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Murcko scaffold

1H-Imidazole, 1,5-diphenyl- scaffold

509 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
509
With full pages
4
Scaffold SMILES

c1ccc(-c2cncn2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Imidazole, 1,5-diphenyl- page
Murcko scaffold c1ccc(-c2cncn2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 509 chemicals

Cimicoxib chemical structure, C16H13ClFN3O3S, CAS 265114-23-6
Cimicoxib
CAS 265114-23-6C16H13ClFN3O3S
1H-Imidazole, 1,5-diphenyl- chemical structure, C15H12N2, CAS 61278-58-8
1H-Imidazole, 1,5-diphenyl-
CAS 61278-58-8C15H12N2
2-{[5-(4-Chlorophenyl)-1-(2-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(1-cyano-1,2-dimethylpropyl)acetamide chemical structure, C24H25ClN4OS, CAS 786715-89-7
2-{[5-(4-Chlorophenyl)-1-(2-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(1-cyano-1,2-dimethylpropyl)acetamide
CAS 786715-89-7C24H25ClN4OS
4-Chloro-1-(4-methylsulfonylphenyl)-5-(4-propylphenyl)imidazole chemical structure, C19H19ClN2O2S, CAS 578726-74-6
4-Chloro-1-(4-methylsulfonylphenyl)-5-(4-propylphenyl)imidazole
CAS 578726-74-6C19H19ClN2O2S
4-(4-Chloro-5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl)-N-(1,1-dimethylethyl)benzenesulfonamide chemical structure, C20H21ClFN3O3S, CAS 499777-85-4
4-(4-Chloro-5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl)-N-(1,1-dimethylethyl)benzenesulfonamide
CAS 499777-85-4C20H21ClFN3O3S
1H-Imidazole, 1-(4-fluorophenyl)-5-[4-(methylthio)phenyl]- chemical structure, C16H13FN2S, CAS 265113-37-9
1H-Imidazole, 1-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-
CAS 265113-37-9C16H13FN2S
1H-Imidazole, 5-(4-fluorophenyl)-1-[4-(methylthio)phenyl]- chemical structure, C16H13FN2S, CAS 578727-01-2
1H-Imidazole, 5-(4-fluorophenyl)-1-[4-(methylthio)phenyl]-
CAS 578727-01-2C16H13FN2S
4-Ethyl-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole chemical structure, C18H17FN2O2S, CAS 578726-92-8
4-Ethyl-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole
CAS 578726-92-8C18H17FN2O2S
1-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1H-imidazole chemical structure, C16H13ClN2O, CAS 852525-36-1
1-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1H-imidazole
CAS 852525-36-1C16H13ClN2O
5-(3-Fluoro-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-imidazole chemical structure, C19H19FN2O4, CAS 852525-35-0
5-(3-Fluoro-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-imidazole
CAS 852525-35-0C19H19FN2O4
1,5-Bis(4-methoxyphenyl)-1H-imidazole chemical structure, C17H16N2O2, CAS 852525-32-7
1,5-Bis(4-methoxyphenyl)-1H-imidazole
CAS 852525-32-7C17H16N2O2
5-(4-Methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-imidazole chemical structure, C19H20N2O4, CAS 852525-33-8
5-(4-Methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-imidazole
CAS 852525-33-8C19H20N2O4
N-(1,1-Dimethylethyl)-4-[5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl]benzenesulfonamide chemical structure, C20H22FN3O3S, CAS 499777-84-3
N-(1,1-Dimethylethyl)-4-[5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl]benzenesulfonamide
CAS 499777-84-3C20H22FN3O3S
5-(p-Nitrophenyl)-1-phenylimidazole chemical structure, C15H11N3O2, CAS 61278-54-4
5-(p-Nitrophenyl)-1-phenylimidazole
CAS 61278-54-4C15H11N3O2
1-(4-Nitrophenyl)-5-phenyl-1H-imidazole chemical structure, C15H11N3O2, CAS 61278-55-5
1-(4-Nitrophenyl)-5-phenyl-1H-imidazole
CAS 61278-55-5C15H11N3O2
1,5-Bis(4-nitrophenyl)-1H-imidazole chemical structure, C15H10N4O4, CAS 61278-56-6
1,5-Bis(4-nitrophenyl)-1H-imidazole
CAS 61278-56-6C15H10N4O4
1,5-Bis(4-chlorophenyl)-1H-imidazole chemical structure, C15H10Cl2N2, CAS 61278-57-7
1,5-Bis(4-chlorophenyl)-1H-imidazole
CAS 61278-57-7C15H10Cl2N2
5-(4-Methylphenyl)-1-phenyl-1H-imidazole chemical structure, C16H14N2, CAS 61278-59-9
5-(4-Methylphenyl)-1-phenyl-1H-imidazole
CAS 61278-59-9C16H14N2
4-Methyl-1-(4-nitrophenyl)-5-phenyl-1H-imidazole chemical structure, C16H13N3O2, CAS 61278-78-2
4-Methyl-1-(4-nitrophenyl)-5-phenyl-1H-imidazole
CAS 61278-78-2C16H13N3O2
Methyl 1,5-diphenyl-1H-imidazole-4-carboxylate chemical structure, C17H14N2O2, CAS 130740-25-9
Methyl 1,5-diphenyl-1H-imidazole-4-carboxylate
CAS 130740-25-9C17H14N2O2
2-((1,5-Diphenyl-1H-imidazol-2-yl)thio)acetonitrile chemical structure, C17H13N3S, CAS 903790-64-7
2-((1,5-Diphenyl-1H-imidazol-2-yl)thio)acetonitrile
CAS 903790-64-7C17H13N3S
2-((1-(3-Methoxyphenyl)-5-phenyl-1H-imidazol-2-yl)thio)acetonitrile chemical structure, C18H15N3OS, CAS 871212-04-3
2-((1-(3-Methoxyphenyl)-5-phenyl-1H-imidazol-2-yl)thio)acetonitrile
CAS 871212-04-3C18H15N3OS
2-(Methylthio)-1,5-diphenyl-1H-imidazole chemical structure, C16H14N2S, CAS 136802-80-7
2-(Methylthio)-1,5-diphenyl-1H-imidazole
CAS 136802-80-7C16H14N2S
2-{[1-(3-Chlorophenyl)-5-phenyl-1H-imidazol-2-yl]sulfanyl}acetonitrile chemical structure, C17H12ClN3S, CAS 1014571-03-9
2-{[1-(3-Chlorophenyl)-5-phenyl-1H-imidazol-2-yl]sulfanyl}acetonitrile
CAS 1014571-03-9C17H12ClN3S