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Murcko scaffold

Ring system with 4 rings and 29 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(c1cccc(S(=O)(=O)N2CCCCC2)c1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cccc(S(=O)(=O)N2CCCCC2)c1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Methyl-3-(piperidylsulfonyl)phenyl 4-phenylpiperazinyl ketone chemical structure, C23H29N3O3S, CAS 420832-25-3
4-Methyl-3-(piperidylsulfonyl)phenyl 4-phenylpiperazinyl ketone
CAS 420832-25-3C23H29N3O3S
(4-(3-Chlorophenyl)piperazin-1-yl)(3-(piperidin-1-ylsulfonyl)phenyl)methanone chemical structure, C22H26ClN3O3S, CAS 638135-84-9
(4-(3-Chlorophenyl)piperazin-1-yl)(3-(piperidin-1-ylsulfonyl)phenyl)methanone
CAS 638135-84-9C22H26ClN3O3S
[4-(4-Fluorophenyl)piperazin-1-yl]-(4-methyl-3-piperidin-1-ylsulfonylphenyl)methanone chemical structure, C23H28FN3O3S, CAS 690246-84-5
[4-(4-Fluorophenyl)piperazin-1-yl]-(4-methyl-3-piperidin-1-ylsulfonylphenyl)methanone
CAS 690246-84-5C23H28FN3O3S
4-(3-Chlorophenyl)piperazinyl 4-methyl-3-(piperidylsulfonyl)phenyl ketone chemical structure, C23H28ClN3O3S, CAS 690246-76-5
4-(3-Chlorophenyl)piperazinyl 4-methyl-3-(piperidylsulfonyl)phenyl ketone
CAS 690246-76-5C23H28ClN3O3S
4-(2-Fluorophenyl)piperazinyl 3-(piperidylsulfonyl)phenyl ketone chemical structure, C22H26FN3O3S, CAS 561007-65-6
4-(2-Fluorophenyl)piperazinyl 3-(piperidylsulfonyl)phenyl ketone
CAS 561007-65-6C22H26FN3O3S
(4-Chloro-3-(piperidin-1-ylsulfonyl)phenyl)(4-(4-fluorophenyl)piperazin-1-yl)methanone chemical structure, C22H25ClFN3O3S, CAS 838884-95-0
(4-Chloro-3-(piperidin-1-ylsulfonyl)phenyl)(4-(4-fluorophenyl)piperazin-1-yl)methanone
CAS 838884-95-0C22H25ClFN3O3S
(4-Chloro-3-(piperidin-1-ylsulfonyl)phenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone chemical structure, C22H25ClFN3O3S, CAS 850625-80-8
(4-Chloro-3-(piperidin-1-ylsulfonyl)phenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone
CAS 850625-80-8C22H25ClFN3O3S