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Murcko scaffold

RefChem:382814 scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
35
With full pages
3
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the RefChem:382814 page
Murcko scaffold O=C(CNC(=O)c1ccccc1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

Succinamic acid, 3-benzamido-N-benzyl-, DL- chemical structure, C18H18N2O4, CAS 6461-02-5
Succinamic acid, 3-benzamido-N-benzyl-, DL-
CAS 6461-02-5C18H18N2O4
Glutaramic acid, 4-benzamido-N-benzyl-, DL- chemical structure, C19H20N2O4, CAS 10405-71-7
Glutaramic acid, 4-benzamido-N-benzyl-, DL-
CAS 10405-71-7C19H20N2O4
3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acid chemical structure, C19H19Cl2N5O4, CAS 188804-07-1
3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acid
CAS 188804-07-1C19H19Cl2N5O4
(S)-N-(1-((2-Chlorobenzyl)amino)-3-methyl-1-oxobutan-2-yl)-3-methylbenzamide chemical structure, C20H23ClN2O2, CAS 315233-87-5
(S)-N-(1-((2-Chlorobenzyl)amino)-3-methyl-1-oxobutan-2-yl)-3-methylbenzamide
CAS 315233-87-5C20H23ClN2O2
3-Chloro-N-[2-[(2-methoxyphenyl)methyl-methylamino]-2-oxoethyl]benzamide chemical structure, C18H19ClN2O3, CAS 851287-84-8
3-Chloro-N-[2-[(2-methoxyphenyl)methyl-methylamino]-2-oxoethyl]benzamide
CAS 851287-84-8C18H19ClN2O3
Jnj-63533054 chemical structure, C17H17ClN2O2, CAS 1802326-66-4
Jnj-63533054
CAS 1802326-66-4C17H17ClN2O2
4-Chloro-N-{2-[(2-hydroxy-1-phenylethyl)amino]-2-oxoethyl}benzenecarboxamide chemical structure, C17H17ClN2O3, CAS 338777-58-5
4-Chloro-N-{2-[(2-hydroxy-1-phenylethyl)amino]-2-oxoethyl}benzenecarboxamide
CAS 338777-58-5C17H17ClN2O3
N-(1-Phenylethyl)-2-(phenylformamido)acetamide chemical structure, C17H18N2O2, CAS 104682-44-2
N-(1-Phenylethyl)-2-(phenylformamido)acetamide
CAS 104682-44-2C17H18N2O2
N-[1-[(4-tert-Butylphenyl)methylamino]-4-methylsulfanyl-1-oxobutan-2-yl]benzamide chemical structure, C23H30N2O2S, CAS 1008239-37-9
N-[1-[(4-tert-Butylphenyl)methylamino]-4-methylsulfanyl-1-oxobutan-2-yl]benzamide
CAS 1008239-37-9C23H30N2O2S
Salicylamide, N-((benzylcarbamoyl)methyl)- chemical structure, C16H16N2O3, CAS 56146-00-0
Salicylamide, N-((benzylcarbamoyl)methyl)-
CAS 56146-00-0C16H16N2O3
Benzamide, 2-hydroxy-N-(1-methyl-2-oxo-2-((phenylmethyl)amino)ethyl)- chemical structure, C17H18N2O3, CAS 56146-04-4
Benzamide, 2-hydroxy-N-(1-methyl-2-oxo-2-((phenylmethyl)amino)ethyl)-
CAS 56146-04-4C17H18N2O3
N-(2-(Benzylamino)-2-oxoethyl)-2-fluorobenzamide chemical structure, C16H15FN2O2, CAS 848070-27-9
