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Murcko scaffold

Ring system with 3 rings and 25 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
19
With full pages
5
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc(NC(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc(NC(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-Fluoro-N-(4-{[(4-methoxyphenyl)acetyl]amino}phenyl)benzamide chemical structure, C22H19FN2O3, CAS 708280-05-1
2-Fluoro-N-(4-{[(4-methoxyphenyl)acetyl]amino}phenyl)benzamide
CAS 708280-05-1C22H19FN2O3
3,5-Dichloro-2-methoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide chemical structure, C22H18Cl2N2O3, CAS 767316-30-3
3,5-Dichloro-2-methoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide
CAS 767316-30-3C22H18Cl2N2O3
2,3,5,6-Tetrafluoro-4-methoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C22H16F4N2O3, CAS 838843-50-8
2,3,5,6-Tetrafluoro-4-methoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 838843-50-8C22H16F4N2O3
5-Bromo-2-methoxy-3-methyl-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide chemical structure, C23H21BrN2O3, CAS 709005-20-9
5-Bromo-2-methoxy-3-methyl-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide
CAS 709005-20-9C23H21BrN2O3
N-[2,5-Dimethoxy-4-[[2-(4-methylphenyl)acetyl]amino]phenyl]benzamide chemical structure, C24H24N2O4, CAS 587843-95-6
N-[2,5-Dimethoxy-4-[[2-(4-methylphenyl)acetyl]amino]phenyl]benzamide
CAS 587843-95-6C24H24N2O4
N-[4-[[2-(4-Fluorophenyl)acetyl]amino]-2,5-dimethoxyphenyl]benzamide chemical structure, C23H21FN2O4, CAS 667408-74-4
N-[4-[[2-(4-Fluorophenyl)acetyl]amino]-2,5-dimethoxyphenyl]benzamide
CAS 667408-74-4C23H21FN2O4
2-Chloro-N-(4-{[(4-chlorophenyl)acetyl]amino}-2-methoxyphenyl)benzamide chemical structure, C22H18Cl2N2O3, CAS 673499-65-5
2-Chloro-N-(4-{[(4-chlorophenyl)acetyl]amino}-2-methoxyphenyl)benzamide
CAS 673499-65-5C22H18Cl2N2O3
N-(4-{[(4-Chlorophenyl)acetyl]amino}phenyl)-3-methylbenzamide chemical structure, C22H19ClN2O2, CAS 674366-80-4
N-(4-{[(4-Chlorophenyl)acetyl]amino}phenyl)-3-methylbenzamide
CAS 674366-80-4C22H19ClN2O2
2,4-Dichloro-N-[4-[[2-(4-chlorophenyl)acetyl]amino]phenyl]benzamide chemical structure, C21H15Cl3N2O2, CAS 425647-97-8
2,4-Dichloro-N-[4-[[2-(4-chlorophenyl)acetyl]amino]phenyl]benzamide
CAS 425647-97-8C21H15Cl3N2O2
4-tert-Butyl-N-(4-{[(3,4-dimethoxyphenyl)acetyl]amino}phenyl)benzamide chemical structure, C27H30N2O4, CAS 354768-22-2
4-tert-Butyl-N-(4-{[(3,4-dimethoxyphenyl)acetyl]amino}phenyl)benzamide
CAS 354768-22-2C27H30N2O4
2,3,4,5,6-Pentafluoro-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C21H13F5N2O2, CAS 700854-49-5
2,3,4,5,6-Pentafluoro-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 700854-49-5C21H13F5N2O2
3-Bromo-4-methoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C22H19BrN2O3, CAS 833444-85-2
3-Bromo-4-methoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 833444-85-2C22H19BrN2O3
3,4,5-Triethoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide chemical structure, C27H30N2O5, CAS 765926-71-4
3,4,5-Triethoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide
CAS 765926-71-4C27H30N2O5
3-Chloro-4-ethoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C23H21ClN2O3, CAS 833435-65-7
3-Chloro-4-ethoxy-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 833435-65-7C23H21ClN2O3
3,4-Dimethyl-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C23H22N2O2, CAS 842117-03-7
3,4-Dimethyl-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 842117-03-7C23H22N2O2
3,5-Dichloro-4-methoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide chemical structure, C22H18Cl2N2O3, CAS 896661-81-7
3,5-Dichloro-4-methoxy-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide
CAS 896661-81-7C22H18Cl2N2O3
4-Ethoxy-3-nitro-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide chemical structure, C23H21N3O5, CAS 835886-67-4
4-Ethoxy-3-nitro-N-[4-[(2-phenylacetyl)amino]phenyl]benzamide
CAS 835886-67-4C23H21N3O5
3-Methyl-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C22H20N2O2, CAS 420829-13-6
3-Methyl-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 420829-13-6C22H20N2O2
2-Fluoro-N-{4-[(phenylacetyl)amino]phenyl}benzamide chemical structure, C21H17FN2O2, CAS 900751-92-0
2-Fluoro-N-{4-[(phenylacetyl)amino]phenyl}benzamide
CAS 900751-92-0C21H17FN2O2