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Murcko scaffold

4-(Furan-2-yl)pyrimidine scaffold

174 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
174
With full pages
4
Scaffold SMILES

c1coc(-c2ccncn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Furan-2-yl)pyrimidine page
Murcko scaffold c1coc(-c2ccncn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 174 chemicals

2,4-Diamino-6-(5-nitrofuryl-2)-5-ethylpyrimidine chemical structure, C10H11N5O3, CAS 57119-09-2
2,4-Diamino-6-(5-nitrofuryl-2)-5-ethylpyrimidine
CAS 57119-09-2C10H11N5O3
4-Chloro-6-(2-furyl)-2-methylsulfanylpyrimidine-5-carbonitrile chemical structure, C10H6ClN3OS, CAS 137447-07-5
4-Chloro-6-(2-furyl)-2-methylsulfanylpyrimidine-5-carbonitrile
CAS 137447-07-5C10H6ClN3OS
4-(Furan-2-yl)pyrimidine chemical structure, C8H6N2O, CAS 17749-82-5
4-(Furan-2-yl)pyrimidine
CAS 17749-82-5C8H6N2O
2-((4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid chemical structure, C11H7F3N2O3S, CAS 505064-81-3
2-((4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid
CAS 505064-81-3C11H7F3N2O3S
Ethyl 2-[4-(2-furyl)-6-(trifluoromethyl)pyrimidin-2-ylthio]acetate chemical structure, C13H11F3N2O3S, CAS 505064-82-4
Ethyl 2-[4-(2-furyl)-6-(trifluoromethyl)pyrimidin-2-ylthio]acetate
CAS 505064-82-4C13H11F3N2O3S
Methyl 2-[4-(furan-2-yl)pyrimidin-2-yl]sulfanylacetate chemical structure, C11H10N2O3S, CAS 692287-28-8
Methyl 2-[4-(furan-2-yl)pyrimidin-2-yl]sulfanylacetate
CAS 692287-28-8C11H10N2O3S
2-[4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl-N-(2-methoxyethyl)acetamide chemical structure, C14H14F3N3O3S, CAS 505058-44-6
2-[4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl-N-(2-methoxyethyl)acetamide
CAS 505058-44-6C14H14F3N3O3S
4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine chemical structure, C9H6F3N3O, CAS 580-50-7
4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine
CAS 580-50-7C9H6F3N3O
N-tert-Butyl-4-{[4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}butanamide chemical structure, C17H20F3N3O2S, CAS 5161-52-4
N-tert-Butyl-4-{[4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}butanamide
CAS 5161-52-4C17H20F3N3O2S
4-(2-Furanyl)-6-methoxy-2-pyrimidinamine chemical structure, C9H9N3O2, CAS 675819-65-5
4-(2-Furanyl)-6-methoxy-2-pyrimidinamine
CAS 675819-65-5C9H9N3O2
4-(2-Furyl)pyrimidin-2-amine chemical structure, C8H7N3O, CAS 206564-00-3
4-(2-Furyl)pyrimidin-2-amine
CAS 206564-00-3C8H7N3O
4-Ethoxy-6-(furan-2-yl)pyrimidin-2-amine chemical structure, C10H11N3O2, CAS 675819-61-1
4-Ethoxy-6-(furan-2-yl)pyrimidin-2-amine
CAS 675819-61-1C10H11N3O2
4-(2-Furanyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine chemical structure, C9H7F3N4O, CAS 832737-70-9
4-(2-Furanyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine
CAS 832737-70-9C9H7F3N4O
2-{[4-(2-Furyl)-2-pyrimidinyl]sulfanyl}acetonitrile chemical structure, C10H7N3OS, CAS 692287-29-9
2-{[4-(2-Furyl)-2-pyrimidinyl]sulfanyl}acetonitrile
CAS 692287-29-9C10H7N3OS
3-((4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanoyl chloride chemical structure, C12H8ClF3N2O2S, CAS 862704-70-9
3-((4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanoyl chloride
CAS 862704-70-9C12H8ClF3N2O2S
4-(Difluoromethyl)-6-(2-furyl)-2-hydrazinopyrimidine chemical structure, C9H8F2N4O, CAS 869946-84-9
4-(Difluoromethyl)-6-(2-furyl)-2-hydrazinopyrimidine
CAS 869946-84-9C9H8F2N4O
2-Chloro-4-(furan-2-yl)pyrimidine chemical structure, C8H5ClN2O, CAS 124959-28-0
2-Chloro-4-(furan-2-yl)pyrimidine
CAS 124959-28-0C8H5ClN2O
2-Chloro-N-[4-(furan-2-yl)pyrimidin-2-yl]acetamide chemical structure, C10H8ClN3O2, CAS 832740-97-3
2-Chloro-N-[4-(furan-2-yl)pyrimidin-2-yl]acetamide
CAS 832740-97-3C10H8ClN3O2
4-Chloro-6-(2-furyl)-5-methylpyrimidine-2-amine chemical structure, C9H8ClN3O, CAS 28565-40-4
4-Chloro-6-(2-furyl)-5-methylpyrimidine-2-amine
CAS 28565-40-4C9H8ClN3O
5-Bromo-4-(2-furyl)-2-pyrimidinylamine chemical structure, C8H6BrN3O, CAS 357285-97-3
5-Bromo-4-(2-furyl)-2-pyrimidinylamine
CAS 357285-97-3C8H6BrN3O
2-Amino-4-(furan-2-yl)pyrimidine-5-carbonitrile chemical structure, C9H6N4O, CAS 357284-81-2
2-Amino-4-(furan-2-yl)pyrimidine-5-carbonitrile
CAS 357284-81-2C9H6N4O
2-Amino-4-(furan-2-yl)-6-(methylsulfinyl)pyrimidine-5-carbonitrile chemical structure, C10H8N4O2S, CAS 357286-73-8
2-Amino-4-(furan-2-yl)-6-(methylsulfinyl)pyrimidine-5-carbonitrile
CAS 357286-73-8C10H8N4O2S
Ethyl 2-((4-(furan-2-yl)pyrimidin-2-yl)thio)acetate chemical structure, C12H12N2O3S, CAS 937599-96-7
Ethyl 2-((4-(furan-2-yl)pyrimidin-2-yl)thio)acetate
CAS 937599-96-7C12H12N2O3S
2-{[4-(Furan-2-yl)pyrimidin-2-yl]sulfanyl}-N-(prop-2-en-1-yl)acetamide chemical structure, C13H13N3O2S, CAS 828276-25-1
2-{[4-(Furan-2-yl)pyrimidin-2-yl]sulfanyl}-N-(prop-2-en-1-yl)acetamide
CAS 828276-25-1C13H13N3O2S