N-(2-(Benzylamino)-2-oxoethyl)-2-fluorobenzamide
CAS 848070-27-9C16H15FN2O2
RefChem:382814 chemical structure, C16H16N2O2, CAS 3392-91-4
RefChem:382814
CAS 3392-91-4C16H16N2O2
N-[2-[(4-Methoxyphenyl)methylamino]-2-oxoethyl]benzamide chemical structure, C17H18N2O3, CAS 1001589-47-4
N-[2-[(4-Methoxyphenyl)methylamino]-2-oxoethyl]benzamide
CAS 1001589-47-4C17H18N2O3
3-Chloro-N-ethyl-N-[2-[[(4-fluorophenyl)methyl]amino]-2-oxoethyl]benzamide chemical structure, C18H18ClFN2O2, CAS 923770-49-4
3-Chloro-N-ethyl-N-[2-[[(4-fluorophenyl)methyl]amino]-2-oxoethyl]benzamide
CAS 923770-49-4C18H18ClFN2O2
N-{2-Oxo-2-[(2-phenylpropan-2-yl)amino]ethyl}benzamide chemical structure, C18H20N2O2, CAS 104682-02-2
N-{2-Oxo-2-[(2-phenylpropan-2-yl)amino]ethyl}benzamide
CAS 104682-02-2C18H20N2O2
N-{2-[(4-Fluorobenzyl)amino]-2-oxoethyl}benzamide chemical structure, C16H15FN2O2, CAS 863420-86-4
N-{2-[(4-Fluorobenzyl)amino]-2-oxoethyl}benzamide
CAS 863420-86-4C16H15FN2O2
4-({[N-(4-tert-Butylbenzoyl)alanyl]amino}methyl)benzoic acid chemical structure, C22H26N2O4, CAS 1008377-16-9
4-({[N-(4-tert-Butylbenzoyl)alanyl]amino}methyl)benzoic acid
CAS 1008377-16-9C22H26N2O4
N-[1-[[[(3-Chlorophenyl)methyl]amino]carbonyl]-3-(methylthio)propyl]-4-methoxybenzamide chemical structure, C20H23ClN2O3S, CAS 1101136-53-1
N-[1-[[[(3-Chlorophenyl)methyl]amino]carbonyl]-3-(methylthio)propyl]-4-methoxybenzamide
CAS 1101136-53-1C20H23ClN2O3S
N-[3-(Methylthio)-1-[[[[4-(trifluoromethyl)phenyl]methyl]amino]carbonyl]propyl]benzamide chemical structure, C20H21F3N2O2S, CAS 1049728-57-5
N-[3-(Methylthio)-1-[[[[4-(trifluoromethyl)phenyl]methyl]amino]carbonyl]propyl]benzamide
CAS 1049728-57-5C20H21F3N2O2S
N-{1-[(4-Fluorobenzyl)amino]-1-oxopropan-2-yl}benzamide chemical structure, C17H17FN2O2, CAS 1266376-59-3
N-{1-[(4-Fluorobenzyl)amino]-1-oxopropan-2-yl}benzamide
CAS 1266376-59-3C17H17FN2O2
4-Chloro-N-(2-oxo-2-{[(1S)-1-phenylethyl]amino}ethyl)benzamide chemical structure, C17H17ClN2O2, CAS 1802326-67-5
4-Chloro-N-(2-oxo-2-{[(1S)-1-phenylethyl]amino}ethyl)benzamide
CAS 1802326-67-5C17H17ClN2O2
N-{2-[(4-Fluorobenzyl)amino]-2-oxoethyl}-3-methoxybenzamide chemical structure, C17H17FN2O3, CAS 1089463-67-1
N-{2-[(4-Fluorobenzyl)amino]-2-oxoethyl}-3-methoxybenzamide
CAS 1089463-67-1C17H17FN2O3
2-Methyl-N-{2-oxo-2-[(1-phenylethyl)amino]ethyl}benzamide chemical structure, C18H20N2O2, CAS 1043532-19-9
2-Methyl-N-{2-oxo-2-[(1-phenylethyl)amino]ethyl}benzamide
CAS 1043532-19-9C18H20N2O2