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Murcko scaffold

Ring system with 3 rings and 21 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
4
With full pages
4
Scaffold SMILES

O=C1CC(C(=O)Nc2cccs2)N(Cc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(C(=O)Nc2cccs2)N(Cc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Methyl 2-{[(2-benzyl-5-oxo-3-pyrazolidinyl)carbonyl]amino}-4,5-dimethyl-3-thiophenecarboxylate chemical structure, C19H21N3O4S, CAS 956742-18-0
Methyl 2-{[(2-benzyl-5-oxo-3-pyrazolidinyl)carbonyl]amino}-4,5-dimethyl-3-thiophenecarboxylate
CAS 956742-18-0C19H21N3O4S
Ethyl 2-[(2-benzyl-5-oxopyrazolidine-3-carbonyl)amino]-5-ethylthiophene-3-carboxylate chemical structure, C20H23N3O4S, CAS 956785-51-6
Ethyl 2-[(2-benzyl-5-oxopyrazolidine-3-carbonyl)amino]-5-ethylthiophene-3-carboxylate
CAS 956785-51-6C20H23N3O4S
Methyl 2-[(2-benzyl-5-oxopyrazolidine-3-carbonyl)amino]-5-ethylthiophene-3-carboxylate chemical structure, C19H21N3O4S, CAS 956791-00-7
Methyl 2-[(2-benzyl-5-oxopyrazolidine-3-carbonyl)amino]-5-ethylthiophene-3-carboxylate
CAS 956791-00-7C19H21N3O4S
Methyl 2-{[(2-benzyl-5-oxopyrazolidin-3-yl)carbonyl]amino}-5-methylthiophene-3-carboxylate chemical structure, C18H19N3O4S, CAS 956573-61-8
Methyl 2-{[(2-benzyl-5-oxopyrazolidin-3-yl)carbonyl]amino}-5-methylthiophene-3-carboxylate
CAS 956573-61-8C18H19N3O4S