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Murcko scaffold

Ring system with 4 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
12
With full pages
7
Scaffold SMILES

C1=Cc2c(ccc3c2OCC(c2ccccc2)C3)OC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=Cc2c(ccc3c2OCC(c2ccccc2)C3)OC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Glabridin chemical structure, C20H20O4, CAS 59870-68-7
Glabridin
CAS 59870-68-7C20H20O4
Hispaglabridin A chemical structure, C25H28O4, CAS 68978-03-0
Hispaglabridin A
CAS 68978-03-0C25H28O4
Heminitidulan chemical structure, C26H30O4, CAS 66446-90-0
Heminitidulan
CAS 66446-90-0C26H30O4
Nitidulin chemical structure, C26H30O5, CAS 66446-87-5
Nitidulin
CAS 66446-87-5C26H30O5
Npc82997 chemical structure, C20H20O4, CAS 850582-15-9
Npc82997
CAS 850582-15-9C20H20O4
4'-O-Methylglabridin chemical structure, C21H22O4, CAS 68978-09-6
4'-O-Methylglabridin
CAS 68978-09-6C21H22O4
3'-Hydroxy-4'-O-methylglabridin chemical structure, C21H22O5, CAS 175554-11-7
3'-Hydroxy-4'-O-methylglabridin
CAS 175554-11-7C21H22O5
3'-Methoxyglabradin chemical structure, C21H22O5, CAS 74046-05-2
3'-Methoxyglabradin
CAS 74046-05-2C21H22O5
4'-O-Methylglabridin, (S)- chemical structure, C21H22O4, CAS 105119-61-7
4'-O-Methylglabridin, (S)-
CAS 105119-61-7C21H22O4
4-[(3S)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]resorcinol chemical structure, C20H20O4, CAS 872596-23-1
4-[(3S)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]resorcinol
CAS 872596-23-1C20H20O4
Glyasperin H chemical structure, C22H24O5, CAS 145382-63-4
Glyasperin H
CAS 145382-63-4C22H24O5
3-(2,4-Dimethoxyphenyl)-8,8-dimethyl-3,4-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran chemical structure, C22H24O4, CAS 850582-12-6
3-(2,4-Dimethoxyphenyl)-8,8-dimethyl-3,4-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran
CAS 850582-12-6C22H24O4