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Murcko scaffold

Ring system with 4 rings and 26 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
11
With full pages
3
Scaffold SMILES

c1ccc(Oc2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

WZ-3146 chemical structure, C24H25ClN6O2, CAS 1214265-56-1
WZ-3146
CAS 1214265-56-1C24H25ClN6O2
WZ-4002 chemical structure, C25H27ClN6O3, CAS 1213269-23-8
WZ-4002
CAS 1213269-23-8C25H27ClN6O3
[4-(3-Methyl-4-nitro-phenoxy)-pyrimidin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine chemical structure, C22H24N6O3, CAS 853299-41-9
[4-(3-Methyl-4-nitro-phenoxy)-pyrimidin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine
CAS 853299-41-9C22H24N6O3
[4-(4-Amino-3-methyl-phenoxy)-pyrimidin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine chemical structure, C22H26N6O, CAS 853299-40-8
[4-(4-Amino-3-methyl-phenoxy)-pyrimidin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine
CAS 853299-40-8C22H26N6O
4-(4-Aminophenoxy)-5-chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine chemical structure, C21H23ClN6O, CAS 1254783-92-0
4-(4-Aminophenoxy)-5-chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine
CAS 1254783-92-0C21H23ClN6O
5-Chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(4-nitrophenoxy)pyrimidin-2-amine chemical structure, C21H21ClN6O3, CAS 1254783-91-9
5-Chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(4-nitrophenoxy)pyrimidin-2-amine
CAS 1254783-91-9C21H21ClN6O3
4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine chemical structure, C22H25ClN6O2, CAS 1213269-26-1
4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine
CAS 1213269-26-1C22H25ClN6O2
5-Chloro-N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(3-nitrophenoxy)pyrimidin-2-amine chemical structure, C22H23ClN6O4, CAS 1213269-25-0
5-Chloro-N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(3-nitrophenoxy)pyrimidin-2-amine
CAS 1213269-25-0C22H23ClN6O4
N-(3-((5-Chloro-2-((2-methoxy-4-(4-methyl-1-piperazinyl)phenyl)amino)-4-pyrimidinyl)oxy)phenyl)propanamide chemical structure, C25H29ClN6O3, CAS 1214265-58-3
N-(3-((5-Chloro-2-((2-methoxy-4-(4-methyl-1-piperazinyl)phenyl)amino)-4-pyrimidinyl)oxy)phenyl)propanamide
CAS 1214265-58-3C25H29ClN6O3
WZ4002 Dihydrobromide chemical structure, C25H29Br2ClN6O3, CAS 2308095-38-5
WZ4002 Dihydrobromide
CAS 2308095-38-5C25H29Br2ClN6O3
WZ4002 hydrobromide chemical structure, C25H28BrClN6O3, CAS 2109295-53-4
WZ4002 hydrobromide
CAS 2109295-53-4C25H28BrClN6O3