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Murcko scaffold

Ring system with 3 rings and 17 atoms

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
55
With full pages
10
Scaffold SMILES

O=C1CC(c2ccccc2)Cc2ncncc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2ccccc2)Cc2ncncc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

2-Amino-7-(2,4-dimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C16H17N3O3, CAS 848753-19-5
2-Amino-7-(2,4-dimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 848753-19-5C16H17N3O3
7-[4-(Dimethylamino)phenyl]-2-{[3-(propan-2-yloxy)propyl]amino}-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H30N4O2, CAS 669750-95-2
7-[4-(Dimethylamino)phenyl]-2-{[3-(propan-2-yloxy)propyl]amino}-7,8-dihydroquinazolin-5(6H)-one
CAS 669750-95-2C22H30N4O2
2-[(3-Ethoxypropyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H25N3O2, CAS 669750-25-8
2-[(3-Ethoxypropyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 669750-25-8C20H25N3O2
2-Amino-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C15H15N3O2, CAS 354767-74-1
2-Amino-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 354767-74-1C15H15N3O2
2-Amino-7-(4-chlorophenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C14H12ClN3O, CAS 299934-41-1
2-Amino-7-(4-chlorophenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 299934-41-1C14H12ClN3O
2-Amino-7-phenyl-7,8-dihydro-6H-quinazolin-5-one chemical structure, C14H13N3O, CAS 6075-47-4
2-Amino-7-phenyl-7,8-dihydro-6H-quinazolin-5-one
CAS 6075-47-4C14H13N3O
N-(5-Oxo-7-phenyl-7,8-dihydro-6H-quinazolin-2-yl)acetamide chemical structure, C16H15N3O2, CAS 312626-61-2
N-(5-Oxo-7-phenyl-7,8-dihydro-6H-quinazolin-2-yl)acetamide
CAS 312626-61-2C16H15N3O2
N-[7-(2-Chlorophenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide chemical structure, C16H14ClN3O2, CAS 351163-42-3
N-[7-(2-Chlorophenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide
CAS 351163-42-3C16H14ClN3O2
N-[7-(4-Methylphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide chemical structure, C17H17N3O2, CAS 354538-17-3
N-[7-(4-Methylphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide
CAS 354538-17-3C17H17N3O2
2-Amino-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C15H15N3O, CAS 354538-15-1
2-Amino-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 354538-15-1C15H15N3O
2-Amino-7-(3-chlorophenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C14H12ClN3O, CAS 351163-39-8
2-Amino-7-(3-chlorophenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 351163-39-8C14H12ClN3O
2-Amino-7-(3,4-dimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C16H17N3O3, CAS 351163-43-4
2-Amino-7-(3,4-dimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 351163-43-4C16H17N3O3
N-[7-(4-Chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide chemical structure, C16H14ClN3O2, CAS 374545-65-0
N-[7-(4-Chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide
CAS 374545-65-0C16H14ClN3O2
N-[7-(4-Methylphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]propanamide chemical structure, C18H19N3O2, CAS 354538-18-4
N-[7-(4-Methylphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]propanamide
CAS 354538-18-4C18H19N3O2
2-Amino-7-(3,4,5-trimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C17H19N3O4, CAS 364380-99-4
2-Amino-7-(3,4,5-trimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 364380-99-4C17H19N3O4
N-[5-Oxo-7-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide chemical structure, C19H21N3O5, CAS 364609-48-3
N-[5-Oxo-7-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide
CAS 364609-48-3C19H21N3O5
N-[7-(4-tert-Butylphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide chemical structure, C20H23N3O2, CAS 523990-63-8
N-[7-(4-tert-Butylphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide
CAS 523990-63-8C20H23N3O2
2-Amino-7-(4-tert-butylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H21N3O, CAS 523990-62-7
2-Amino-7-(4-tert-butylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 523990-62-7C18H21N3O
N-[7-(3,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]-2-ethylbutanamide chemical structure, C22H27N3O4, CAS 838269-99-1
N-[7-(3,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]-2-ethylbutanamide
CAS 838269-99-1C22H27N3O4
N-{7-[4-(Dimethylamino)phenyl]-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl}propanamide chemical structure, C19H22N4O2, CAS 727373-10-6
N-{7-[4-(Dimethylamino)phenyl]-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl}propanamide
CAS 727373-10-6C19H22N4O2
N-[7-(3-Chlorophenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide chemical structure, C16H14ClN3O2, CAS 351163-40-1
N-[7-(3-Chlorophenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide
CAS 351163-40-1C16H14ClN3O2
N-[7-(4-Methoxyphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide chemical structure, C17H17N3O3, CAS 351163-44-5
N-[7-(4-Methoxyphenyl)-5-oxo-7,8-dihydro-6H-quinazolin-2-yl]acetamide
CAS 351163-44-5C17H17N3O3
N-[7-(2,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide chemical structure, C18H19N3O4, CAS 858766-63-9
N-[7-(2,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide
CAS 858766-63-9C18H19N3O4
N-[7-(2,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]propanamide chemical structure, C19H21N3O4, CAS 858758-18-6
N-[7-(2,4-Dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]propanamide
CAS 858758-18-6C19H21N3O4