Murcko scaffold
Ring system with 2 rings and 15 atoms
105 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 105
- With full pages
- 21
Scaffold SMILES
O=C(Nc1ccccc1)C1CC=CCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 105 chemicals
![6-[(3-Hydroxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C14H15NO4, CAS 220991-93-5](/s/ZWYQUQOTFJTIRZ-UHFFFAOYSA-N.svg)
6-[(3-Hydroxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 220991-93-5C14H15NO4
6-(Phenylcarbamoyl)cyclohex-3-ene-1-carboxylic acid
CAS 59157-31-2C14H15NO3
![6-[(2-Methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H17NO3, CAS 296246-13-4](/s/OPLGDXIYOJUPRU-UHFFFAOYSA-N.svg)
6-[(2-Methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 296246-13-4C15H17NO3
![6-[(3-Chloro-4-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H16ClNO3, CAS 19989-14-1](/s/YPFYXQWSXYLTBQ-UHFFFAOYSA-N.svg)
6-[(3-Chloro-4-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 19989-14-1C15H16ClNO3
RefChem:381328
CAS 5768-69-4C18H21NO5
![6-[(2-Methoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H17NO4, CAS 326920-49-4](/s/DCJSHKQYJZNXTJ-UHFFFAOYSA-N.svg)
6-[(2-Methoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 326920-49-4C15H17NO4
![2,3,3-Trichloroprop-2-en-1-yl 6-[(4-iodophenyl)carbamoyl]cyclohex-3-ene-1-carboxylate chemical structure, C17H15Cl3INO3, CAS 5190-21-6](/s/BPVGSFDYMWRPDP-UHFFFAOYSA-N.svg)
2,3,3-Trichloroprop-2-en-1-yl 6-[(4-iodophenyl)carbamoyl]cyclohex-3-ene-1-carboxylate
CAS 5190-21-6C17H15Cl3INO3
![6-[(2,4-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C16H19NO3, CAS 198283-89-5](/s/UXTUZDVBTDNMIU-UHFFFAOYSA-N.svg)
6-[(2,4-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 198283-89-5C16H19NO3
![6-[(4-Butoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C18H23NO4, CAS 5617-62-9](/s/NJAPPTUEIXBLNI-UHFFFAOYSA-N.svg)
6-[(4-Butoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 5617-62-9C18H23NO4
![6-[(3-Methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H17NO3, CAS 330833-35-7](/s/OCEVOKQSAMKYJY-UHFFFAOYSA-N.svg)
6-[(3-Methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 330833-35-7C15H17NO3
![4-{[(6-Carboxycyclohex-3-en-1-yl)carbonyl]amino}-2-hydroxybenzoic acid chemical structure, C15H15NO6, CAS 303138-49-0](/s/ARAOHCKDOBBGLE-UHFFFAOYSA-N.svg)
4-{[(6-Carboxycyclohex-3-en-1-yl)carbonyl]amino}-2-hydroxybenzoic acid
CAS 303138-49-0C15H15NO6
![6-[(4-Iodophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C14H14INO3, CAS 200060-20-4](/s/CNBCFMDYNFYBIT-UHFFFAOYSA-N.svg)
6-[(4-Iodophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 200060-20-4C14H14INO3
![6-{[4-(Methoxycarbonyl)anilino]carbonyl}-3-cyclohexene-1-carboxylic acid chemical structure, C16H17NO5, CAS 352644-32-7](/s/GIYQEAMTVKFESX-UHFFFAOYSA-N.svg)
6-{[4-(Methoxycarbonyl)anilino]carbonyl}-3-cyclohexene-1-carboxylic acid
CAS 352644-32-7C16H17NO5
![6-[(2,5-Dimethoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C16H19NO5, CAS 499986-36-6](/s/OMMCLSTYKQPZHQ-UHFFFAOYSA-N.svg)
6-[(2,5-Dimethoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 499986-36-6C16H19NO5
![6-[(3-Fluorophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C14H14FNO3, CAS 364617-05-0](/s/NYBMUEVAQMGPNW-UHFFFAOYSA-N.svg)
6-[(3-Fluorophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 364617-05-0C14H14FNO3
3'-(Trifluoromethyl)-1,2,3,6-tetrahydrophthalanilic acid
CAS 19849-08-2C15H14F3NO3
![6-[(2,5-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C16H19NO3, CAS 328009-45-6](/s/JKNZNZPXDDOWOY-UHFFFAOYSA-N.svg)
6-[(2,5-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 328009-45-6C16H19NO3
![6-[(2-Bromo-4-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H16BrNO3, CAS 353475-96-4](/s/PQICXQMAYOCLRN-UHFFFAOYSA-N.svg)
6-[(2-Bromo-4-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 353475-96-4C15H16BrNO3
![6-[(3,4-Difluoroanilino)-oxomethyl]-1-cyclohex-3-enecarboxylic acid chemical structure, C14H13F2NO3, CAS 353475-90-8](/s/VIOGDFJFJUBWAY-UHFFFAOYSA-N.svg)
