CompoundList
Sign in
Murcko scaffold

1-Benzyl-1,4-diazepane scaffold

197 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
197
With full pages
28
Scaffold SMILES

c1ccc(CN2CCCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-1,4-diazepane page
Murcko scaffold c1ccc(CN2CCCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 197 chemicals

Ethyl (4-methyl-1,4-diazepan-1-yl)(4-methylphenyl)acetate chemical structure, C17H26N2O2, CAS 7550-11-0
Ethyl (4-methyl-1,4-diazepan-1-yl)(4-methylphenyl)acetate
CAS 7550-11-0C17H26N2O2
1-Benzyl-1,4-diazepane chemical structure, C12H18N2, CAS 4410-12-2
1-Benzyl-1,4-diazepane
CAS 4410-12-2C12H18N2
4-Benzyl-1,4-diazepan-1-amine chemical structure, C12H19N3, CAS 6955-28-8
4-Benzyl-1,4-diazepan-1-amine
CAS 6955-28-8C12H19N3
1-[(3-Methoxyphenyl)methyl]-1,4-diazepane chemical structure, C13H20N2O, CAS 502142-36-1
1-[(3-Methoxyphenyl)methyl]-1,4-diazepane
CAS 502142-36-1C13H20N2O
1-((4-Methoxyphenyl)methyl)-1,4-diazepane chemical structure, C13H20N2O, CAS 61903-26-2
1-((4-Methoxyphenyl)methyl)-1,4-diazepane
CAS 61903-26-2C13H20N2O
3-(1,4-Diazepan-1-ylmethyl)benzonitrile chemical structure, C13H17N3, CAS 500878-94-4
3-(1,4-Diazepan-1-ylmethyl)benzonitrile
CAS 500878-94-4C13H17N3
1-(2,3-Dichlorobenzyl)-4-methyl-1,4-diazepane chemical structure, C13H18Cl2N2, CAS 414879-17-7
1-(2,3-Dichlorobenzyl)-4-methyl-1,4-diazepane
CAS 414879-17-7C13H18Cl2N2
2-Bromo-6-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenol chemical structure, C14H21BrN2O2, CAS 331854-54-7
2-Bromo-6-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenol
CAS 331854-54-7C14H21BrN2O2
1-[(4-Bromophenyl)methyl]-4-methyl-1,4-diazepane chemical structure, C13H19BrN2, CAS 280560-78-3
1-[(4-Bromophenyl)methyl]-4-methyl-1,4-diazepane
CAS 280560-78-3C13H19BrN2
1-[(4-Fluorophenyl)methyl]-4-methyl-1,4-diazepane chemical structure, C13H19FN2, CAS 280560-98-7
1-[(4-Fluorophenyl)methyl]-4-methyl-1,4-diazepane
CAS 280560-98-7C13H19FN2
1-Methyl-4-(3-nitrobenzyl)-1,4-diazepane chemical structure, C13H19N3O2, CAS 280560-81-8
1-Methyl-4-(3-nitrobenzyl)-1,4-diazepane
CAS 280560-81-8C13H19N3O2
1-Methyl-4-[4-(trifluoromethyl)benzyl]-1,4-diazepane chemical structure, C14H19F3N2, CAS 280560-85-2
1-Methyl-4-[4-(trifluoromethyl)benzyl]-1,4-diazepane
CAS 280560-85-2C14H19F3N2
1-(3-Fluorobenzyl)-4-methyl-1,4-diazepane chemical structure, C13H19FN2, CAS 414881-16-6
1-(3-Fluorobenzyl)-4-methyl-1,4-diazepane
CAS 414881-16-6C13H19FN2
1-[(3-Bromophenyl)methyl]-4-methyl-1,4-diazepane chemical structure, C13H19BrN2, CAS 414885-80-6
1-[(3-Bromophenyl)methyl]-4-methyl-1,4-diazepane
CAS 414885-80-6C13H19BrN2
1-[(4-Methoxy-2,3-dimethylphenyl)methyl]-4-methyl-1,4-diazepane chemical structure, C16H26N2O, CAS 5266-55-7
1-[(4-Methoxy-2,3-dimethylphenyl)methyl]-4-methyl-1,4-diazepane
CAS 5266-55-7C16H26N2O
1-(1-Phenylethyl)-1,4-diazepane chemical structure, C13H20N2, CAS 685892-10-8
1-(1-Phenylethyl)-1,4-diazepane
CAS 685892-10-8C13H20N2
4-(4-Benzyl-1,4-diazepan-1-yl)-4-oxobutanoic acid chemical structure, C16H22N2O3, CAS 396105-43-4
4-(4-Benzyl-1,4-diazepan-1-yl)-4-oxobutanoic acid
CAS 396105-43-4C16H22N2O3
1-(2-Chloro-6-fluorobenzyl)-1,4-diazepane chemical structure, C12H16ClFN2, CAS 244022-69-3
1-(2-Chloro-6-fluorobenzyl)-1,4-diazepane
CAS 244022-69-3C12H16ClFN2
2-[4-(2,4-Dichlorobenzyl)-1,4-diazepan-1-yl]ethan-1-ol chemical structure, C14H20Cl2N2O, CAS 646455-64-3
2-[4-(2,4-Dichlorobenzyl)-1,4-diazepan-1-yl]ethan-1-ol
CAS 646455-64-3C14H20Cl2N2O
1-(2-Chlorobenzyl)-1,4-diazepane chemical structure, C12H17ClN2, CAS 76141-88-3
1-(2-Chlorobenzyl)-1,4-diazepane
CAS 76141-88-3C12H17ClN2
Ethyl 4-[(2,4-dichlorophenyl)methyl]-1,4-diazepane-1-carboxylate chemical structure, C15H20Cl2N2O2, CAS 646455-84-7
Ethyl 4-[(2,4-dichlorophenyl)methyl]-1,4-diazepane-1-carboxylate
CAS 646455-84-7C15H20Cl2N2O2
1-(4-Fluorobenzyl)-1,4-diazepane chemical structure, C12H17FN2, CAS 76141-89-4
1-(4-Fluorobenzyl)-1,4-diazepane
CAS 76141-89-4C12H17FN2
1-(4-Bromo-2-fluorobenzyl)homopiperazine chemical structure, C12H16BrFN2, CAS 646455-62-1
1-(4-Bromo-2-fluorobenzyl)homopiperazine
CAS 646455-62-1C12H16BrFN2
1-((2-Chloro-6-fluorophenyl)methyl)-1,4-diazepane dihydrochloride chemical structure, C12H18Cl3FN2, CAS 1049733-74-5
1-((2-Chloro-6-fluorophenyl)methyl)-1,4-diazepane dihydrochloride
CAS 1049733-74-5C12H18Cl3FN2