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Murcko scaffold

Ring system with 2 rings and 19 atoms

74 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
74
With full pages
26
Scaffold SMILES

O=C(CNc1ccccc1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNc1ccccc1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 74 chemicals

Glycine, N-(4-chloro-2-methylphenyl)-, [(4-ethoxyphenyl)methylene]hydrazide chemical structure, C18H20ClN3O2, CAS 314285-29-5
Glycine, N-(4-chloro-2-methylphenyl)-, [(4-ethoxyphenyl)methylene]hydrazide
CAS 314285-29-5C18H20ClN3O2
N'-(4-Methoxy-3-nitrobenzylidene)-2-(p-tolylamino)acetohydrazide chemical structure, C17H18N4O4
N'-(4-Methoxy-3-nitrobenzylidene)-2-(p-tolylamino)acetohydrazide
C17H18N4O4
Glycine, N-(3-chloro-2-methylphenyl)-, [(4-methylphenyl)methylene]hydrazide chemical structure, C17H18ClN3O, CAS 349460-00-0
Glycine, N-(3-chloro-2-methylphenyl)-, [(4-methylphenyl)methylene]hydrazide
CAS 349460-00-0C17H18ClN3O
Glycine, N-(4-ethoxyphenyl)-, [(3,4,5-trimethoxyphenyl)methylene]hydrazide chemical structure, C20H25N3O5, CAS 346725-55-1
Glycine, N-(4-ethoxyphenyl)-, [(3,4,5-trimethoxyphenyl)methylene]hydrazide
CAS 346725-55-1C20H25N3O5
N'-(5-Bromo-2-hydroxy-3-iodobenzylidene)-2-(p-tolylamino)acetohydrazide chemical structure, C16H15BrIN3O2, CAS 418782-02-2
N'-(5-Bromo-2-hydroxy-3-iodobenzylidene)-2-(p-tolylamino)acetohydrazide
CAS 418782-02-2C16H15BrIN3O2
N'-(4-Hydroxy-3-iodobenzylidene)-2-(p-tolylamino)acetohydrazide chemical structure, C16H16IN3O2, CAS 329916-35-0
N'-(4-Hydroxy-3-iodobenzylidene)-2-(p-tolylamino)acetohydrazide
CAS 329916-35-0C16H16IN3O2
N'-(2-Hydroxy-5-iodobenzylidene)-2-(p-tolylamino)acetohydrazide chemical structure, C16H16IN3O2, CAS 350042-10-3
N'-(2-Hydroxy-5-iodobenzylidene)-2-(p-tolylamino)acetohydrazide
CAS 350042-10-3C16H16IN3O2
Glycine, N-(2,4-dibromophenyl)-, [(4-hydroxyphenyl)methylene]hydrazide chemical structure, C15H13Br2N3O2, CAS 318261-50-6
Glycine, N-(2,4-dibromophenyl)-, [(4-hydroxyphenyl)methylene]hydrazide
CAS 318261-50-6C15H13Br2N3O2
N-[(2-Chloro-5-nitrophenyl)methylideneamino]-2-(2,3-dimethyl-N-methylsulfonylanilino)acetamide chemical structure, C18H19ClN4O5S, CAS 5751-05-3
N-[(2-Chloro-5-nitrophenyl)methylideneamino]-2-(2,3-dimethyl-N-methylsulfonylanilino)acetamide
CAS 5751-05-3C18H19ClN4O5S
Glycine, N-(3,5-dibromo-4-methylphenyl)-, [(2-hydroxy-5-methoxyphenyl)methylene]hydrazide chemical structure, C17H17Br2N3O3, CAS 325970-72-7
Glycine, N-(3,5-dibromo-4-methylphenyl)-, [(2-hydroxy-5-methoxyphenyl)methylene]hydrazide
CAS 325970-72-7C17H17Br2N3O3
N'-(3,5-Dibromo-4-hydroxybenzylidene)-2-((2-methoxyphenyl)amino)acetohydrazide chemical structure, C16H15Br2N3O3, CAS 326001-50-7
N'-(3,5-Dibromo-4-hydroxybenzylidene)-2-((2-methoxyphenyl)amino)acetohydrazide
CAS 326001-50-7C16H15Br2N3O3
N'-(3-Bromo-4,5-dimethoxybenzylidene)-2-(o-tolylamino)acetohydrazide chemical structure, C18H20BrN3O3, CAS 328577-16-8
