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Murcko scaffold

Diphenylacetylene scaffold

795 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
795
With full pages
36
Scaffold SMILES

C(#Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Diphenylacetylene page
Murcko scaffold C(#Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 795 chemicals

Diphenylacetylene chemical structure, C14H10, CAS 501-65-5
Diphenylacetylene
CAS 501-65-5C14H10
1-Chloro-2-(phenylethynyl)benzene chemical structure, C14H9Cl, CAS 10271-57-5
1-Chloro-2-(phenylethynyl)benzene
CAS 10271-57-5C14H9Cl
Bis[p-chlorophenyl]acetylene chemical structure, C14H8Cl2, CAS 1820-42-4
Bis[p-chlorophenyl]acetylene
CAS 1820-42-4C14H8Cl2
1-((1,1-Dimethylethyl)amino)-3-(2-((4-(methylthio)phenyl)ethynyl)phenoxy)-2-propanol hydrochloride chemical structure, C22H27NO2S, CAS 126661-21-0
1-((1,1-Dimethylethyl)amino)-3-(2-((4-(methylthio)phenyl)ethynyl)phenoxy)-2-propanol hydrochloride
CAS 126661-21-0C22H27NO2S
1-(2-((3-(Dimethylamino)phenyl)ethynyl)phenoxy)-3-((1,1-dimethylethyl)amino)-2-propanol chemical structure, C23H30N2O2, CAS 126661-22-1
1-(2-((3-(Dimethylamino)phenyl)ethynyl)phenoxy)-3-((1,1-dimethylethyl)amino)-2-propanol
CAS 126661-22-1C23H30N2O2
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-(2-((4-(1-methylethyl)phenyl)ethynyl)phenoxy)- chemical structure, C24H31NO2, CAS 126661-25-4
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-(2-((4-(1-methylethyl)phenyl)ethynyl)phenoxy)-
CAS 126661-25-4C24H31NO2
1-(tert-Butylamino)-3-(2-((4-(dimethylamino)phenyl)ethynyl)-5-fluorophenoxy)propan-2-ol chemical structure, C23H29FN2O2, CAS 126661-27-6
1-(tert-Butylamino)-3-(2-((4-(dimethylamino)phenyl)ethynyl)-5-fluorophenoxy)propan-2-ol
CAS 126661-27-6C23H29FN2O2
2-Propanol, 1-(2-((3-((dimethylamino)methyl)phenyl)ethynyl)phenoxy)-3-((1,1-dimethylethyl)amino)- chemical structure, C24H32N2O2, CAS 126661-35-6
2-Propanol, 1-(2-((3-((dimethylamino)methyl)phenyl)ethynyl)phenoxy)-3-((1,1-dimethylethyl)amino)-
CAS 126661-35-6C24H32N2O2
1-(tert-Butylamino)-3-[2-(phenylethynyl)phenoxy]propan-2-ol chemical structure, C21H25NO2, CAS 102770-58-1
1-(tert-Butylamino)-3-[2-(phenylethynyl)phenoxy]propan-2-ol
CAS 102770-58-1C21H25NO2
1-(tert-Butylamino)-3-(2-{[4-(dimethylamino)phenyl]ethynyl}phenoxy)propan-2-ol chemical structure, C23H30N2O2, CAS 102770-89-8
1-(tert-Butylamino)-3-(2-{[4-(dimethylamino)phenyl]ethynyl}phenoxy)propan-2-ol
CAS 102770-89-8C23H30N2O2
Benzene, 1,1'-(1,2-ethynediyl)bis(2-nitro- chemical structure, C14H8N2O4, CAS 25407-11-8
Benzene, 1,1'-(1,2-ethynediyl)bis(2-nitro-
CAS 25407-11-8C14H8N2O4
N,N-Bis(2-chloroethyl)-4-[2-(4-nitrophenyl)ethynyl]aniline chemical structure, C18H16Cl2N2O2, CAS 2735-16-2
N,N-Bis(2-chloroethyl)-4-[2-(4-nitrophenyl)ethynyl]aniline
CAS 2735-16-2C18H16Cl2N2O2
N-[2-[2-(3-Methoxyphenyl)ethynyl]phenyl]acetamide chemical structure, C17H15NO2, CAS 26385-34-2
N-[2-[2-(3-Methoxyphenyl)ethynyl]phenyl]acetamide
CAS 26385-34-2C17H15NO2
1-Bromo-4-(phenylethynyl)benzene chemical structure, C14H9Br, CAS 13667-12-4
1-Bromo-4-(phenylethynyl)benzene
CAS 13667-12-4C14H9Br
3-Phenylethynyl-benzoic acid chemical structure, C15H10O2, CAS 93866-50-3
3-Phenylethynyl-benzoic acid
CAS 93866-50-3C15H10O2
1-Bromo-2-[2-(2-bromophenyl)ethynyl]benzene chemical structure, C14H8Br2, CAS 38399-13-2
1-Bromo-2-[2-(2-bromophenyl)ethynyl]benzene
CAS 38399-13-2C14H8Br2
[2-(2-Phenylethynyl)phenyl]boronic acid chemical structure, C14H11BO2, CAS 124160-41-4
[2-(2-Phenylethynyl)phenyl]boronic acid
CAS 124160-41-4C14H11BO2
Methyl 2-[2-(2-methoxycarbonylphenyl)ethynyl]benzoate chemical structure, C18H14O4, CAS 970-93-4
Methyl 2-[2-(2-methoxycarbonylphenyl)ethynyl]benzoate
CAS 970-93-4C18H14O4
1-Chloro-2-[2-(4-chlorophenyl)ethynyl]benzene chemical structure, C14H8Cl2, CAS 7504-28-1
1-Chloro-2-[2-(4-chlorophenyl)ethynyl]benzene
CAS 7504-28-1C14H8Cl2
1-Chloro-4-(phenylethynyl)benzene chemical structure, C14H9Cl, CAS 5172-02-1
1-Chloro-4-(phenylethynyl)benzene
CAS 5172-02-1C14H9Cl
di-p-Tolylacetylene chemical structure, C16H14, CAS 2789-88-0
di-p-Tolylacetylene
CAS 2789-88-0C16H14
1-Methyl-4-((4-propylphenyl)ethynyl)benzene chemical structure, C18H18, CAS 184161-94-2
1-Methyl-4-((4-propylphenyl)ethynyl)benzene
CAS 184161-94-2C18H18
4-(Phenylethynyl)benzaldehyde chemical structure, C15H10O, CAS 57341-98-7
4-(Phenylethynyl)benzaldehyde
CAS 57341-98-7C15H10O
1-Ethoxy-4-((4-pentylphenyl)ethynyl)benzene chemical structure, C21H24O, CAS 95480-29-8
1-Ethoxy-4-((4-pentylphenyl)ethynyl)benzene
CAS 95480-29-8C21H24O