Murcko scaffold
Ring system with 4 rings and 28 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 28
- Chemicals
- 7
- With full pages
- 2
Scaffold SMILES
O=C(Nc1ccccc1)NC1N=C(c2ccccn2)c2ccccc2NC1=O
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
Netazepide
CAS 155488-25-8C28H30N6O3
![Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-Na(2)-(3-methylphenyl)- chemical structure, C28H29N5O3, CAS 155412-26-3](/s/OCWLXZANZZFWCX-UHFFFAOYSA-N.svg)
Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-Na(2)-(3-methylphenyl)-
CAS 155412-26-3C28H29N5O3
![1-(3-Dimethylamino-phenyl)-3-[(S)-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea chemical structure, C29H32N6O3, CAS 186145-37-9](/s/INMWFCCMIFVEPO-AREMUKBSSA-N.svg)
1-(3-Dimethylamino-phenyl)-3-[(S)-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea
CAS 186145-37-9C29H32N6O3
N-((3R)-1-tert-Butylcarbonylmethyl-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-dimethylaminophenyl)urea
CAS 155488-26-9C29H32N6O3
CCK-B Receptor Antagonist 1
CAS 168161-71-5C28H30N6O3
CCK-B Receptor Antagonist 2
CAS 155412-88-7C27H28N6O3
Ceclazepide
CAS 1801749-44-9C30H32N6O5
Related scaffolds
Same ring framework with different atoms or bond orders
