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Murcko scaffold

Ring system with 4 rings and 24 atoms

39 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
39
With full pages
6
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

(9H-Fluoren-9-yl)methyl 4-hydroxyazepane-1-carboxylate chemical structure, C21H23NO3, CAS 885954-52-9
(9H-Fluoren-9-yl)methyl 4-hydroxyazepane-1-carboxylate
CAS 885954-52-9C21H23NO3
9H-Fluoren-9-ylmethyl 4-aminoazepane-1-carboxylate chemical structure, C21H24N2O2, CAS 885954-48-3
9H-Fluoren-9-ylmethyl 4-aminoazepane-1-carboxylate
CAS 885954-48-3C21H24N2O2
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepane-2-carboxylic acid chemical structure, C22H23NO4, CAS 632350-45-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepane-2-carboxylic acid
CAS 632350-45-9C22H23NO4
(9H-Fluoren-9-yl)methyl 3-hydroxyazepane-1-carboxylate chemical structure, C21H23NO3, CAS 2764021-15-8
(9H-Fluoren-9-yl)methyl 3-hydroxyazepane-1-carboxylate
CAS 2764021-15-8C21H23NO3
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azepane-2-carboxylic acid chemical structure, C22H23NO4, CAS 2580103-36-0
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azepane-2-carboxylic acid
CAS 2580103-36-0C22H23NO4
(2S)-1-(9H-Fluoren-9-ylmethoxycarbonyl)azepane-2-carboxylic acid chemical structure, C22H23NO4, CAS 2322925-11-9
(2S)-1-(9H-Fluoren-9-ylmethoxycarbonyl)azepane-2-carboxylic acid
CAS 2322925-11-9C22H23NO4
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-methylazepane-1-carboxylate chemical structure, C22H25NO3, CAS 1701974-46-0
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-methylazepane-1-carboxylate
CAS 1701974-46-0C22H25NO3
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)azepane-1-carboxylate chemical structure, C22H25NO3, CAS 1600030-42-9
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)azepane-1-carboxylate
CAS 1600030-42-9C22H25NO3
1-[(9H-Fluoren-9-ylmethoxy)carbonyl]azepane-4-carboxylic acid chemical structure, C22H23NO4, CAS 1936476-88-8
1-[(9H-Fluoren-9-ylmethoxy)carbonyl]azepane-4-carboxylic acid
CAS 1936476-88-8C22H23NO4
(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)azepane-1-carboxylate chemical structure, C22H25NO3, CAS 1858660-56-6
(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)azepane-1-carboxylate
CAS 1858660-56-6C22H25NO3
(9H-Fluoren-9-yl)methyl 5-hydroxy-3,3-dimethylazepane-1-carboxylate chemical structure, C23H27NO3, CAS 1936207-02-1
(9H-Fluoren-9-yl)methyl 5-hydroxy-3,3-dimethylazepane-1-carboxylate
CAS 1936207-02-1C23H27NO3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepane-3-carboxylic acid chemical structure, C22H23NO4, CAS 2138526-02-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepane-3-carboxylic acid
CAS 2138526-02-8C22H23NO4
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azepan-4-yl)acetic acid chemical structure, C23H25NO4, CAS 2137618-41-6
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azepan-4-yl)acetic acid
CAS 2137618-41-6C23H25NO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,5-difluoroazepan-4-yl)acetic acid chemical structure, C23H23F2NO4, CAS 2260936-31-8
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,5-difluoroazepan-4-yl)acetic acid
CAS 2260936-31-8C23H23F2NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methylazepane-2-carboxylic acid chemical structure, C23H25NO4, CAS 610271-12-0
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methylazepane-2-carboxylic acid
CAS 610271-12-0C23H25NO4
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)(methyl)amino]acetic acid chemical structure, C24H28N2O4, CAS 2138014-35-2
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)(methyl)amino]acetic acid
CAS 2138014-35-2C24H28N2O4
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)amino]acetic acid chemical structure, C23H26N2O4, CAS 2172582-97-5
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)amino]acetic acid
CAS 2172582-97-5C23H26N2O4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-hydroxyazepan-4-yl)-2,2-difluoroacetic acid chemical structure, C23H23F2NO5, CAS 2243508-58-7
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-hydroxyazepan-4-yl)-2,2-difluoroacetic acid
CAS 2243508-58-7C23H23F2NO5
5-Amino-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azepane-4-carboxylic acid chemical structure, C22H24N2O4, CAS 2137549-83-6
5-Amino-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azepane-4-carboxylic acid
CAS 2137549-83-6C22H24N2O4
2-[N-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)acetamido]acetic acid chemical structure, C25H28N2O5, CAS 2137895-59-9
2-[N-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azepan-4-yl)acetamido]acetic acid
CAS 2137895-59-9C25H28N2O5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(prop-2-en-1-yl)azepane-4-carboxylic acid chemical structure, C25H27NO4, CAS 2383693-17-0
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(prop-2-en-1-yl)azepane-4-carboxylic acid
CAS 2383693-17-0C25H27NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxymethyl)azepane-4-carboxylic acid chemical structure, C24H27NO5, CAS 2384455-78-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxymethyl)azepane-4-carboxylic acid
CAS 2384455-78-9C24H27NO5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoroazepane-2-carboxylic acid chemical structure, C22H21F2NO4, CAS 2580183-25-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoroazepane-2-carboxylic acid
CAS 2580183-25-9C22H21F2NO4
(9H-Fluoren-9-yl)methyl 4-hydroxy-5-(hydroxymethyl)azepane-1-carboxylate chemical structure, C22H25NO4, CAS 2680885-05-4
(9H-Fluoren-9-yl)methyl 4-hydroxy-5-(hydroxymethyl)azepane-1-carboxylate
CAS 2680885-05-4C22H25NO4