Murcko scaffold
2-Phenylpyrrole scaffold
882 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 882
- With full pages
- 49
Scaffold SMILES
c1ccc(-c2ccc[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(-c2ccc[nH]2)cc1](/scaffold/IRTLROCMFSDSNF-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 673 to 720 of 882 chemicals
![4-Methyl-2-[3-(trifluoromethyl)phenyl]pyrrole chemical structure, C12H10F3N, CAS 1428932-15-3](/s/BVDXHVIJVRXZOS-UHFFFAOYSA-N.svg)
4-Methyl-2-[3-(trifluoromethyl)phenyl]pyrrole
CAS 1428932-15-3C12H10F3N
2-(2,4-Difluorophenyl)-4-methyl-1H-pyrrole
CAS 1351486-83-3C11H9F2N
5-(3-Aminophenyl)-1H-pyrrole-2-carbaldehyde
CAS 2138556-15-5C11H10N2O
4-Bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile
CAS 890929-78-9C15H10BrCl2F3N2O
4-Methyl-2-(o-tolyl)pyrrole
CAS 1428932-16-4C12H13N
Diethyl 5-(2-fluorophenyl)-3-hydroxy-1-methyl-1H-pyrrole-2,4-dicarboxylate
CAS 1263215-30-0C17H18FNO5
Diethyl 5-(3-fluorophenyl)-3-hydroxy-1-methyl-1H-pyrrole-2,4-dicarboxylate
CAS 1263215-38-8C17H18FNO5
Diethyl 5-(4-fluorophenyl)-3-hydroxy-1-methyl-1H-pyrrole-2,4-dicarboxylate
CAS 1263212-40-3C17H18FNO5
5-(3-Chloro-phenyl)-3-hydroxy-1-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester
CAS 1263216-40-5C17H18ClNO5
Methyl 5-(2-methoxy-5-methylphenyl)-1H-pyrrole-2-carboxylate
CAS 1361003-70-4C14H15NO3
Methyl 5-(5-ethyl-2-methoxyphenyl)-1H-pyrrole-2-carboxylate
CAS 1361004-18-3C15H17NO3
Methyl 5-(5-fluoro-2-methoxyphenyl)-1H-pyrrole-2-carboxylate
CAS 1361004-24-1C13H12FNO3
Methyl 5-(5-chloro-2-methoxyphenyl)-1H-pyrrole-2-carboxylate
CAS 1361003-99-7C13H12ClNO3
Methyl 5-(3-methoxyphenyl)-1H-pyrrole-2-carboxylate
CAS 1361004-05-8C13H13NO3
3-Methyl-4-(1H-pyrrol-2-yl)phenol
CAS 1694516-72-7C11H11NO
4-Methyl-2-(1H-pyrrol-2-yl)aniline
CAS 1567000-21-8C11H12N2
![5-[3-(Trifluoromethyl)phenyl]-1H-pyrrole-2-carboxylic acid chemical structure, C12H8F3NO2, CAS 41819-48-1](/s/VTRYQLKAHRPSAE-UHFFFAOYSA-N.svg)
5-[3-(Trifluoromethyl)phenyl]-1H-pyrrole-2-carboxylic acid
CAS 41819-48-1C12H8F3NO2
5-(2-Hydroxyphenyl)-1H-pyrrole-2-carboxylic acid
CAS 1894101-85-9C11H9NO3
Methyl 1-methyl-5-(3-(trifluoromethyl)phenyl)-1H-pyrrole-2-carboxylate
CAS 1893683-26-5C14H12F3NO2
5-(3-Aminophenyl)-1H-pyrrole-2-carboxylic acid
CAS 1894819-38-5C11H10N2O2
5-(3-Hydroxyphenyl)-1H-pyrrole-2-carboxylic acid
CAS 1894239-37-2C11H9NO3
5-(4-(Trifluoromethyl)phenyl)-1H-pyrrole-2-carboxylic acid
CAS 1894030-28-4C12H8F3NO2
![Methyl 1-Methyl-5-[4-(trifluoromethyl)phenyl]pyrrole-2-carboxylate chemical structure, C14H12F3NO2, CAS 1895780-61-6](/s/QDURUMAQIRPCON-UHFFFAOYSA-N.svg)
