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Murcko scaffold

Ring system with 3 rings and 22 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
15
With full pages
2
Scaffold SMILES

c1ccc(C(CCCN2CCNCC2)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C(CCCN2CCNCC2)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

Amperozide chemical structure, C23H29F2N3O, CAS 75558-90-6
Amperozide
CAS 75558-90-6C23H29F2N3O
Amperozide hydrochloride chemical structure, C23H30ClF2N3O, CAS 75529-73-6
Amperozide hydrochloride
CAS 75529-73-6C23H30ClF2N3O
1-(4,4-Bis(4-fluorophenyl)butyl)piperazine chemical structure, C20H24F2N2, CAS 5631-35-6
1-(4,4-Bis(4-fluorophenyl)butyl)piperazine
CAS 5631-35-6C20H24F2N2
1-(4-(4-Fluorophenyl)-4-phenylbutyl)piperazine chemical structure, C20H25FN2, CAS 6263-54-3
1-(4-(4-Fluorophenyl)-4-phenylbutyl)piperazine
CAS 6263-54-3C20H25FN2
1-Piperazineethanol, 4-(4,4-bis(4-fluorophenyl)butyl)-, dihydrochloride chemical structure, C22H30Cl2F2N2O, CAS 5580-42-7
1-Piperazineethanol, 4-(4,4-bis(4-fluorophenyl)butyl)-, dihydrochloride
CAS 5580-42-7C22H30Cl2F2N2O
Piperazine, 1-(4,4-bis(p-fluorophenyl)butyl)-, dihydrochloride chemical structure, C20H26Cl2F2N2, CAS 30297-96-2
Piperazine, 1-(4,4-bis(p-fluorophenyl)butyl)-, dihydrochloride
CAS 30297-96-2C20H26Cl2F2N2
Piperazine, 1-(4,4-diphenylbutyl)-4-methyl-, dihydrochloride chemical structure, C21H30Cl2N2, CAS 37028-02-7
Piperazine, 1-(4,4-diphenylbutyl)-4-methyl-, dihydrochloride
CAS 37028-02-7C21H30Cl2N2
Piperazinium, 1-(2-(acetyloxy)ethyl)-4-(4,4-bis(4-fluorophenyl)butyl)-1,4-dimethyl-, diiodide chemical structure, C26H36F2I2N2O2, CAS 68351-17-7
Piperazinium, 1-(2-(acetyloxy)ethyl)-4-(4,4-bis(4-fluorophenyl)butyl)-1,4-dimethyl-, diiodide
CAS 68351-17-7C26H36F2I2N2O2
Phenol, 2-(4-(4-methyl-1-piperazinyl)-1-phenylbutyl)-, dihydrochloride chemical structure, C21H30Cl2N2O, CAS 129841-28-7
Phenol, 2-(4-(4-methyl-1-piperazinyl)-1-phenylbutyl)-, dihydrochloride
CAS 129841-28-7C21H30Cl2N2O
Phenol, 4-methoxy-2-(4-(4-methyl-1-piperazinyl)-1-phenylbutyl)-, dihydrochloride chemical structure, C22H32Cl2N2O2, CAS 129841-29-8
Phenol, 4-methoxy-2-(4-(4-methyl-1-piperazinyl)-1-phenylbutyl)-, dihydrochloride
CAS 129841-29-8C22H32Cl2N2O2
1-Piperazineethanol, 4-(4,4-bis(4-fluorophenyl)butyl)-, acetate (ester), (Z)-2-butenedioate (1:2) chemical structure, C32H38F2N2O10, CAS 68379-26-0
1-Piperazineethanol, 4-(4,4-bis(4-fluorophenyl)butyl)-, acetate (ester), (Z)-2-butenedioate (1:2)
CAS 68379-26-0C32H38F2N2O10
Amperozide dihydrochloride chemical structure, C23H31Cl2F2N3O, CAS 1307807-06-2
Amperozide dihydrochloride
CAS 1307807-06-2C23H31Cl2F2N3O
4-(4,4-Diphenylbutyl)piperazine-1-carboxamide chemical structure, C21H27N3O, CAS 144466-08-0
4-(4,4-Diphenylbutyl)piperazine-1-carboxamide
CAS 144466-08-0C21H27N3O
5-(4-Nitrosopiperazin-1-yl)-2,2-diphenylpentanenitrile chemical structure, C21H24N4O, CAS 1086393-92-1
5-(4-Nitrosopiperazin-1-yl)-2,2-diphenylpentanenitrile
CAS 1086393-92-1C21H24N4O
1-[4,4-Bis(4-methylphenyl)butyl]piperazine chemical structure, C22H30N2, CAS 5631-36-7
1-[4,4-Bis(4-methylphenyl)butyl]piperazine
CAS 5631-36-7C22H30N2