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Murcko scaffold

Ring system with 4 rings and 24 atoms

25 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
25
With full pages
2
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

(9H-Fluoren-9-yl)methyl 6-hydroxy-1,4-oxazepane-4-carboxylate chemical structure, C20H21NO4, CAS 1934672-00-0
(9H-Fluoren-9-yl)methyl 6-hydroxy-1,4-oxazepane-4-carboxylate
CAS 1934672-00-0C20H21NO4
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-6-carboxylic acid chemical structure, C21H21NO5, CAS 1936071-00-9
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-6-carboxylic acid
CAS 1936071-00-9C21H21NO5
2-[4-(9H-Fluoren-9-ylmethoxycarbonyl)-1,4-oxazepan-6-yl]acetic acid chemical structure, C22H23NO5, CAS 2470438-91-4
2-[4-(9H-Fluoren-9-ylmethoxycarbonyl)-1,4-oxazepan-6-yl]acetic acid
CAS 2470438-91-4C22H23NO5
(2R)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-2-carboxylic acid chemical structure, C21H21NO5, CAS 2639622-06-1
(2R)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-2-carboxylic acid
CAS 2639622-06-1C21H21NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-1,4-oxazepane-6-carboxylic acid chemical structure, C23H25NO5, CAS 2803847-04-1
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-1,4-oxazepane-6-carboxylic acid
CAS 2803847-04-1C23H25NO5
(9H-Fluoren-9-yl)methyl 6-cyano-1,4-oxazepane-4-carboxylate chemical structure, C21H20N2O3, CAS 2803835-07-4
(9H-Fluoren-9-yl)methyl 6-cyano-1,4-oxazepane-4-carboxylate
CAS 2803835-07-4C21H20N2O3
1,4-Oxazepine-2,4(5H)-dicarboxylic acid, tetrahydro-, 4-(9H-fluoren-9-ylmethyl) ester chemical structure, C21H21NO5, CAS 2193060-93-2
1,4-Oxazepine-2,4(5H)-dicarboxylic acid, tetrahydro-, 4-(9H-fluoren-9-ylmethyl) ester
CAS 2193060-93-2C21H21NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-5-carboxylic acid chemical structure, C21H21NO5, CAS 2580178-75-0
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-5-carboxylic acid
CAS 2580178-75-0C21H21NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-dimethyl-1,4-oxazepane-3-carboxylic acid chemical structure, C23H25NO5, CAS 2639403-28-2
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-dimethyl-1,4-oxazepane-3-carboxylic acid
CAS 2639403-28-2C23H25NO5
(9H-Fluoren-9-yl)methyl 6-(hydroxymethyl)-6-methyl-1,4-oxazepane-4-carboxylate chemical structure, C22H25NO4, CAS 2764018-06-4
(9H-Fluoren-9-yl)methyl 6-(hydroxymethyl)-6-methyl-1,4-oxazepane-4-carboxylate
CAS 2764018-06-4C22H25NO4
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-(trifluoromethyl)-1,4-oxazepane-4-carboxylate chemical structure, C21H20F3NO4, CAS 2763946-46-7
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-(trifluoromethyl)-1,4-oxazepane-4-carboxylate
CAS 2763946-46-7C21H20F3NO4
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-methyl-1,4-oxazepane-4-carboxylate chemical structure, C21H23NO4, CAS 2764016-85-3
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-methyl-1,4-oxazepane-4-carboxylate
CAS 2764016-85-3C21H23NO4
(9H-Fluoren-9-yl)methyl 5-(hydroxymethyl)-1,4-oxazepane-4-carboxylate chemical structure, C21H23NO4, CAS 2763915-90-6
(9H-Fluoren-9-yl)methyl 5-(hydroxymethyl)-1,4-oxazepane-4-carboxylate
CAS 2763915-90-6C21H23NO4
(9H-Fluoren-9-yl)methyl 6-(hydroxymethyl)-1,4-oxazepane-4-carboxylate chemical structure, C21H23NO4, CAS 2764015-79-2
(9H-Fluoren-9-yl)methyl 6-(hydroxymethyl)-1,4-oxazepane-4-carboxylate
CAS 2764015-79-2C21H23NO4
(9H-Fluoren-9-yl)methyl 2-(2-hydroxyethyl)-1,4-oxazepane-4-carboxylate chemical structure, C22H25NO4, CAS 2763914-75-4
(9H-Fluoren-9-yl)methyl 2-(2-hydroxyethyl)-1,4-oxazepane-4-carboxylate
CAS 2763914-75-4C22H25NO4
(9H-Fluoren-9-yl)methyl 6-cyano-6-hydroxy-1,4-oxazepane-4-carboxylate chemical structure, C21H20N2O4, CAS 2770530-04-4
(9H-Fluoren-9-yl)methyl 6-cyano-6-hydroxy-1,4-oxazepane-4-carboxylate
CAS 2770530-04-4C21H20N2O4
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-7-carboxylic acid chemical structure, C21H21NO5, CAS 2751332-31-5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-7-carboxylic acid
CAS 2751332-31-5C21H21NO5
(3S)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-3-carboxylic acid chemical structure, C21H21NO5, CAS 2639623-14-4
(3S)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-3-carboxylic acid
CAS 2639623-14-4C21H21NO5
(S)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-6-carboxylic acid chemical structure, C21H21NO5, CAS 2381367-61-7
(S)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-6-carboxylic acid
CAS 2381367-61-7C21H21NO5
S-4-Fmoc-1,4-oxazepane-5-carboxylic acid chemical structure, C21H21NO5, CAS 2639624-12-5
S-4-Fmoc-1,4-oxazepane-5-carboxylic acid
CAS 2639624-12-5C21H21NO5
(R)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-6-carboxylic acid chemical structure, C21H21NO5, CAS 2742154-68-1
(R)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-6-carboxylic acid
CAS 2742154-68-1C21H21NO5
R-4-Fmoc-1,4-oxazepane-5-carboxylic acid chemical structure, C21H21NO5, CAS 2639622-05-0
R-4-Fmoc-1,4-oxazepane-5-carboxylic acid
CAS 2639622-05-0C21H21NO5
(2S)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-2-carboxylic acid chemical structure, C21H21NO5, CAS 2639623-69-9
(2S)-4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,4-oxazepane-2-carboxylic acid
CAS 2639623-69-9C21H21NO5
(R)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-3-carboxylic acid chemical structure, C21H21NO5, CAS 2639622-01-6
(R)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,4-oxazepane-3-carboxylic acid
CAS 2639622-01-6C21H21NO5