Murcko scaffold
Ring system with 5 rings and 19 atoms
519 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 19
- Chemicals
- 519
- With full pages
- 31
Scaffold SMILES
c1ccc2c(CC3CC4CCN3CC4)ccnc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 433 to 480 of 519 chemicals
Quinine, 5-amino-
CAS 904817-75-0C20H25N3O2
![Cinchonan-9-ol, 11-[(2-aminoethyl)thio]-10,11-dihydro-6a(2)-methoxy-, 9-[N-(1,1-dimethylethyl)carbamate], (8I+/-,9R)- chemical structure, C27H40N4O3S, CAS 860645-81-4](/s/GTDLYSXKRLCPEK-QXVOXHNYSA-N.svg)
Cinchonan-9-ol, 11-[(2-aminoethyl)thio]-10,11-dihydro-6a(2)-methoxy-, 9-[N-(1,1-dimethylethyl)carbamate], (8I+/-,9R)-
CAS 860645-81-4C27H40N4O3S
9,10-Dihydrocinchonidine monohydrochloride
CAS 183232-84-0C19H25ClN2O
tert-Butyl ((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)carbamate
CAS 200944-00-9C25H33N3O3
(S)-((2R,4S,5R)-5-Ethenyl-1-azabicyclo(2.2.2)oct-2-yl)(6-aminoquinolin-4-yl)methanol
CAS 2143936-31-4C19H23N3O
Hydroquinine-2'-carboxylic acid, methyl ester
C22H28N2O4
Cinchonan-9-ol, 10,11-dihydro-6a(2)-methoxy-, hydrochloride (1:2), (1I(2),4I(2),9S)-(A+/-)-
CAS 40542-76-5C20H28Cl2N2O2
6-Carboxyl-4-phenyl-3,4-dihydrocoumarin Cinchonidine Salt
CAS 380636-40-8C35H34N2O5
![N-tert-Butyl-2-[(1S)-5-ethenyl-2-[hydroxy(quinolin-4-yl)methyl]-1-azoniabicyclo[2.2.2]octan-1-yl]acetamide bromide chemical structure, C25H34BrN3O2](/s/GBDTVCZRQRNYGD-YVHUEZMPSA-N.svg)
N-tert-Butyl-2-[(1S)-5-ethenyl-2-[hydroxy(quinolin-4-yl)methyl]-1-azoniabicyclo[2.2.2]octan-1-yl]acetamide bromide
C25H34BrN3O2
(1S,2S,4S,5R)-2-((S)-Isothiocyanato(quinolin-4-yl)methyl)-5-vinylquinuclidine
CAS 1639342-81-6C20H21N3S
Epiquinine, copper complex
CAS 128240-62-0C40H46CuN4O4
Quinine, Ag complex
CAS 128947-53-5C20H23AgN2O2
(1S,2R,4S,5R)-1-(2-(tert-Butylamino)-2-oxoethyl)-2-((S)-hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide
CAS 2937392-08-8C25H34BrN3O2
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, hydriodide sulfate (salt) (4:2:3), hexahydrate
CAS 6119-84-2C80H116I2N8O26S3
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, hydriodide sulfate (salt) (4:2:3)
CAS 6119-57-9C60H80I2N6O18S3
Quinine, hexakis(isothiocyanato)chromate(3-) (3:2), dihydrate
CAS 33194-98-8C72H82Cr2N18O8S12
Quinine, hexacyanoferrate(4-)(1:1), heptahydrate
CAS 12001-93-3C26H42FeN8O9
1-Hexadecanesulfonic acid, quinine salt (4:1)
CAS 120968-65-2C84H160N2O14S4
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, (OC-6-11)-tetrakis(cyano-C)ferrate(4-) (4:1)
CAS 12001-92-2C86H96FeN14O8-4
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, hydrochloride sulfate (salt) (2:2:1), trihydrate
CAS 6119-51-3C40H58Cl2N4O11S
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, hydrochloride sulfate (salt) (2:2:1)
CAS 1555-55-1C40H52Cl2N4O8S
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, hydrochloride, phosphate (2:1:2) (salt)
CAS 652-91-5C40H55ClN4O12P2
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, selenate (2:1) (salt), dihydrate
CAS 60411-17-8C40H52N4O9Se
Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9S)-, sulfate (2:1)
C40H50N4O8S
- Cinchonan-9-ol, 6a(2)-methoxy-, (6I+/-,9R)-, [1,1a(2)-biphenyl]-2,2a(2)-dicarboxylate (2:1) (salt)107927-77-5C54H58N4O8
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, 2-hydroxy-1,2,3-propanetricarboxylate (2:1) (salt), heptahydrate6151-66-2C46H70N4O18
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, ethanedioate (2:1) (salt), hexahydrate6119-61-5C42H62N4O14
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, phosphate (2:1) (salt), octahydrate6119-63-7C40H67N4O16P
- Acetic acid, trichloro-, quinine salt (2:1)123006-03-1C24H26Cl6N2O6
- Cinchonan-9-ol, 10,11-dihydro-6a(2)-methoxy-, (8I+/-,9R)-, sulfate (2:1) (salt), hexahydrate6168-81-6C40H56N4O9S
- Cinchonan-9-ol, 10,11-dihydro-6a(2)-methoxy-, (8I+/-,9R)-, sulfate (2:1) (salt), tetrahydrate6168-80-5C40H62N4O12S
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, rel-(1R,3S)-1,2,2-trimethyl-1,3-cyclopentanedicarboxylate (2:1)549-57-5C50H64N4O8
- Quinine, (+)-4,4a(2)-azobis[4-cyanovalerate] (2:1)23886-48-8C52H64N8O8
- Quinine, hydrochloride (2:1)30860-23-2C40H49ClN4O4
- 1-Tetradecanesulfonic acid, quinine salt (2:1)120858-01-7C48H84N2O8S2
- Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-8-nitro-2,6-dioxo-, quinine salt (2:1)120334-36-3C38H42N12O14
- Purine-7-acetic acid, 8-bromo-1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, quinine salt (2:1)120858-11-9C38H42Br2N10O10
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, trans-1,2-cyclobutanedicarboxylate (2:1) (salt)36672-46-5C46H56N4O8
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9S)-, [1,1a(2)-biphenyl]-2,2a(2)-dicarboxylate (2:1) (salt), monohydrate130195-77-6C54H60N4O9
- Purine-7-acetic acid, 8-chloro-1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, quinine salt (2:1)120858-12-0C38H42Cl2N10O10
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, ethanedioate (2:1) (salt)549-58-6C42H50N4O8
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, 3,3a(2)-dimethyl[1,1a(2)-biphenyl]-2,2a(2)-dicarboxylate (2:1) (salt)106802-72-6C56H62N4O8
- Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, quinine salt (2:1)120334-38-5C38H44N10O10
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)549-61-1C44H54N4O10
- 1-Dodecanesulfonic acid, quinine salt (2:1)120968-63-0C44H76N2O8S2
- Cinchonan-9-thiol, 6a(2)-methoxy-, hydrogen sulfate (ester), (8I+/-,9S)-, thiosulfate (2:1)49557-41-7C40H50N4O11S6
- Cinchonan-9-ol, 6a(2)-methoxy-, (8I+/-,9R)-, sulfate (1:2) (salt)20317-85-5C20H28N2O10S2
- Cinchonan-9-ol, 6a(2)-methoxy-, dihydriodide, pentahydrate, (8I+/-,9R)-6484-75-9C20H27IN2O3