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Murcko scaffold

Ring system with 3 rings and 24 atoms

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
31
With full pages
8
Scaffold SMILES

S=C(Nc1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

N-Phenyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide chemical structure, C20H23N3S, CAS 332053-02-8
N-Phenyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide
CAS 332053-02-8C20H23N3S
N-(4-Methylphenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide chemical structure, C21H25N3S, CAS 431912-08-2
N-(4-Methylphenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide
CAS 431912-08-2C21H25N3S
N-(2,4-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C22H27N3S, CAS 482595-06-2
N-(2,4-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 482595-06-2C22H27N3S
N-(3-Chloro-2-methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H24ClN3S, CAS 474250-21-0
N-(3-Chloro-2-methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 474250-21-0C21H24ClN3S
N-(4-Chloro-2-methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H24ClN3S, CAS 664969-05-5
N-(4-Chloro-2-methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 664969-05-5C21H24ClN3S
4-Cinnamyl-N-(4-fluorophenyl)-1-piperazinecarbothioamide chemical structure, C20H22FN3S, CAS 330865-89-9
4-Cinnamyl-N-(4-fluorophenyl)-1-piperazinecarbothioamide
CAS 330865-89-9C20H22FN3S
N-(3,5-Dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C22H27N3O2S, CAS 1164530-13-5
N-(3,5-Dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 1164530-13-5C22H27N3O2S
4-[(2E)-3-Phenylprop-2-en-1-yl]-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide chemical structure, C20H24N4O2S2, CAS 664969-54-4
4-[(2E)-3-Phenylprop-2-en-1-yl]-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide
CAS 664969-54-4C20H24N4O2S2
N-(2-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H25N3OS, CAS 1164494-61-4
N-(2-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 1164494-61-4C21H25N3OS
N-(3-Chloro-4-fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H21ClFN3S, CAS 709003-51-0
N-(3-Chloro-4-fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 709003-51-0C20H21ClFN3S
N-(3-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H25N3OS, CAS 1164469-01-5
N-(3-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 1164469-01-5C21H25N3OS
N-(2-Chlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H22ClN3S, CAS 690692-65-0
N-(2-Chlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 690692-65-0C20H22ClN3S
N-(4-Bromophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H22BrN3S, CAS 690696-41-4
N-(4-Bromophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 690696-41-4C20H22BrN3S
N-(3-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H22FN3S, CAS 690706-94-6
N-(3-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 690706-94-6C20H22FN3S
N-(2-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H25N3S, CAS 690696-95-8
N-(2-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 690696-95-8C21H25N3S
N-(2,4-Dichlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H21Cl2N3S, CAS 431073-06-2
N-(2,4-Dichlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 431073-06-2C20H21Cl2N3S
N-(4-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H25N3OS, CAS 1164545-63-4
N-(4-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 1164545-63-4C21H25N3OS
N-(2-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H22FN3S, CAS 1164554-43-1
N-(2-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 1164554-43-1C20H22FN3S
N-(4-Chlorophenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide chemical structure, C20H22ClN3S, CAS 431891-08-6
N-(4-Chlorophenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carbothioamide
CAS 431891-08-6C20H22ClN3S
N-(3-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C21H25N3S, CAS 431891-54-2
N-(3-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 431891-54-2C21H25N3S
N-(3,4-Dichlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H21Cl2N3S, CAS 431922-61-1
N-(3,4-Dichlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 431922-61-1C20H21Cl2N3S
N-(3-Chlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C20H22ClN3S, CAS 430471-17-3
N-(3-Chlorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 430471-17-3C20H22ClN3S
N-(2,4-Dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C22H27N3O2S, CAS 693242-01-2
N-(2,4-Dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 693242-01-2C22H27N3O2S
N-(4-Chloro-2,5-dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C22H26ClN3O2S, CAS 675141-54-5
N-(4-Chloro-2,5-dimethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 675141-54-5C22H26ClN3O2S