6-[(3,4-Difluoroanilino)-oxomethyl]-1-cyclohex-3-enecarboxylic acid
CAS 353475-90-8C14H13F2NO3
![6-[(3-Ethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C16H19NO3, CAS 352690-85-8](/s/LOJRHZKWIGIKBC-UHFFFAOYSA-N.svg)
6-[(3-Ethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 352690-85-8C16H19NO3
![6-[(4-Bromoanilino)carbonyl]-3,4-dimethyl-3-cyclohexene-1-carboxylic acid chemical structure, C16H18BrNO3, CAS 401629-61-6](/s/XAZMYHWJZOAHHV-UHFFFAOYSA-N.svg)
6-[(4-Bromoanilino)carbonyl]-3,4-dimethyl-3-cyclohexene-1-carboxylic acid
CAS 401629-61-6C16H18BrNO3
![6-[(2-Carbamoylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C15H16N2O4, CAS 353473-47-9](/s/SQKJRTVGTVKOTB-UHFFFAOYSA-N.svg)
6-[(2-Carbamoylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 353473-47-9C15H16N2O4
![6-[[4-(Carboxymethyl)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid chemical structure, C16H17NO5, CAS 351157-71-6](/s/FFYSVGSKVNSEGP-UHFFFAOYSA-N.svg)
6-[[4-(Carboxymethyl)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid
CAS 351157-71-6C16H17NO5
![3-{[(6-Carboxycyclohex-3-en-1-yl)carbonyl]amino}-4-methylbenzoic acid chemical structure, C16H17NO5, CAS 351465-64-0](/s/GKIJHFZQSITLDG-UHFFFAOYSA-N.svg)
3-{[(6-Carboxycyclohex-3-en-1-yl)carbonyl]amino}-4-methylbenzoic acid
CAS 351465-64-0C16H17NO5
- 6-(4-Fluoro-phenylcarbamoyl)-3,4-dimethyl-cyclohex-3-enecarboxylic acid401629-70-7C16H18FNO3
- 6-[(4-Ethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid428505-35-5C16H19NO3
- 6-[(4-Chlorophenyl)carbamoyl]-3,4-dimethylcyclohex-3-ene-1-carboxylic acid96599-85-8C16H18ClNO3
- Isopropyl 6-{[(4-chlorophenyl)amino]carbonyl}-3-cyclohexene-1-carboxylate432496-29-2C17H20ClNO3
- Butan-2-yl 6-[(4-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylate474089-40-2C19H25NO3
- 6-[(5-tert-Butyl-2-methoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid312507-84-9C19H25NO4
- 6-[(4-Cyanophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid309970-76-1C15H14N2O3
- 6-[(5-Chloro-2-methylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid339022-00-3C15H16ClNO3
- 6-[(2-Ethoxyphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid346446-21-7C16H19NO4
- 6-[(2-Fluoroanilino)carbonyl]-3-cyclohexene-1-carboxylic acid346446-20-6C14H14FNO3
- 6-[(3-Nitrophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid200422-30-6C14H14N2O5
- 6-[(2,5-Dichlorophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid197799-94-3C14H13Cl2NO3
- 6-[(2,6-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid198283-90-8C16H19NO3
- 6-[(2-Methoxycarbonylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid353786-64-8C16H17NO5
- 6-[[2-(Trifluoromethyl)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid438454-51-4C15H14F3NO3
- 6-[(2-Chloro-5-nitrophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid541539-03-1C14H13ClN2O5
- 6-[(4-Butylphenyl)carbamoyl]-3,4-dimethylcyclohex-3-ene-1-carboxylic acid492437-76-0C20H27NO3
- 1,4-Benzenedicarboxylic acid, 2-[[(6-carboxy-3-cyclohexen-1-yl)carbonyl]amino]-, 1,4-dimethyl ester352701-13-4C18H19NO7
- 6-[(2-Bromo-4-methylphenyl)carbamoyl]-4-chlorocyclohex-3-ene-1-carboxylic acid664993-16-2C15H15BrClNO3
- 6-[(2-Methoxyanilino)carbonyl]-1-methyl-3-cyclohexene-1-carboxylic acid664993-15-1C16H19NO4
- 5-{[(6-Carboxycyclohex-3-en-1-yl)carbonyl]amino}-2-chlorobenzoic acid714209-46-8C15H14ClNO5
- 6-[(2,3-Dichlorophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid355383-57-2C14H13Cl2NO3
- 6-[(3-Chlorophenyl)carbamoyl]-3,4-dimethylcyclohex-3-ene-1-carboxylic acid96599-46-1C16H18ClNO3
- 6-[(3,5-Dimethylphenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid198283-91-9C16H19NO3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
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c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
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C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals