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Murcko scaffold

Ring system with 2 rings and 22 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
22
Chemicals
18
With full pages
1
Scaffold SMILES

O=C(CNC(=O)OCc1ccccc1)NCCc1cnc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)OCc1ccccc1)NCCc1cnc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3-(1H-Imidazol-5-yl)-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid chemical structure, C16H18N4O5, CAS 38972-84-8
3-(1H-Imidazol-5-yl)-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid
CAS 38972-84-8C16H18N4O5
Benzyl N-[2-[[1-hydrazinyl-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamate chemical structure, C16H20N6O4, CAS 17682-11-0
Benzyl N-[2-[[1-hydrazinyl-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamate
CAS 17682-11-0C16H20N6O4
Z-Gly-His-OH chemical structure, C16H18N4O5
Z-Gly-His-OH
C16H18N4O5
Z-Ala-his-OH chemical structure, C17H20N4O5, CAS 79458-92-7
Z-Ala-his-OH
CAS 79458-92-7C17H20N4O5
Z-Ala-his-ome chemical structure, C18H22N4O5, CAS 32303-82-5
Z-Ala-his-ome
CAS 32303-82-5C18H22N4O5
Z-Ile-his-OH chemical structure, C20H26N4O5, CAS 53935-11-8
Z-Ile-his-OH
CAS 53935-11-8C20H26N4O5
N-[(Benzyloxy)carbonyl]-L-leucyl-L-histidine chemical structure, C20H26N4O5, CAS 79778-48-6
N-[(Benzyloxy)carbonyl]-L-leucyl-L-histidine
CAS 79778-48-6C20H26N4O5
Methyl 3-(1H-imidazol-5-yl)-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate chemical structure, C18H22N4O5
Methyl 3-(1H-imidazol-5-yl)-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate
C18H22N4O5
Z-Gly-his-nhnh2 chemical structure, C16H20N6O4
Z-Gly-his-nhnh2
C16H20N6O4
N-[(Phenylmethoxy)carbonyl]-L-I+/--glutamyl-L-histidine 1-(1,1-dimethylethyl) 2-methyl ester chemical structure, C24H32N4O7, CAS 3967-22-4
N-[(Phenylmethoxy)carbonyl]-L-I+/--glutamyl-L-histidine 1-(1,1-dimethylethyl) 2-methyl ester
CAS 3967-22-4C24H32N4O7
N-[(Benzyloxy)carbonyl]glycyl-L-histidyl-L-lysinamide chemical structure, C22H31N7O5, CAS 191107-95-6
N-[(Benzyloxy)carbonyl]glycyl-L-histidyl-L-lysinamide
CAS 191107-95-6C22H31N7O5
N-[(Benzyloxy)carbonyl]-L-leucyl-D-histidine chemical structure, C20H26N4O5, CAS 79778-49-7
N-[(Benzyloxy)carbonyl]-L-leucyl-D-histidine
CAS 79778-49-7C20H26N4O5
3-(1H-Imidazol-5-yl)-2-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]propanoic acid chemical structure, C20H26N4O5
3-(1H-Imidazol-5-yl)-2-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]propanoic acid
C20H26N4O5
(S)-Benzyl (2-((1-hydrazinyl-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)carbamate chemical structure, C16H20N6O4
(S)-Benzyl (2-((1-hydrazinyl-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)carbamate
C16H20N6O4
(2R)-3-(1H-Imidazol-5-yl)-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid chemical structure, C16H18N4O5
(2R)-3-(1H-Imidazol-5-yl)-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid
C16H18N4O5
Methyl (2R)-3-(1H-imidazol-5-yl)-2-[[(2R)-2-(phenylmethoxycarbonylamino)propanoyl]amino]propanoate chemical structure, C18H22N4O5
Methyl (2R)-3-(1H-imidazol-5-yl)-2-[[(2R)-2-(phenylmethoxycarbonylamino)propanoyl]amino]propanoate
C18H22N4O5
Cbz-D-xiIle-D-His-OH chemical structure, C20H26N4O5
Cbz-D-xiIle-D-His-OH
C20H26N4O5
N-[(Benzyloxy)carbonyl]glycylhistidinamide chemical structure, C16H19N5O4, CAS 10467-32-0
N-[(Benzyloxy)carbonyl]glycylhistidinamide
CAS 10467-32-0C16H19N5O4