Methyl 1-Methyl-5-[4-(trifluoromethyl)phenyl]pyrrole-2-carboxylate
CAS 1895780-61-6C14H12F3NO2
5-(4-Aminophenyl)-1H-pyrrole-2-carboxylic acid
CAS 1891316-80-5C11H10N2O2
- Ethyl 5-(5-chloro-2-formylphenyl)-1,2-dimethyl-1H-pyrrole-3-carboxylate1644544-15-9C16H16ClNO3
- 4-Chloro-2-(4-(ethoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl)benzoic acid1644543-61-2C16H16ClNO4
- 2-[4-(Ethoxycarbonyl)-1-methyl-1H-pyrrol-2-yl]benzoic acid1648881-25-7C15H15NO4
- 3-Ethyl 5-(2-carboxy-4-chlorophenyl)-1,2-dimethyl-1H-pyrrole-3-carboxylate1648881-52-0C16H16ClNO4
- 3-Methyl 5-(2-carboxy-4-methoxyphenyl)-1,2-dimethyl-1H-pyrrole-3-carboxylate1648881-55-3C16H17NO5
- 3-Ethyl 5-(2-carboxy-5-chlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate1648881-26-8C15H14ClNO4
- 3-Ethyl 5-(2-carboxy-5-chlorophenyl)-1-ethyl-1H-pyrrole-3-carboxylate1648881-28-0C16H16ClNO4
- Ethyl 1-(2-hydroxyethyl)-4-methyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxylate1631030-77-7C17H18F3NO3
- Ethyl 4-methyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxylate1631030-76-6C15H14F3NO2
- Ethyl 2-chloro-4-methyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxylate1631030-75-5C15H13ClF3NO2
- 2-{2-Methyl-5-[4-(methylsulfanyl)phenyl]-1H-pyrrol-1-yl}ethan-1-ol494850-27-0C14H17NOS
- tert-Butyl 2-(5-chloro-2-methylphenyl)-4-iodo-1H-pyrrole-1-carboxylate1553981-82-0C16H17ClINO2
- tert-Butyl 2-(4-formylphenyl)-1H-pyrrole-1-carboxylate1008788-49-5C16H17NO3
- 5-(4-Methylphenyl)-1H-pyrrole-3-carboxylic acid250213-75-3C12H11NO2
- tert-Butyl methyl(5-phenyl-1H-pyrrol-3-yl)carbamate1956324-38-1C16H20N2O2
- 5-(4-Methoxyphenyl)-1H-pyrrole-3-carboxylic acid1956354-64-5C12H11NO3
- 3-(3-Oxalo-5-phenyl-1H-pyrrol-2-yl)propanoic acid1195981-64-6C15H13NO5
- 1-(4-Hydroxy-2-phenylpyrrol-1-yl)ethanone856097-96-6C12H11NO2
- 5-(4-Fluorophenyl)-1H-pyrrole-3-carboxylic acid250213-76-4C11H8FNO2
- 5-(4-Chloro-3,5-difluorophenyl)-1H-pyrrole-2-carboxylic acid2088211-40-7C11H6ClF2NO2
- 5-(4-Chlorophenyl)-4-methoxy-1H-pyrrole-2-carboxylic acid2088211-50-9C12H10ClNO3
- 5-(4-Chlorophenyl)-3-methoxy-1H-pyrrole-2-carbaldehyde2109229-18-5C12H10ClNO2
- 2-(3,4-Dimethoxyphenyl)-1H-pyrrole2096453-82-4C12H13NO2
- 5-(2-Fluorophenyl)-1H-pyrrole-2-carboxylic acid2092234-66-5C11H8FNO2
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c1ccc(-c2cscn2)cc1400 chemicals![Scaffold c1ccc(-c2cc[nH]n2)cc1](/scaffold/OEDUIFSDODUDRK-UHFFFAOYSA-N/structure.svg)
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