Murcko scaffold
2-(Phenylmethyl)oxirane scaffold
476 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 476
- With full pages
- 14
Scaffold SMILES
c1ccc(CC2CO2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 476 chemicals
2-Fluoro-2-((4-methoxyphenyl)methyl)oxirane
CAS 175399-99-2C10H11FO2
![2-{[4-(Propan-2-yl)phenyl]methyl}oxirane chemical structure, C12H16O, CAS 62826-27-1](/s/NGXLBOQJHDRHLD-UHFFFAOYSA-N.svg)
2-{[4-(Propan-2-yl)phenyl]methyl}oxirane
CAS 62826-27-1C12H16O
Methyl 3-benzyl-3-methyloxirane-2-carboxylate
CAS 57734-32-4C12H14O3
(2S)-2-Benzyl-2-methyloxirane
CAS 658063-43-5C10H12O
![(2R)-2-[(S)-Fluoro(phenyl)methyl]oxirane chemical structure, C9H9FO, CAS 923012-74-2](/s/KDCLZRHLDRBQFC-BDAKNGLRSA-N.svg)
(2R)-2-[(S)-Fluoro(phenyl)methyl]oxirane
CAS 923012-74-2C9H9FO
![(2S)-2-[(R)-Fluoro(phenyl)methyl]oxirane chemical structure, C9H9FO, CAS 865864-66-0](/s/KDCLZRHLDRBQFC-DTWKUNHWSA-N.svg)
(2S)-2-[(R)-Fluoro(phenyl)methyl]oxirane
CAS 865864-66-0C9H9FO
![(2S)-2-[(S)-Fluoro(phenyl)methyl]oxirane chemical structure, C9H9FO, CAS 923012-75-3](/s/KDCLZRHLDRBQFC-IUCAKERBSA-N.svg)
(2S)-2-[(S)-Fluoro(phenyl)methyl]oxirane
CAS 923012-75-3C9H9FO
![(2R)-2-[(R)-Fluoro(phenyl)methyl]oxirane chemical structure, C9H9FO, CAS 923012-76-4](/s/KDCLZRHLDRBQFC-RKDXNWHRSA-N.svg)
(2R)-2-[(R)-Fluoro(phenyl)methyl]oxirane
CAS 923012-76-4C9H9FO
![2-[(2-tert-Butylphenyl)methyl]oxirane chemical structure, C13H18O, CAS 2228399-94-6](/s/HCJLKUPUSMADED-UHFFFAOYSA-N.svg)
2-[(2-tert-Butylphenyl)methyl]oxirane
CAS 2228399-94-6C13H18O
![2-[(2-Ethenylphenyl)methyl]oxirane chemical structure, C11H12O, CAS 63338-09-0](/s/ASYDHHZLJPHNJY-UHFFFAOYSA-N.svg)
2-[(2-Ethenylphenyl)methyl]oxirane
CAS 63338-09-0C11H12O
![2-[(Oxiran-2-yl)methyl]benzonitrile chemical structure, C10H9NO, CAS 2228782-61-2](/s/RPLKECGWNRCISO-UHFFFAOYSA-N.svg)
2-[(Oxiran-2-yl)methyl]benzonitrile
CAS 2228782-61-2C10H9NO
![2-[(2,3-Dimethylphenyl)methyl]oxirane chemical structure, C11H14O, CAS 1602388-06-6](/s/HBBGAESXDKCELE-UHFFFAOYSA-N.svg)
2-[(2,3-Dimethylphenyl)methyl]oxirane
CAS 1602388-06-6C11H14O
![2-[1-(4-Fluorophenyl)ethyl]oxirane chemical structure, C10H11FO, CAS 2228647-33-2](/s/HZDLOFNHYFIFIN-UHFFFAOYSA-N.svg)
2-[1-(4-Fluorophenyl)ethyl]oxirane
CAS 2228647-33-2C10H11FO
![2-[(2-Ethoxyphenyl)methyl]oxirane chemical structure, C11H14O2, CAS 62826-29-3](/s/YNMIPOBEIANVDW-UHFFFAOYSA-N.svg)
2-[(2-Ethoxyphenyl)methyl]oxirane
CAS 62826-29-3C11H14O2
2-Benzyl-3-ethyl-2,3-dimethyloxirane
CAS 92511-27-8C13H18O
![2-[(4-tert-Butylphenyl)methyl]oxirane chemical structure, C13H18O, CAS 18458-02-1](/s/DMDXNNDPNUMUMT-UHFFFAOYSA-N.svg)
2-[(4-tert-Butylphenyl)methyl]oxirane
CAS 18458-02-1C13H18O
![Methyl 4-[(oxiran-2-yl)methyl]benzoate chemical structure, C11H12O3, CAS 49574-52-9](/s/BVZNJNCYMCJEEY-UHFFFAOYSA-N.svg)
Methyl 4-[(oxiran-2-yl)methyl]benzoate
CAS 49574-52-9C11H12O3
![2-[(4-Ethylphenyl)methyl]oxirane chemical structure, C11H14O, CAS 62826-24-8](/s/ITOJQTFMOWSKDG-UHFFFAOYSA-N.svg)
2-[(4-Ethylphenyl)methyl]oxirane
CAS 62826-24-8C11H14O
