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Murcko scaffold

Ring system with 3 rings and 24 atoms

54 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
54
With full pages
11
Scaffold SMILES

O=S(=O)(NCC(c1ccccc1)N1CCNCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCC(c1ccccc1)N1CCNCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

2,5-Difluoro-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C20H25F2N3O2S, CAS 903254-12-6
2,5-Difluoro-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 903254-12-6C20H25F2N3O2S
4-Methoxy-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C21H29N3O3S, CAS 898432-04-7
4-Methoxy-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898432-04-7C21H29N3O3S
N-(2-(4-Methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C20H27N3O2S, CAS 898451-40-6
N-(2-(4-Methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898451-40-6C20H27N3O2S
4-Methyl-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C21H29N3O2S, CAS 898451-42-8
4-Methyl-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898451-42-8C21H29N3O2S
2,5-Difluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C20H25F2N3O3S, CAS 906150-39-8
2,5-Difluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 906150-39-8C20H25F2N3O3S
4-Fluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C20H26FN3O3S, CAS 898431-20-4
4-Fluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 898431-20-4C20H26FN3O3S
4-Bromo-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C20H26BrN3O3S, CAS 903253-56-5
4-Bromo-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 903253-56-5C20H26BrN3O3S
4-Chloro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C20H26ClN3O3S, CAS 903303-87-7
4-Chloro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 903303-87-7C20H26ClN3O3S
4-Methoxy-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide chemical structure, C22H31N3O4S, CAS 903343-35-1
4-Methoxy-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide
CAS 903343-35-1C22H31N3O4S
4-Fluoro-N-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]-2-methylbenzene-1-sulfonamide chemical structure, C21H28FN3O3S, CAS 903303-93-5
4-Fluoro-N-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]-2-methylbenzene-1-sulfonamide
CAS 903303-93-5C21H28FN3O3S
4-Fluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide chemical structure, C21H28FN3O3S, CAS 906150-42-3
4-Fluoro-N-(2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide
CAS 906150-42-3C21H28FN3O3S
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3,4-dimethoxybenzenesulfonamide chemical structure, C21H28FN3O4S, CAS 898451-30-4
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3,4-dimethoxybenzenesulfonamide
CAS 898451-30-4C21H28FN3O4S
4-Fluoro-N-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzene-1-sulfonamide chemical structure, C19H23F2N3O2S, CAS 906150-45-6
4-Fluoro-N-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzene-1-sulfonamide
CAS 906150-45-6C19H23F2N3O2S
N-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C19H24FN3O2S, CAS 903253-88-3
N-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 903253-88-3C19H24FN3O2S
4-Bromo-N-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C19H23BrFN3O2S, CAS 906150-46-7
4-Bromo-N-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 906150-46-7C19H23BrFN3O2S
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-4-methylbenzenesulfonamide chemical structure, C20H26FN3O2S, CAS 898431-96-4
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-4-methylbenzenesulfonamide
CAS 898431-96-4C20H26FN3O2S
4-Chloro-N-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C19H23ClFN3O2S, CAS 898451-32-6
4-Chloro-N-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 898451-32-6C19H23ClFN3O2S
N-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]-4-methoxybenzenesulfonamide chemical structure, C20H26FN3O3S, CAS 898431-98-6
N-[2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]-4-methoxybenzenesulfonamide
CAS 898431-98-6C20H26FN3O3S
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C21H28FN3O3S, CAS 903343-58-8
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide
CAS 903343-58-8C21H28FN3O3S
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-2,5-dimethoxybenzenesulfonamide chemical structure, C21H28FN3O4S, CAS 898451-36-0
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-2,5-dimethoxybenzenesulfonamide
CAS 898451-36-0C21H28FN3O4S
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-2-methoxy-5-methylbenzenesulfonamide chemical structure, C21H28FN3O3S, CAS 903304-25-6
N-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-2-methoxy-5-methylbenzenesulfonamide
CAS 903304-25-6C21H28FN3O3S
3,4-Dimethoxy-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C22H31N3O4S, CAS 898451-38-2
3,4-Dimethoxy-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898451-38-2C22H31N3O4S
4-Fluoro-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C20H26FN3O2S, CAS 898432-01-4
4-Fluoro-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898432-01-4C20H26FN3O2S
4-Bromo-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide chemical structure, C20H26BrN3O2S, CAS 898432-02-5
4-Bromo-N-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)benzenesulfonamide
CAS 898432-02-5C20H26BrN3O2S