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Murcko scaffold

Ring system with 4 rings and 20 atoms

63 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 20
Chemicals: 63
With full pages: 8

Scaffold SMILES

c1ccc2c(c1)N=C(N1CCNCC1)c1ccsc1N2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc2c(c1)N=C(N1CCNCC1)c1ccsc1N2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 63 chemicals

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-8-methyl-4-(4-methyl-1-piperazinyl)- chemical structure, C19H24N4S, CAS 61325-77-7

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-8-methyl-4-(4-methyl-1-piperazinyl)-

CAS 61325-77-7C₁₉H₂₄N₄S

10H-Thieno(2,3-b)(1,5)benzodiazepine, 6,8-difluoro-2-ethyl-4-(4-methyl-1-piperazinyl)-, maleate chemical structure, C22H24F2N4O4S, CAS 61325-74-4

10H-Thieno(2,3-b)(1,5)benzodiazepine, 6,8-difluoro-2-ethyl-4-(4-methyl-1-piperazinyl)-, maleate

CAS 61325-74-4C₂₂H₂₄F₂N₄O₄S

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-8-fluoro-4-(4-methyl-1-piperazinyl)-, maleate chemical structure, C22H25FN4O4S, CAS 61431-30-9

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-8-fluoro-4-(4-methyl-1-piperazinyl)-, maleate

CAS 61431-30-9C₂₂H₂₅FN₄O₄S

2,10-Dimethyl-4-(4-methyl-1-piperazinyl)-10H-thieno-[2,3-b][1,5]benzodiazepine chemical structure, C18H22N4S, CAS 155817-84-8

2,10-Dimethyl-4-(4-methyl-1-piperazinyl)-10H-thieno-[2,3-b][1,5]benzodiazepine

CAS 155817-84-8C₁₈H₂₂N₄S

(S)-6-Fluoro-10-[3-(2-methoxy-ethyl)-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene chemical structure, C19H23FN4OS, CAS 660864-26-6

(S)-6-Fluoro-10-[3-(2-methoxy-ethyl)-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene

CAS 660864-26-6C₁₉H₂₃FN₄OS

8-Fluoro-4-[3-(2-methoxyethyl)piperazin-1-yl]-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine chemical structure, C19H23FN4OS

8-Fluoro-4-[3-(2-methoxyethyl)piperazin-1-yl]-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine

C₁₉H₂₃FN₄OS

Olanzapine chemical structure, C17H20N4S, CAS 132539-06-1

CAS 132539-06-1C₁₇H₂₀N₄S

2-Ethyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine chemical structure, C18H22N4S, CAS 61325-71-1

2-Ethyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine

CAS 61325-71-1C₁₈H₂₂N₄S

Olanzapine-N-oxide chemical structure, C17H20N4OS, CAS 174794-02-6

Olanzapine-N-oxide

CAS 174794-02-6C₁₇H₂₀N₄OS

Flumezapine chemical structure, C17H19FN4S, CAS 61325-80-2

CAS 61325-80-2C₁₇H₁₉FN₄S

Desmethylolanzapine chemical structure, C16H18N4S, CAS 161696-76-0

Desmethylolanzapine

CAS 161696-76-0C₁₆H₁₈N₄S

Olanzapine LIP 1 Acetyl chemical structure, C18H20N4OS, CAS 935272-10-9

Olanzapine LIP 1 Acetyl

CAS 935272-10-9C₁₈H₂₀N₄OS

Chloromethyl olanzapinium chemical structure, C18H22ClN4S+, CAS 735264-27-4

Chloromethyl olanzapinium

CAS 735264-27-4C₁₈H₂₂ClN₄S+

N-Demethyl-N-formylolanzapine chemical structure, C17H18N4OS, CAS 639460-79-0

N-Demethyl-N-formylolanzapine

CAS 639460-79-0C₁₇H₁₈N₄OS

4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol chemical structure, C17H20N4OS, CAS 174756-45-7

4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol

CAS 174756-45-7C₁₇H₂₀N₄OS

Olanzapine benzoate chemical structure, C24H26N4O2S, CAS 861390-70-7

Olanzapine benzoate

CAS 861390-70-7C₂₄H₂₆N₄O₂S

N-Chloromethyl olanzapine chloride chemical structure, C18H22Cl2N4S, CAS 719300-59-1

N-Chloromethyl olanzapine chloride

CAS 719300-59-1C₁₈H₂₂Cl₂N₄S

Olanzapine tartrate chemical structure, C21H26N4O6S, CAS 491828-16-1

Olanzapine tartrate

CAS 491828-16-1C₂₁H₂₆N₄O₆S

Olanzapine hydrochloride chemical structure, C17H21ClN4S, CAS 783334-36-1

Olanzapine hydrochloride

CAS 783334-36-1C₁₇H₂₁ClN₄S

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-7-fluoro-4-(4-methyl-1-piperazinyl)- chemical structure, C18H21FN4S, CAS 61325-70-0

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-ethyl-7-fluoro-4-(4-methyl-1-piperazinyl)-

CAS 61325-70-0C₁₈H₂₁FN₄S

Symbyax chemical structure, C34H39ClF3N5OS, CAS 250603-12-4

CAS 250603-12-4C₃₄H₃₉ClF₃N₅OS

10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(1-piperazinyl)- chemical structure, C16H17FN4S, CAS 74162-33-7

10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(1-piperazinyl)-

CAS 74162-33-7C₁₆H₁₇FN₄S

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-tert-butyl-4-(4-methyl-1-piperazinyl)- chemical structure, C20H26N4S, CAS 74162-35-9

10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-tert-butyl-4-(4-methyl-1-piperazinyl)-

CAS 74162-35-9C₂₀H₂₆N₄S

10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-, 4'-N-oxide chemical structure, C17H19FN4OS, CAS 74162-36-0

10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-, 4'-N-oxide

CAS 74162-36-0C₁₇H₁₉FN₄OS