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Murcko scaffold

Ring system with 3 rings and 24 atoms

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
39
With full pages
4
Scaffold SMILES

O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

4-[3-(4-Phenylmethoxyphenyl)prop-2-enoyl]benzonitrile chemical structure, C23H17NO2, CAS 33084-01-4
4-[3-(4-Phenylmethoxyphenyl)prop-2-enoyl]benzonitrile
CAS 33084-01-4C23H17NO2
2-Benzoyl-3-{3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxyphenyl}prop-2-enenitrile chemical structure, C24H17BrClNO3, CAS 5498-89-5
2-Benzoyl-3-{3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxyphenyl}prop-2-enenitrile
CAS 5498-89-5C24H17BrClNO3
2-Benzoyl-3-[3-bromo-4-[(4-fluorophenyl)methoxy]phenyl]prop-2-enenitrile chemical structure, C23H15BrFNO2, CAS 5509-80-8
2-Benzoyl-3-[3-bromo-4-[(4-fluorophenyl)methoxy]phenyl]prop-2-enenitrile
CAS 5509-80-8C23H15BrFNO2
4-Benzyloxy-4'-methylchalcone chemical structure, C23H20O2, CAS 86711-45-7
4-Benzyloxy-4'-methylchalcone
CAS 86711-45-7C23H20O2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-bromophenyl)prop-2-en-1-one chemical structure, C22H17BrO2, CAS 358656-11-8
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-bromophenyl)prop-2-en-1-one
CAS 358656-11-8C22H17BrO2
4-Benzyloxy-4'-chlorochalcone chemical structure, C22H17ClO2, CAS 86711-44-6
4-Benzyloxy-4'-chlorochalcone
CAS 86711-44-6C22H17ClO2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one chemical structure, C24H22O3, CAS 358343-63-2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one
CAS 358343-63-2C24H22O3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)prop-2-en-1-one chemical structure, C22H17FO2, CAS 1152162-39-4
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)prop-2-en-1-one
CAS 1152162-39-4C22H17FO2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-bromophenyl)prop-2-en-1-one chemical structure, C22H17BrO2, CAS 358655-92-2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-bromophenyl)prop-2-en-1-one
CAS 358655-92-2C22H17BrO2
3-[4-(Benzyloxy)phenyl]-1-(2,4-dimethoxyphenyl)prop-2-en-1-one chemical structure, C24H22O4, CAS 256457-60-0
3-[4-(Benzyloxy)phenyl]-1-(2,4-dimethoxyphenyl)prop-2-en-1-one
CAS 256457-60-0C24H22O4
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-methoxyphenyl)prop-2-en-1-one chemical structure, C23H20O3, CAS 358656-54-9
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-methoxyphenyl)prop-2-en-1-one
CAS 358656-54-9C23H20O3
(E)-3-[4-[(2-Chlorophenyl)methoxy]-3-ethoxyphenyl]-1-phenylprop-2-en-1-one chemical structure, C24H21ClO3, CAS 404916-13-8
(E)-3-[4-[(2-Chlorophenyl)methoxy]-3-ethoxyphenyl]-1-phenylprop-2-en-1-one
CAS 404916-13-8C24H21ClO3
(E)-3-[4-[(2-Chlorophenyl)methoxy]-3-ethoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one chemical structure, C24H21ClO4, CAS 378217-25-5
(E)-3-[4-[(2-Chlorophenyl)methoxy]-3-ethoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
CAS 378217-25-5C24H21ClO4
4-[(E)-3-(4-Phenylmethoxyphenyl)prop-2-enoyl]benzonitrile chemical structure, C23H17NO2
4-[(E)-3-(4-Phenylmethoxyphenyl)prop-2-enoyl]benzonitrile
C23H17NO2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C23H20O3, CAS 1152162-36-1
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one
CAS 1152162-36-1C23H20O3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2-chlorophenyl)prop-2-en-1-one chemical structure, C22H17ClO2, CAS 909774-57-8
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2-chlorophenyl)prop-2-en-1-one
CAS 909774-57-8C22H17ClO2
4-Benzyloxy-2',3,4',6'-tetramethoxychalcone chemical structure, C26H26O6, CAS 1017900-43-4
4-Benzyloxy-2',3,4',6'-tetramethoxychalcone
CAS 1017900-43-4C26H26O6
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one chemical structure, C23H20O3, CAS 906635-45-8
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one
CAS 906635-45-8C23H20O3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-nitrophenyl)prop-2-en-1-one chemical structure, C22H17NO4, CAS 358657-05-3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-nitrophenyl)prop-2-en-1-one
CAS 358657-05-3C22H17NO4
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-nitrophenyl)prop-2-en-1-one chemical structure, C22H17NO4, CAS 909771-47-7
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-nitrophenyl)prop-2-en-1-one
CAS 909771-47-7C22H17NO4
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one chemical structure, C22H18O3, CAS 1447848-18-1
(2E)-3-[4-(Benzyloxy)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
CAS 1447848-18-1C22H18O3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2,4-dichlorophenyl)prop-2-en-1-one chemical structure, C22H16Cl2O2, CAS 807338-48-3
(2E)-3-[4-(Benzyloxy)phenyl]-1-(2,4-dichlorophenyl)prop-2-en-1-one
CAS 807338-48-3C22H16Cl2O2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-methylphenyl)prop-2-en-1-one chemical structure, C23H20O2, CAS 907167-00-4
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-methylphenyl)prop-2-en-1-one
CAS 907167-00-4C23H20O2
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-chlorophenyl)prop-2-en-1-one chemical structure, C22H17ClO2, CAS 906726-00-9
(2E)-3-[4-(Benzyloxy)phenyl]-1-(3-chlorophenyl)prop-2-en-1-one
CAS 906726-00-9C22H17ClO2