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Murcko scaffold

Ring system with 5 rings and 19 atoms

519 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
19
Chemicals
519
With full pages
80
Scaffold SMILES

c1ccc2c(CC3CC4CCN3CC4)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(CC3CC4CCN3CC4)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 519 chemicals

(1S)-N-Diethoxyphosphoryl-1-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-1-quinolin-4-ylmethanamine chemical structure, C23H32N3O3P
(1S)-N-Diethoxyphosphoryl-1-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-1-quinolin-4-ylmethanamine
C23H32N3O3P
(1S)-N-Diethoxyphosphoryl-1-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-1-(6-methoxyquinolin-4-yl)methanamine chemical structure, C24H34N3O4P
(1S)-N-Diethoxyphosphoryl-1-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-1-(6-methoxyquinolin-4-yl)methanamine
C24H34N3O4P
4-[(R)-Amino-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]methyl]quinolin-6-ol chemical structure, C19H25N3O, CAS 1430820-98-6
4-[(R)-Amino-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]methyl]quinolin-6-ol
CAS 1430820-98-6C19H25N3O
(1R,4R,5R)-3-Oxo-2-oxabicyclo[2.2.1]heptane-5-carboxylic acid cinchonidine salt chemical structure, C26H30N2O5, CAS 1233219-43-6
(1R,4R,5R)-3-Oxo-2-oxabicyclo[2.2.1]heptane-5-carboxylic acid cinchonidine salt
CAS 1233219-43-6C26H30N2O5
(9R)-10,11-Dihydrocinchonan-9-amine chemical structure, C19H25N3, CAS 354532-49-3
(9R)-10,11-Dihydrocinchonan-9-amine
CAS 354532-49-3C19H25N3
Bis((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol) sulfate dihydrate chemical structure, C40H54N4O10S
Bis((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol) sulfate dihydrate
C40H54N4O10S
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl 2,2-dimethylpropanoate chemical structure, C25H32N2O3, CAS 60809-28-1
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl 2,2-dimethylpropanoate
CAS 60809-28-1C25H32N2O3
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl dodecanoate chemical structure, C32H46N2O3, CAS 916429-53-3
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl dodecanoate
CAS 916429-53-3C32H46N2O3
[(4S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol, dihydrate, hydrochloride chemical structure, C20H29ClN2O4
[(4S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol, dihydrate, hydrochloride
C20H29ClN2O4
4-[(5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-hydroxymethyl]quinolin-6-ol, hydrochloride chemical structure, C19H23ClN2O2, CAS 72436-12-5
4-[(5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-hydroxymethyl]quinolin-6-ol, hydrochloride
CAS 72436-12-5C19H23ClN2O2
Bis((5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol), sulfuric acid, tetrahydrate chemical structure, C40H58N4O12S, CAS 1108745-57-8
Bis((5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol), sulfuric acid, tetrahydrate
CAS 1108745-57-8C40H58N4O12S
4-[[(2S)-1-Azabicyclo[2.2.2]octan-2-yl]methyl]quinoline chemical structure, C17H20N2, CAS 6883-26-7
4-[[(2S)-1-Azabicyclo[2.2.2]octan-2-yl]methyl]quinoline
CAS 6883-26-7C17H20N2
(9R)-6'-Cinchonan-9-amine Trihydrochloride chemical structure, C19H26Cl3N3, CAS 168960-94-9
(9R)-6'-Cinchonan-9-amine Trihydrochloride
CAS 168960-94-9C19H26Cl3N3
(1S)-Quinolin-4-yl(5-vinylquinuclidin-2-yl)methyl acetate chemical structure, C21H24N2O2
(1S)-Quinolin-4-yl(5-vinylquinuclidin-2-yl)methyl acetate
C21H24N2O2
Orb1300601 chemical structure, C20H29ClN2O4
Orb1300601
C20H29ClN2O4
(8alpha, 9R)-10,11-Dihydro-6'-methoxycinchonan-9-amine trihydrochloride chemical structure, C20H30Cl3N3O, CAS 931098-92-9
(8alpha, 9R)-10,11-Dihydro-6'-methoxycinchonan-9-amine trihydrochloride
CAS 931098-92-9C20H30Cl3N3O
[[(2S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethyl] acetate chemical structure, C21H24N2O2
[[(2S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethyl] acetate
C21H24N2O2
(R)-((1S,2S,4S,5R)-5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanamine chemical structure, C19H25N3, CAS 322765-61-7
(R)-((1S,2S,4S,5R)-5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanamine
CAS 322765-61-7C19H25N3
Quinine sulfate dihydrate chemical structure, C20H34N2O10S
Quinine sulfate dihydrate
C20H34N2O10S
Phenobarbital quinine chemical structure, C32H36N4O5, CAS 880258-50-4
Phenobarbital quinine
CAS 880258-50-4C32H36N4O5
Benzylpenicillin quinine chemical structure, C36H42N4O6S, CAS 696628-37-2
Benzylpenicillin quinine
CAS 696628-37-2C36H42N4O6S
(9R)-9-{[tert-Butyl(dimethyl)silyl]oxy}-11-iodo-6'-methoxy-8alpha-10,11-dihydrocinchonan chemical structure, C26H39IN2O2Si, CAS 194983-30-7
(9R)-9-{[tert-Butyl(dimethyl)silyl]oxy}-11-iodo-6'-methoxy-8alpha-10,11-dihydrocinchonan
CAS 194983-30-7C26H39IN2O2Si
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl 3,7,11-trimethyldodeca-2,6,10-trien-1-yl carbonate chemical structure, C36H48N2O4, CAS 42976-78-3
(9R)-6'-Methoxy-8alpha-cinchonan-9-yl 3,7,11-trimethyldodeca-2,6,10-trien-1-yl carbonate
CAS 42976-78-3C36H48N2O4
(2E)-3,7-Dimethylocta-2,6-dien-1-yl (9R)-6'-methoxy-8alpha-cinchonan-9-yl carbonate chemical structure, C31H40N2O4, CAS 42512-01-6
(2E)-3,7-Dimethylocta-2,6-dien-1-yl (9R)-6'-methoxy-8alpha-cinchonan-9-yl carbonate
CAS 42512-01-6C31H40N2O4