CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 28 atoms

269 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
269
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)NC1N=C(c2ccccc2)c2ccccc2NC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)NC1N=C(c2ccccc2)c2ccccc2NC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 269 chemicals

RSV604 racemate chemical structure, C22H17FN4O2, CAS 676128-62-4
RSV604 racemate
CAS 676128-62-4C22H17FN4O2
1-(2-Fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea chemical structure, C22H17FN4O2, CAS 676128-63-5
1-(2-Fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea
CAS 676128-63-5C22H17FN4O2
Urea, N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)-, (R)- chemical structure, C24H22N4O2, CAS 118101-09-0
Urea, N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)-, (R)-
CAS 118101-09-0C24H22N4O2
(3S)-1-Methyl-3-[3-(3-methylphenyl)ureido]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one chemical structure, C24H22N4O2, CAS 118101-08-9
(3S)-1-Methyl-3-[3-(3-methylphenyl)ureido]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
CAS 118101-08-9C24H22N4O2
(R)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-chlorophenyl)-urea chemical structure, C23H19ClN4O2, CAS 119486-83-8
(R)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-chlorophenyl)-urea
CAS 119486-83-8C23H19ClN4O2
1-(4-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H19ClN4O2, CAS 118018-41-0
1-(4-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 118018-41-0C23H19ClN4O2
1-(3-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H19ClN4O2, CAS 119487-12-6
1-(3-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 119487-12-6C23H19ClN4O2
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(2-nitro-phenyl)-urea chemical structure, C23H19N5O4, CAS 119486-96-3
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(2-nitro-phenyl)-urea
CAS 119486-96-3C23H19N5O4
1-(2,4-Dichlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H18Cl2N4O2, CAS 119487-09-1
1-(2,4-Dichlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 119487-09-1C23H18Cl2N4O2
1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea chemical structure, C23H19ClN4O2, CAS 118101-07-8
1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea
CAS 118101-07-8C23H19ClN4O2
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(3-nitro-phenyl)-urea chemical structure, C23H19N5O4, CAS 119487-11-5
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(3-nitro-phenyl)-urea
CAS 119487-11-5C23H19N5O4
1-(3,4-Dichlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H18Cl2N4O2, CAS 119506-62-6
1-(3,4-Dichlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 119506-62-6C23H18Cl2N4O2
1-(2-Fluorophenyl)-3-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H19FN4O2, CAS 885515-45-7
1-(2-Fluorophenyl)-3-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)urea
CAS 885515-45-7C23H19FN4O2
1-(2-Bromophenyl)-3-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H19BrN4O2, CAS 548749-22-0
1-(2-Bromophenyl)-3-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)urea
CAS 548749-22-0C23H19BrN4O2
1-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-(3-methoxyphenyl)urea chemical structure, C24H21FN4O3, CAS 119487-03-5
1-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-(3-methoxyphenyl)urea
CAS 119487-03-5C24H21FN4O3
1-(2-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C23H19ClN4O2, CAS 119487-07-9
1-(2-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 119487-07-9C23H19ClN4O2
RSV604 (R enantiomer) chemical structure, C22H17FN4O2, CAS 932108-20-8
RSV604 (R enantiomer)
CAS 932108-20-8C22H17FN4O2
1-(3-Cyano-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea chemical structure, C24H19N5O2, CAS 145878-00-8
1-(3-Cyano-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea
CAS 145878-00-8C24H19N5O2
1-(3,5-Dimethylphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C25H24N4O2, CAS 1048916-11-5
1-(3,5-Dimethylphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 1048916-11-5C25H24N4O2
RSV-604A benzenesulfonate chemical structure, C28H23FN4O5S, CAS 959391-59-4
RSV-604A benzenesulfonate
CAS 959391-59-4C28H23FN4O5S
1-(3-Amino-phenyl)-3-[(R)-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea chemical structure, C28H29N5O3, CAS 155412-78-5
1-(3-Amino-phenyl)-3-[(R)-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea
CAS 155412-78-5C28H29N5O3
1-(2,4-Dimethoxyphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C25H24N4O4, CAS 548749-12-8
1-(2,4-Dimethoxyphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 548749-12-8C25H24N4O4
1-(2,4-Dimethylphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea chemical structure, C25H24N4O2, CAS 1048916-01-3
1-(2,4-Dimethylphenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
CAS 1048916-01-3C25H24N4O2
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(3-trifluoromethyl-phenyl)-urea chemical structure, C24H19F3N4O2, CAS 1048916-06-8
1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(3-trifluoromethyl-phenyl)-urea
CAS 1048916-06-8C24H19F3N4O2