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Murcko scaffold

Ring system with 3 rings and 13 atoms

74 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
74
With full pages
19
Scaffold SMILES

c1ccc2c(c1)oc1cncnc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)oc1cncnc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 74 chemicals

Methyl [(2-methyl[1]benzofuro[3,2-d]pyrimidin-4-yl)sulfanyl]acetate chemical structure, C14H12N2O3S, CAS 294874-54-7
Methyl [(2-methyl[1]benzofuro[3,2-d]pyrimidin-4-yl)sulfanyl]acetate
CAS 294874-54-7C14H12N2O3S
Ethyl ([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)acetate chemical structure, C14H12N2O3S, CAS 294875-06-2
Ethyl ([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)acetate
CAS 294875-06-2C14H12N2O3S
4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine chemical structure, C11H7ClN2O, CAS 39786-40-8
4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine
CAS 39786-40-8C11H7ClN2O
6-Chloro-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,5,10,12-hexaene chemical structure, C10H5ClN2O, CAS 39876-88-5
6-Chloro-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,5,10,12-hexaene
CAS 39876-88-5C10H5ClN2O
4,8-Dichlorobenzofuro[3,2-d]pyrimidine chemical structure, C10H4Cl2N2O, CAS 294874-71-8
4,8-Dichlorobenzofuro[3,2-d]pyrimidine
CAS 294874-71-8C10H4Cl2N2O
2-((2-Methylbenzofuro[3,2-d]pyrimidin-4-yl)thio)ethanol chemical structure, C13H12N2O2S, CAS 845666-47-9
2-((2-Methylbenzofuro[3,2-d]pyrimidin-4-yl)thio)ethanol
CAS 845666-47-9C13H12N2O2S
4-(Ethylthio)benzofuro[3,2-d]pyrimidine chemical structure, C12H10N2OS, CAS 62208-73-5
4-(Ethylthio)benzofuro[3,2-d]pyrimidine
CAS 62208-73-5C12H10N2OS
4-Ethylsulfanyl-2-methyl-[1]benzofuro[3,2-d]pyrimidine chemical structure, C13H12N2OS, CAS 68217-85-6
4-Ethylsulfanyl-2-methyl-[1]benzofuro[3,2-d]pyrimidine
CAS 68217-85-6C13H12N2OS
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)ethanol chemical structure, C12H10N2O2S, CAS 848754-20-1
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)ethanol
CAS 848754-20-1C12H10N2O2S
2-[(2-Ethyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)sulfanyl]ethanol chemical structure, C14H14N2O2S, CAS 850827-73-5
2-[(2-Ethyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)sulfanyl]ethanol
CAS 850827-73-5C14H14N2O2S
Benzofuro[3,2-d]pyrimidin-4-yl-D-alanine chemical structure, C13H11N3O3, CAS 1212274-58-2
Benzofuro[3,2-d]pyrimidin-4-yl-D-alanine
CAS 1212274-58-2C13H11N3O3
4-(Benzofuro[3,2-d]pyrimidin-4-ylamino)butanoic acid chemical structure, C14H13N3O3, CAS 330818-01-4
4-(Benzofuro[3,2-d]pyrimidin-4-ylamino)butanoic acid
CAS 330818-01-4C14H13N3O3
2-([1]Benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)acetonitrile chemical structure, C12H7N3OS, CAS 844861-03-6
2-([1]Benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)acetonitrile
CAS 844861-03-6C12H7N3OS
4-((2-Methylbenzofuro[3,2-d]pyrimidin-4-yl)amino)butanoic acid chemical structure, C15H15N3O3, CAS 845633-47-8
4-((2-Methylbenzofuro[3,2-d]pyrimidin-4-yl)amino)butanoic acid
CAS 845633-47-8C15H15N3O3
2-(Benzofuro[3,2-d]pyrimidin-4-yloxy)-N,N-dimethylethanamine chemical structure, C14H15N3O2, CAS 832147-71-4
2-(Benzofuro[3,2-d]pyrimidin-4-yloxy)-N,N-dimethylethanamine
CAS 832147-71-4C14H15N3O2
4-(Propylthio)benzofuro[3,2-d]pyrimidine chemical structure, C13H12N2OS, CAS 851130-43-3
4-(Propylthio)benzofuro[3,2-d]pyrimidine
CAS 851130-43-3C13H12N2OS
4-(Isopropylthio)benzofuro[3,2-d]pyrimidine chemical structure, C13H12N2OS, CAS 851130-44-4
4-(Isopropylthio)benzofuro[3,2-d]pyrimidine
CAS 851130-44-4C13H12N2OS
(Benzo[4,5]furo[3,2-d]pyrimidin-4-ylamino)-acetic acid chemical structure, C12H9N3O3, CAS 326009-17-0
(Benzo[4,5]furo[3,2-d]pyrimidin-4-ylamino)-acetic acid
CAS 326009-17-0C12H9N3O3
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)acetic acid chemical structure, C12H8N2O3S, CAS 304861-66-3
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)acetic acid
CAS 304861-66-3C12H8N2O3S
2-(Benzo[4,5]furo[3,2-d]pyrimidin-4-ylamino)-propionic acid chemical structure, C13H11N3O3, CAS 499104-82-4
2-(Benzo[4,5]furo[3,2-d]pyrimidin-4-ylamino)-propionic acid
CAS 499104-82-4C13H11N3O3
6-Hydrazinyl-8-oxa-3,5-diazatricyclo(7.4.0.0,2,7)trideca-1(9),2(7),3,5,10,12-hexaene chemical structure, C10H8N4O, CAS 65024-00-2
6-Hydrazinyl-8-oxa-3,5-diazatricyclo(7.4.0.0,2,7)trideca-1(9),2(7),3,5,10,12-hexaene
CAS 65024-00-2C10H8N4O
4-Methoxybenzofuro[3,2-d]pyrimidine chemical structure, C11H8N2O2, CAS 62208-69-9
4-Methoxybenzofuro[3,2-d]pyrimidine
CAS 62208-69-9C11H8N2O2
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)acetamide chemical structure, C12H9N3O2S, CAS 847337-32-0
2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)acetamide
CAS 847337-32-0C12H9N3O2S
2-Ethyl-4-(methylsulfanyl)[1]benzofuro[3,2-d]pyrimidine chemical structure, C13H12N2OS, CAS 877647-78-4
2-Ethyl-4-(methylsulfanyl)[1]benzofuro[3,2-d]pyrimidine
CAS 877647-78-4C13H12N2OS