Murcko scaffold
2-Oxabicyclo[2.2.1]heptane scaffold
249 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 7
- Chemicals
- 249
- With full pages
- 51
Scaffold SMILES
C1CC2CC1CO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 249 chemicals
RefChem:192788
CAS 56985-32-1C21H34O4
9,11-Methanoepoxy PGH2
CAS 56985-40-1C21H34O4
15-Hydroxy-11alpha,9alpha-(epoxymethano)prosta-5,13-dienoic acid
CAS 76898-47-0C21H34O4
11,9-Epoxymethanoprostaglandin H1
CAS 72517-81-8C21H36O4
![2-Oxabicyclo[2.2.1]heptan-6-ol chemical structure, C6H10O2, CAS 1823300-24-8](/s/YFOLSJPLSOPDLT-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptan-6-ol
CAS 1823300-24-8C6H10O2
rac-(1R,4R,6R)-2-Oxabicyclo(2.2.1)heptan-6-ol
CAS 36368-46-4C6H10O2
![2-Oxabicyclo[2.2.1]heptane chemical structure, C6H10O, CAS 279-25-4](/s/JLVDVIXDYDGVLS-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptane
CAS 279-25-4C6H10O
![2-Oxabicyclo[2.2.1]heptan-5-ol chemical structure, C6H10O2, CAS 1823661-22-8](/s/HNOQJUJGVQARBI-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptan-5-ol
CAS 1823661-22-8C6H10O2
Cyclocerberidol
CAS 126594-66-9C9H16O4
![[(1S,4S,5S,7R)-5-Amino-2-oxabicyclo[2.2.1]heptan-7-yl]methanol chemical structure, C7H13NO2, CAS 125249-66-3](/s/MQZTWTHEBBWSSG-UHFFFAOYSA-N.svg)
[(1S,4S,5S,7R)-5-Amino-2-oxabicyclo[2.2.1]heptan-7-yl]methanol
CAS 125249-66-3C7H13NO2
![3-Methoxy-1,4-dimethyl-2-oxabicyclo[2.2.1]heptan-7-ol chemical structure, C9H16O3, CAS 140220-61-7](/s/JNRWZASQDZPGHE-UHFFFAOYSA-N.svg)
3-Methoxy-1,4-dimethyl-2-oxabicyclo[2.2.1]heptan-7-ol
CAS 140220-61-7C9H16O3
![2-Oxabicyclo[2.2.1]heptan-4-ylmethanol chemical structure, C7H12O2, CAS 132667-30-2](/s/WIQFMCFXISMDSL-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptan-4-ylmethanol
CAS 132667-30-2C7H12O2
![4-Methyl-1-propan-2-yl-2-oxabicyclo[2.2.1]heptane chemical structure, C10H18O, CAS 152562-89-5](/s/GUNQMDRPDFBMSV-UHFFFAOYSA-N.svg)
4-Methyl-1-propan-2-yl-2-oxabicyclo[2.2.1]heptane
CAS 152562-89-5C10H18O
![(1R,4S,7R)-1,3,3,7-Tetramethyl-2-oxabicyclo[2.2.1]heptane chemical structure, C10H18O, CAS 15404-56-5](/s/PNNPDYWCSNYYBG-KHQFGBGNSA-N.svg)
(1R,4S,7R)-1,3,3,7-Tetramethyl-2-oxabicyclo[2.2.1]heptane
CAS 15404-56-5C10H18O
2-Oxabicyclo(2.2.1)heptane-3-carboxylic acid
CAS 2168525-36-6C7H10O3
5-Trans U-46619
CAS 330796-58-2C21H34O4
![(1S)-4,7,7-Trimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride chemical structure, C10H15ClO2, CAS 79634-76-7](/s/HPUSKHGKZGYUPJ-QVDQXJPCSA-N.svg)
(1S)-4,7,7-Trimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride
CAS 79634-76-7C10H15ClO2
Delta17-U-46619
CAS 946602-01-3C21H32O4
![2-Oxabicyclo[2.2.1]heptan-6-amine chemical structure, C6H11NO, CAS 1891076-47-3](/s/WHCQIGAGLHHFPZ-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptan-6-amine
CAS 1891076-47-3C6H11NO
![2-Oxabicyclo[2.2.1]heptane-4-carbonitrile, 6-hydroxy- chemical structure, C7H9NO2, CAS 2114200-66-5](/s/ONVBKKKHXRWJPL-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptane-4-carbonitrile, 6-hydroxy-
CAS 2114200-66-5C7H9NO2
![1,4,7,7-Tetramethyl-2-oxabicyclo[2.2.1]heptane chemical structure, C10H18O, CAS 67310-38-7](/s/KUTUDDVNXLFTRY-UHFFFAOYSA-N.svg)
1,4,7,7-Tetramethyl-2-oxabicyclo[2.2.1]heptane
CAS 67310-38-7C10H18O
![2-Oxabicyclo[2.2.1]heptan-5-amine chemical structure, C6H11NO, CAS 1453906-19-8](/s/PXHCGNSPYJSHAX-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.1]heptan-5-amine
CAS 1453906-19-8C6H11NO
2-Oxabicyclo(2.2.1)heptane-1-carboxylic acid
CAS 2243509-26-2C7H10O3
5-Trans U-44069
CAS 330796-57-1C21H34O4
- 2-Oxabicyclo[2.2.1]heptane-6-carboxylic acid1896924-33-6C7H10O3
- {2-Oxabicyclo[2.2.1]heptan-6-yl}methanol1895191-63-5C7H12O2
- 2-Oxabicyclo[2.2.1]heptane-6-carbaldehyde1895262-51-7C7H10O2
- 1-{2-Oxabicyclo[2.2.1]heptan-6-yl}methanamine1895030-45-1C7H13NO
- 2-{2-Oxabicyclo[2.2.1]heptan-6-yl}acetic acid1895262-62-0C8H12O3
- 2-(2-Oxabicyclo[2.2.1]heptan-6-yl)ethanol1895440-02-4C8H14O2
- 2-Oxabicyclo[2.2.1]heptane-6-carbonitrile1895030-48-4C7H9NO
- 6-Hydroxy-2-oxabicyclo[2.2.1]heptane-4-carboxylic acid1891207-07-0C7H10O4
- Methyl 6-hydroxy-2-oxabicyclo[2.2.1]heptane-4-carboxylate1896751-08-8C8H12O4
- Methyl 6-amino-2-oxabicyclo[2.2.1]heptane-4-carboxylate1897014-02-6C8H13NO3
- 2-Oxabicyclo[2.2.1]heptan-4-amine2253631-33-1C6H11NO
- 4-(Hydroxymethyl)-2-oxabicyclo[2.2.1]heptan-6-ol1823710-63-9C7H12O3
- (1S,4R)-1,4-Dimethyl-2-oxabicyclo[2.2.1]heptan-3-ol1933746-17-8C8H14O2
- 1-Methyl-2-oxabicyclo[2.2.1]heptane-4-carboxylic acid2243513-71-3C8H12O3
- Methyl1-(aminomethyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylatehydrochloride2260937-37-7C9H16ClNO3
- Methyl 1-(aminomethyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylate2260936-10-3C9H15NO3
- 2-Oxabicyclo[2.2.1]heptan-4-amine hydrochloride2253632-53-8C6H12ClNO
- (4-Methyl-2-oxabicyclo(2.2.1)heptan-1-yl)methanamine hydrochloride2248349-36-0C8H16ClNO
- 1-{4-Methyl-2-oxabicyclo[2.2.1]heptan-1-yl}methanamine2248349-35-9C8H15NO
- 2-Oxabicyclo(2.2.1)heptane-4-carboxylic acid2168378-43-4C7H10O3
- (4-Methyl-2-oxabicyclo(2.2.1)heptan-1-yl)methanesulfonyl chloride2248324-39-0C8H13ClO3S
- tert-Butyl 1-(aminomethyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylate2287283-79-6C12H21NO3
- 1-({[(tert-Butoxy)carbonyl]amino}methyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylic acid2260936-11-4C13H21NO5
- Methyl 1-(chlorosulfonylmethyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylate2260931-53-9C9H13ClO5S
Related scaffolds
Same ring framework with different atoms or bond orders
