CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
20
With full pages
3
Scaffold SMILES

c1ccc(CCNc2ncnc3[nH]ncc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCNc2ncnc3[nH]ncc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

6-Chloro-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C13H12ClN5, CAS 6958-84-5
6-Chloro-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 6958-84-5C13H12ClN5
6-Chloro-1-methyl-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C14H14ClN5, CAS 6958-86-7
6-Chloro-1-methyl-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 6958-86-7C14H14ClN5
1-Methyl-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C14H15N5, CAS 102353-77-5
1-Methyl-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 102353-77-5C14H15N5
N-[2-(2,4-Dichlorophenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C13H11Cl2N5, CAS 732270-05-2
N-[2-(2,4-Dichlorophenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 732270-05-2C13H11Cl2N5
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C15H17N5O2, CAS 732270-08-5
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 732270-08-5C15H17N5O2
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H19N5O2, CAS 869072-63-9
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 869072-63-9C16H19N5O2
4-(2-Phenethylamino)-1H-pyrazolo((3,4d))pyrimidine hydrochloride chemical structure, C13H14ClN5, CAS 42204-29-5
4-(2-Phenethylamino)-1H-pyrazolo((3,4d))pyrimidine hydrochloride
CAS 42204-29-5C13H14ClN5
N-[2-(4-Methoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C14H15N5O, CAS 1021023-72-2
N-[2-(4-Methoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 1021023-72-2C14H15N5O
4-(2-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide chemical structure, C13H14N6O2S, CAS 1021208-21-8
4-(2-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide
CAS 1021208-21-8C13H14N6O2S
4-(2-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)phenol chemical structure, C13H13N5O, CAS 1021023-73-3
4-(2-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)phenol
CAS 1021023-73-3C13H13N5O
N-(2-(4-(Phenethylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)propane-1-sulfonamide chemical structure, C18H24N6O2S, CAS 1172830-23-7
N-(2-(4-(Phenethylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)propane-1-sulfonamide
CAS 1172830-23-7C18H24N6O2S
N-[2-(3-Methoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C15H17N5O, CAS 1912575-18-8
N-[2-(3-Methoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 1912575-18-8C15H17N5O
1,1,1-Trifluoro-3-({1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}amino)-2-phenylpropan-2-ol chemical structure, C15H14F3N5O, CAS 2380079-19-4
1,1,1-Trifluoro-3-({1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}amino)-2-phenylpropan-2-ol
CAS 2380079-19-4C15H14F3N5O
2-({1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}amino)-1-[4-(methylsulfanyl)phenyl]ethan-1-ol chemical structure, C15H17N5OS, CAS 2380088-76-4
2-({1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}amino)-1-[4-(methylsulfanyl)phenyl]ethan-1-ol
CAS 2380088-76-4C15H17N5OS
N-[2-Methoxy-2-(2-methylphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H19N5O, CAS 2380166-85-6
N-[2-Methoxy-2-(2-methylphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2380166-85-6C16H19N5O
N-[2-(2-Fluorophenyl)-2-methoxypropyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H18FN5O, CAS 2380083-74-7
N-[2-(2-Fluorophenyl)-2-methoxypropyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2380083-74-7C16H18FN5O
N-[2-Methoxy-2-(3-methoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H19N5O2, CAS 2380082-10-8
N-[2-Methoxy-2-(3-methoxyphenyl)ethyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2380082-10-8C16H19N5O2
N-[2-(3-Chlorophenyl)-2-methoxypropyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H18ClN5O, CAS 2380078-04-4
N-[2-(3-Chlorophenyl)-2-methoxypropyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2380078-04-4C16H18ClN5O
N-(2-Methoxy-2-phenylbutyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C17H21N5O, CAS 2380079-36-5
N-(2-Methoxy-2-phenylbutyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2380079-36-5C17H21N5O
N-[2-(4-Methoxyphenyl)ethyl]-N-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C15H17N5O, CAS 2741957-42-4
N-[2-(4-Methoxyphenyl)ethyl]-N-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 2741957-42-4C15H17N5O