![2-[(2,5-Dimethoxyphenyl)methyl]oxirane chemical structure, C11H14O3, CAS 1026729-16-7](/s/YRZOAJFPWKSMIS-UHFFFAOYSA-N.svg)
2-[(2,5-Dimethoxyphenyl)methyl]oxirane
CAS 1026729-16-7C11H14O3
![(2R)-2-[(2,4,5-Trifluorophenyl)methyl]oxirane chemical structure, C9H7F3O, CAS 2227918-11-6](/s/BJVWCGAQMZQCGP-ZCFIWIBFSA-N.svg)
(2R)-2-[(2,4,5-Trifluorophenyl)methyl]oxirane
CAS 2227918-11-6C9H7F3O
![(2S)-2-[(2,4,5-Trifluorophenyl)methyl]oxirane chemical structure, C9H7F3O, CAS 1283096-72-9](/s/BJVWCGAQMZQCGP-LURJTMIESA-N.svg)
(2S)-2-[(2,4,5-Trifluorophenyl)methyl]oxirane
CAS 1283096-72-9C9H7F3O
![2-{[2-(Methylsulfanyl)phenyl]methyl}oxirane chemical structure, C10H12OS, CAS 2137979-52-1](/s/GWHFMDYEKTWZMO-UHFFFAOYSA-N.svg)
2-{[2-(Methylsulfanyl)phenyl]methyl}oxirane
CAS 2137979-52-1C10H12OS
![2-[(2,4-Dimethylphenyl)methyl]oxirane chemical structure, C11H14O, CAS 1552600-23-3](/s/BPEZXLIHHKEPEZ-UHFFFAOYSA-N.svg)
2-[(2,4-Dimethylphenyl)methyl]oxirane
CAS 1552600-23-3C11H14O
![N-{4-[(Oxiran-2-yl)methyl]phenyl}acetamide chemical structure, C11H13NO2, CAS 606493-56-5](/s/QUYFJYMVGJPHNH-UHFFFAOYSA-N.svg)
N-{4-[(Oxiran-2-yl)methyl]phenyl}acetamide
CAS 606493-56-5C11H13NO2
- 2-[(2-Chloro-6-nitrophenyl)methyl]oxirane2229278-69-5C9H8ClNO3
- 2-[(4-Methoxy-3-methylphenyl)methyl]oxirane2229436-13-7C11H14O2
- 2-[(3-Fluoro-4-methoxyphenyl)methyl]oxirane222422-49-3C10H11FO2
- 2-[(2,5-Dichlorophenyl)methyl]oxirane1546183-31-6C9H8Cl2O
- 2-[(2,6-Dichlorophenyl)methyl]oxirane2137917-27-0C9H8Cl2O
- 4-[(Oxiran-2-yl)methyl]benzonitrile854690-79-2C10H9NO
- 2-[(2,4,6-Trichlorophenyl)methyl]oxirane23282-02-2C9H7Cl3O
- 2-[(3-tert-Butylphenyl)methyl]oxirane2229187-51-1C13H18O
- 2-[(2,3-Dimethoxyphenyl)methyl]oxirane2138207-10-8C11H14O3
- 2-{[2-(Propan-2-yl)phenyl]methyl}oxirane1865112-45-3C12H16O
- 2-{[4-(Trifluoromethyl)phenyl]methyl}oxirane1423025-87-9C10H9F3O
- 2-[(2,6-Dimethylphenyl)methyl]oxirane93351-08-7C11H14O
- 4-[(Oxiran-2-yl)methyl]benzoic acid1824444-36-1C10H10O3
- 2-([3-(Trifluoromethyl)phenyl]methyl)oxirane713-71-3C10H9F3O
- 2-[(2-Ethylphenyl)methyl]oxirane62826-23-7C11H14O
- 2-{[2-(Prop-2-en-1-yl)phenyl]methyl}oxirane52210-99-8C12H14O
- 2-[(2,3,4,5,6-Pentafluorophenyl)methyl]oxirane32974-30-4C9H5F5O
- 2-((2,4-Dichlorophenyl)methyl)oxirane1879281-48-7C9H8Cl2O
- 4-[(Oxiran-2-yl)methyl]benzene-1,2-diol62600-15-1C9H10O3
- 2-(2-Methoxybenzyl)-2-methyloxirane1342511-93-6C11H14O2
- 2-(4-Methoxybenzyl)-2-methyloxirane1342092-99-2C11H14O2
- Methyl 3-benzyl-2,3-dimethyloxirane-2-carboxylate1515266-58-6C13H16O3
- 2-[Bromo(phenyl)methyl]-3-methyloxirane142052-62-8C10H11BrO
- 2-{[4-(Heptafluoropropyl)phenyl]methyl}oxirane144006-68-8C12H9F7O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CC2)cc1130 chemicals
c1ccc(OC2CC2)cc157 chemicals
O=C(c1ccccc1)C1CC128 chemicals
c1ccc(NC2CC2)cc120 chemicals
c1ccc(SC2CC2)cc114 chemicals
C1COCC(CC2CO2)C111 chemicals
O=S(=O)(c1ccccc1)C1CC110 chemicals
c1ccc(NC2CC2)nc110 chemicals
C1CCN(CC2CC2)CC19 chemicals
O=C(C1CC1)N1CCNCC17 chemicals
c1cncc(OC2CC2)c17 chemicals
C1CC(NC2CC2)CCN17 chemicals