1-carboxylate1121587-34-5C19H27NO5
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals