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Murcko scaffold

Ring system with 2 rings and 12 atoms

57 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
57
With full pages
9
Scaffold SMILES

c1nc(CN2CCCCC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(CN2CCCCC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

4-(Piperidin-1-ylmethyl)-1,3-thiazol-2-amine chemical structure, C9H15N3S, CAS 17386-10-6
4-(Piperidin-1-ylmethyl)-1,3-thiazol-2-amine
CAS 17386-10-6C9H15N3S
4-[(4-Methylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine chemical structure, C10H17N3S, CAS 792954-13-3
4-[(4-Methylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine
CAS 792954-13-3C10H17N3S
4-[(3-Methylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine chemical structure, C10H17N3S, CAS 855715-26-3
4-[(3-Methylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine
CAS 855715-26-3C10H17N3S
1-[(2-Methyl-1,3-thiazol-4-yl)methyl]piperidine chemical structure, C10H16N2S, CAS 17386-15-1
1-[(2-Methyl-1,3-thiazol-4-yl)methyl]piperidine
CAS 17386-15-1C10H16N2S
1-((2-Methyl-1,3-thiazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C11H16N2O2S, CAS 193538-32-8
1-((2-Methyl-1,3-thiazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 193538-32-8C11H16N2O2S
4-[(3,5-Dimethylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine chemical structure, C11H19N3S, CAS 929974-23-2
4-[(3,5-Dimethylpiperidin-1-yl)methyl]-1,3-thiazol-2-amine
CAS 929974-23-2C11H19N3S
4-(((3R,5S)-3,5-Dimethylpiperidin-1-yl)methyl)-1,3-thiazol-2-amine chemical structure, C11H19N3S, CAS 2824986-88-9
4-(((3R,5S)-3,5-Dimethylpiperidin-1-yl)methyl)-1,3-thiazol-2-amine
CAS 2824986-88-9C11H19N3S
1-[(2-Methyl-4-thiazolyl)methyl]-4-piperidinamine chemical structure, C10H17N3S, CAS 933698-05-6
1-[(2-Methyl-4-thiazolyl)methyl]-4-piperidinamine
CAS 933698-05-6C10H17N3S
(4-(Piperidin-1-ylmethyl)thiazol-2-yl)methanamine chemical structure, C10H17N3S, CAS 933689-75-9
(4-(Piperidin-1-ylmethyl)thiazol-2-yl)methanamine
CAS 933689-75-9C10H17N3S
(4-((4-Methylpiperidin-1-yl)methyl)thiazol-2-yl)methanamine chemical structure, C11H19N3S, CAS 1181583-49-2
(4-((4-Methylpiperidin-1-yl)methyl)thiazol-2-yl)methanamine
CAS 1181583-49-2C11H19N3S
1-((1,3-Thiazol-4-yl)methyl)piperidin-4-amine chemical structure, C9H15N3S, CAS 933760-12-4
1-((1,3-Thiazol-4-yl)methyl)piperidin-4-amine
CAS 933760-12-4C9H15N3S
1-[(2-Amino-4-thiazolyl)methyl]-N,N-dimethyl-4-piperidinamine chemical structure, C11H20N4S, CAS 1154930-36-5
1-[(2-Amino-4-thiazolyl)methyl]-N,N-dimethyl-4-piperidinamine
CAS 1154930-36-5C11H20N4S
1-((2-Propylthiazol-4-yl)methyl)piperidin-3-ol chemical structure, C12H20N2OS, CAS 1241294-99-4
1-((2-Propylthiazol-4-yl)methyl)piperidin-3-ol
CAS 1241294-99-4C12H20N2OS
(1-((2-Propylthiazol-4-yl)methyl)piperidin-4-yl)methanol chemical structure, C13H22N2OS, CAS 1241268-65-4
(1-((2-Propylthiazol-4-yl)methyl)piperidin-4-yl)methanol
CAS 1241268-65-4C13H22N2OS
tert-Butyl N-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-yl]carbamate chemical structure, C14H23N3O2S, CAS 1228837-31-7
tert-Butyl N-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-yl]carbamate
CAS 1228837-31-7C14H23N3O2S
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidine-4-carboxylic acid chemical structure, C10H15N3O2S, CAS 1225227-29-1
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidine-4-carboxylic acid
CAS 1225227-29-1C10H15N3O2S
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidine-3-carboxylic acid chemical structure, C10H15N3O2S, CAS 1225227-41-7
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidine-3-carboxylic acid
CAS 1225227-41-7C10H15N3O2S
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidin-4-ol chemical structure, C9H15N3OS, CAS 1225227-47-3
1-[(2-Amino-1,3-thiazol-4-yl)methyl]piperidin-4-ol
CAS 1225227-47-3C9H15N3OS
{1-[(2-Methyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}methanamine chemical structure, C11H19N3S, CAS 1249955-95-0
{1-[(2-Methyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}methanamine
CAS 1249955-95-0C11H19N3S
{1-[(2-Ethyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}methanamine chemical structure, C12H21N3S, CAS 1249171-13-8
{1-[(2-Ethyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}methanamine
CAS 1249171-13-8C12H21N3S
1-((2-Methylthiazol-4-yl)methyl)piperidin-4-ol chemical structure, C10H16N2OS, CAS 1247446-43-0
1-((2-Methylthiazol-4-yl)methyl)piperidin-4-ol
CAS 1247446-43-0C10H16N2OS
(1-((2-Methylthiazol-4-yl)methyl)piperidin-3-yl)methanol chemical structure, C11H18N2OS, CAS 1249345-52-5
(1-((2-Methylthiazol-4-yl)methyl)piperidin-3-yl)methanol
CAS 1249345-52-5C11H18N2OS
1-((2-Methylthiazol-4-yl)methyl)piperidin-3-ol chemical structure, C10H16N2OS, CAS 1249568-41-9
1-((2-Methylthiazol-4-yl)methyl)piperidin-3-ol
CAS 1249568-41-9C10H16N2OS
1-(Thiazol-4-ylmethyl)piperidin-3-ol chemical structure, C9H14N2OS, CAS 1250137-42-8
1-(Thiazol-4-ylmethyl)piperidin-3-ol
CAS 1250137-42-8C9H14N2OS