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Murcko scaffold

1-(Phenylmethyl)-2,5-pyrrolidinedione scaffold

62 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
62
With full pages
6
Scaffold SMILES

O=C1CCC(=O)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenylmethyl)-2,5-pyrrolidinedione page
Murcko scaffold O=C1CCC(=O)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

1-(Phenylmethyl)-2,5-pyrrolidinedione chemical structure, C11H11NO2, CAS 2142-06-5
1-(Phenylmethyl)-2,5-pyrrolidinedione
CAS 2142-06-5C11H11NO2
(±)-N-(2,5-Dioxo-1-(phenylmethyl)-3-pyrrolidinyl)methanesulfonamide chemical structure, C12H14N2O4S, CAS 77693-23-3
(±)-N-(2,5-Dioxo-1-(phenylmethyl)-3-pyrrolidinyl)methanesulfonamide
CAS 77693-23-3C12H14N2O4S
4-Nitrobenzylmaleimide chemical structure, C11H10N2O4, CAS 80301-56-0
4-Nitrobenzylmaleimide
CAS 80301-56-0C11H10N2O4
1-(4-Chlorobenzyl)pyrrolidine-2,5-dione chemical structure, C11H10ClNO2, CAS 91349-11-0
1-(4-Chlorobenzyl)pyrrolidine-2,5-dione
CAS 91349-11-0C11H10ClNO2
1-(2-Nitrobenzyl)pyrrolidine-2,5-dione chemical structure, C11H10N2O4, CAS 39101-27-4
1-(2-Nitrobenzyl)pyrrolidine-2,5-dione
CAS 39101-27-4C11H10N2O4
1-(4-Methoxybenzyl)pyrrolidine-2,5-dione chemical structure, C12H13NO3, CAS 108640-66-0
1-(4-Methoxybenzyl)pyrrolidine-2,5-dione
CAS 108640-66-0C12H13NO3
1-[(2-Aminophenyl)methyl]pyrrolidine-2,5-dione chemical structure, C11H12N2O2, CAS 500896-60-6
1-[(2-Aminophenyl)methyl]pyrrolidine-2,5-dione
CAS 500896-60-6C11H12N2O2
2,5-Pyrrolidinedione, 3-amino-1-(phenylmethyl)- chemical structure, C11H12N2O2, CAS 122996-35-4
2,5-Pyrrolidinedione, 3-amino-1-(phenylmethyl)-
CAS 122996-35-4C11H12N2O2
1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione chemical structure, C11H11NO4, CAS 332040-86-5
1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione
CAS 332040-86-5C11H11NO4
(3R,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione chemical structure, C11H11NO4, CAS 75112-74-2
(3R,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione
CAS 75112-74-2C11H11NO4
(3S,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione chemical structure, C11H11NO4, CAS 187032-53-7
(3S,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione
CAS 187032-53-7C11H11NO4
(3R,4R)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione chemical structure, C11H11NO4, CAS 76045-62-0
(3R,4R)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione
CAS 76045-62-0C11H11NO4
(S)-3-(N-Boc-amino)-N-benzylsuccinimide chemical structure, C16H20N2O4, CAS 706780-18-9
(S)-3-(N-Boc-amino)-N-benzylsuccinimide
CAS 706780-18-9C16H20N2O4
[(3R)-1-Benzyl-2,5-dioxopyrrolidin-3-yl] acetate chemical structure, C13H13NO4, CAS 156150-59-3
[(3R)-1-Benzyl-2,5-dioxopyrrolidin-3-yl] acetate
CAS 156150-59-3C13H13NO4
1-[(2,6-Dichlorophenyl)methyl]pyrrolidine-2,5-dione chemical structure, C11H9Cl2NO2, CAS 108640-69-3
1-[(2,6-Dichlorophenyl)methyl]pyrrolidine-2,5-dione
CAS 108640-69-3C11H9Cl2NO2
3-[(2-Aminoethyl)thio]-1-(4-fluorobenzyl)-2,5-pyrrolidinedione chemical structure, C13H15FN2O2S, CAS 767317-01-1
3-[(2-Aminoethyl)thio]-1-(4-fluorobenzyl)-2,5-pyrrolidinedione
CAS 767317-01-1C13H15FN2O2S
1-Benzyl-3-hydroxy-pyrrolidine-2,5-dione chemical structure, C11H11NO3, CAS 78027-57-3
1-Benzyl-3-hydroxy-pyrrolidine-2,5-dione
CAS 78027-57-3C11H11NO3
1-Benzyl-2,5-dioxo-pyrrolidin-3-yl acetate chemical structure, C13H13NO4, CAS 173353-34-9
1-Benzyl-2,5-dioxo-pyrrolidin-3-yl acetate
CAS 173353-34-9C13H13NO4
(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione chemical structure, C11H11NO3, CAS 101469-91-4
(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione
CAS 101469-91-4C11H11NO3
(3S)-1-[(4-Methoxyphenyl)methyl]-2,5-dioxopyrrolidin-3-yl acetate chemical structure, C14H15NO5, CAS 174874-82-9
(3S)-1-[(4-Methoxyphenyl)methyl]-2,5-dioxopyrrolidin-3-yl acetate
CAS 174874-82-9C14H15NO5
(R)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione chemical structure, C11H11NO3, CAS 165657-63-6
(R)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione
CAS 165657-63-6C11H11NO3
(R)-1-Benzyl-3-aminopyrrole-2,5-dione chemical structure, C11H12N2O2, CAS 400045-28-5
(R)-1-Benzyl-3-aminopyrrole-2,5-dione
CAS 400045-28-5C11H12N2O2
1-(3-Bromobenzyl)pyrrolidine-2,5-dione chemical structure, C11H10BrNO2, CAS 791817-73-7
1-(3-Bromobenzyl)pyrrolidine-2,5-dione
CAS 791817-73-7C11H10BrNO2
1-(2,4-Dimethoxybenzyl)pyrrolidine-2,5-dione chemical structure, C13H15NO4, CAS 684287-65-8
1-(2,4-Dimethoxybenzyl)pyrrolidine-2,5-dione
CAS 684287-65-8C13H15NO4