N'-(3-Bromo-4,5-dimethoxybenzylidene)-2-(o-tolylamino)acetohydrazide
CAS 328577-16-8C18H20BrN3O3
Glycine, N-(4-fluorophenyl)-, [(3,4,5-trimethoxyphenyl)methylene]hydrazide chemical structure, C18H20FN3O4, CAS 325997-64-6
Glycine, N-(4-fluorophenyl)-, [(3,4,5-trimethoxyphenyl)methylene]hydrazide
CAS 325997-64-6C18H20FN3O4
2-(2-Methylanilino)-N-[(Z)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide chemical structure, C16H14Br3N3O2, CAS 5536-65-2
2-(2-Methylanilino)-N-[(Z)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide
CAS 5536-65-2C16H14Br3N3O2
2-[2-[(Z)-[[2-(4-Methylanilino)acetyl]hydrazinylidene]methyl]phenoxy]acetic acid chemical structure, C18H19N3O4, CAS 5546-61-2
2-[2-[(Z)-[[2-(4-Methylanilino)acetyl]hydrazinylidene]methyl]phenoxy]acetic acid
CAS 5546-61-2C18H19N3O4
2-(4-Methoxy-N-methylsulfonylanilino)-N-[(E)-(4-propan-2-yloxyphenyl)methylideneamino]propanamide chemical structure, C21H27N3O5S, CAS 5637-46-7
2-(4-Methoxy-N-methylsulfonylanilino)-N-[(E)-(4-propan-2-yloxyphenyl)methylideneamino]propanamide
CAS 5637-46-7C21H27N3O5S
2-(4-Ethoxyanilino)-N'-(3-nitrobenzylidene)acetohydrazide chemical structure, C17H18N4O4, CAS 109092-46-8
2-(4-Ethoxyanilino)-N'-(3-nitrobenzylidene)acetohydrazide
CAS 109092-46-8C17H18N4O4
2-(3-Methylanilino)-N-[(Z)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide chemical structure, C16H14Br3N3O2, CAS 424812-99-7
2-(3-Methylanilino)-N-[(Z)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide
CAS 424812-99-7C16H14Br3N3O2
2-(2,5-Dimethyl-N-methylsulfonylanilino)-N-[(E)-(2-nitrophenyl)methylideneamino]acetamide chemical structure, C18H20N4O5S, CAS 363182-01-8
2-(2,5-Dimethyl-N-methylsulfonylanilino)-N-[(E)-(2-nitrophenyl)methylideneamino]acetamide
CAS 363182-01-8C18H20N4O5S
2-(2,4-Dimethylanilino)-N-[(E)-(2-nitrophenyl)methylideneamino]acetamide chemical structure, C17H18N4O3, CAS 328024-69-7
2-(2,4-Dimethylanilino)-N-[(E)-(2-nitrophenyl)methylideneamino]acetamide
CAS 328024-69-7C17H18N4O3
N-[(E)-(5-Bromo-2,4-dimethoxyphenyl)methylideneamino]-2-(2,4-dimethylanilino)acetamide chemical structure, C19H22BrN3O3, CAS 328024-94-8
N-[(E)-(5-Bromo-2,4-dimethoxyphenyl)methylideneamino]-2-(2,4-dimethylanilino)acetamide
CAS 328024-94-8C19H22BrN3O3
2-(4-Ethoxyanilino)-N'-(1-phenylethylidene)acetohydrazide chemical structure, C18H21N3O2, CAS 303084-70-0
2-(4-Ethoxyanilino)-N'-(1-phenylethylidene)acetohydrazide
CAS 303084-70-0C18H21N3O2
2-(4-Ethoxyanilino)-N'-(1-(4-methylphenyl)ethylidene)acetohydrazide chemical structure, C19H23N3O2, CAS 303083-13-8
2-(4-Ethoxyanilino)-N'-(1-(4-methylphenyl)ethylidene)acetohydrazide
CAS 303083-13-8C19H23N3O2
N'-(4-(Diethylamino)benzylidene)-2-(2-toluidino)acetohydrazide chemical structure, C20H26N4O, CAS 303064-58-6
N'-(4-(Diethylamino)benzylidene)-2-(2-toluidino)acetohydrazide
CAS 303064-58-6C20H26N4O