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Murcko scaffold

Ring system with 3 rings and 22 atoms

81 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
81
With full pages
21
Scaffold SMILES

c1ccc(CNCC(c2ccccc2)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNCC(c2ccccc2)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 81 chemicals

3-(Benzylamino)-2,2-diphenylpropanoic acid chemical structure, C22H21NO2, CAS 7477-33-0
3-(Benzylamino)-2,2-diphenylpropanoic acid
CAS 7477-33-0C22H21NO2
2-(Benzylamino)-1,1-diphenyl-1-ethanol chemical structure, C21H21NO, CAS 58565-19-8
2-(Benzylamino)-1,1-diphenyl-1-ethanol
CAS 58565-19-8C21H21NO
2-(Benzylamino)-1-(4-methylphenyl)-1-phenylethanol chemical structure, C22H23NO, CAS 60916-61-2
2-(Benzylamino)-1-(4-methylphenyl)-1-phenylethanol
CAS 60916-61-2C22H23NO
2-[(4-Chlorobenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C21H20ClNO, CAS 306977-65-1
2-[(4-Chlorobenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 306977-65-1C21H20ClNO
2-[(3,4-Dichlorobenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C21H19Cl2NO, CAS 321432-73-9
2-[(3,4-Dichlorobenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 321432-73-9C21H19Cl2NO
2-[(3,4-Dimethoxybenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C23H25NO3, CAS 321432-74-0
2-[(3,4-Dimethoxybenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 321432-74-0C23H25NO3
2-(Benzylamino)-1,1-bis(4-chlorophenyl)ethanol chemical structure, C21H19Cl2NO, CAS 321432-76-2
2-(Benzylamino)-1,1-bis(4-chlorophenyl)ethanol
CAS 321432-76-2C21H19Cl2NO
1,1-Bis(4-chlorophenyl)-2-[(4-methylbenzyl)amino]-1-ethanol chemical structure, C22H21Cl2NO, CAS 321432-77-3
1,1-Bis(4-chlorophenyl)-2-[(4-methylbenzyl)amino]-1-ethanol
CAS 321432-77-3C22H21Cl2NO
1,1-Bis(4-chlorophenyl)-2-[(4-fluorobenzyl)amino]-1-ethanol chemical structure, C21H18Cl2FNO, CAS 321432-79-5
1,1-Bis(4-chlorophenyl)-2-[(4-fluorobenzyl)amino]-1-ethanol
CAS 321432-79-5C21H18Cl2FNO
1,1-Bis(4-chlorophenyl)-2-[(2-fluorobenzyl)amino]-1-ethanol chemical structure, C21H18Cl2FNO, CAS 321432-80-8
1,1-Bis(4-chlorophenyl)-2-[(2-fluorobenzyl)amino]-1-ethanol
CAS 321432-80-8C21H18Cl2FNO
1,1-Bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol chemical structure, C22H21Cl2NO2, CAS 321432-83-1
1,1-Bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol
CAS 321432-83-1C22H21Cl2NO2
1,1-Bis(4-chlorophenyl)-2-[(4-methoxybenzyl)amino]-1-ethanol chemical structure, C22H21Cl2NO2, CAS 321432-84-2
1,1-Bis(4-chlorophenyl)-2-[(4-methoxybenzyl)amino]-1-ethanol
CAS 321432-84-2C22H21Cl2NO2
1,1-Bis(4-chlorophenyl)-2-[(2-methoxybenzyl)amino]-1-ethanol chemical structure, C22H21Cl2NO2, CAS 321432-88-6
1,1-Bis(4-chlorophenyl)-2-[(2-methoxybenzyl)amino]-1-ethanol
CAS 321432-88-6C22H21Cl2NO2
1,1-Bis(4-chlorophenyl)-2-[(3,4-dimethoxybenzyl)amino]-1-ethanol chemical structure, C23H23Cl2NO3, CAS 321432-89-7
1,1-Bis(4-chlorophenyl)-2-[(3,4-dimethoxybenzyl)amino]-1-ethanol
CAS 321432-89-7C23H23Cl2NO3
2-[(4-Methylbenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C22H23NO, CAS 306977-66-2
2-[(4-Methylbenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 306977-66-2C22H23NO
2-[(4-Methoxybenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C22H23NO2, CAS 306977-67-3
2-[(4-Methoxybenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 306977-67-3C22H23NO2
N-(2-Chlorobenzyl)-2-hydroxy-2,2-diphenyl-1-ethanaminium chloride chemical structure, C21H21Cl2NO, CAS 321521-62-4
N-(2-Chlorobenzyl)-2-hydroxy-2,2-diphenyl-1-ethanaminium chloride
CAS 321521-62-4C21H21Cl2NO
N-(3-Chlorobenzyl)-2-hydroxy-2,2-diphenyl-1-ethanaminium chloride chemical structure, C21H21Cl2NO, CAS 321521-63-5
N-(3-Chlorobenzyl)-2-hydroxy-2,2-diphenyl-1-ethanaminium chloride
CAS 321521-63-5C21H21Cl2NO
2-[(4-Fluorobenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C21H20FNO, CAS 400077-12-5
2-[(4-Fluorobenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 400077-12-5C21H20FNO
2-[(2,4-Dichlorobenzyl)amino]-1,1-diphenyl-1-ethanol chemical structure, C21H19Cl2NO, CAS 306977-69-5
2-[(2,4-Dichlorobenzyl)amino]-1,1-diphenyl-1-ethanol
CAS 306977-69-5C21H19Cl2NO
N-(4-Chlorobenzyl)-2-(4-chlorophenyl)-2-hydroxy-2-phenyl-1-ethanaminium chloride chemical structure, C21H20Cl3NO, CAS 321521-64-6
N-(4-Chlorobenzyl)-2-(4-chlorophenyl)-2-hydroxy-2-phenyl-1-ethanaminium chloride
CAS 321521-64-6C21H20Cl3NO
2-(4-Chlorophenyl)-N-(3,4-dichlorobenzyl)-2-hydroxy-2-phenyl-1-ethanaminium chloride chemical structure, C21H19Cl4NO, CAS 321521-65-7
2-(4-Chlorophenyl)-N-(3,4-dichlorobenzyl)-2-hydroxy-2-phenyl-1-ethanaminium chloride
CAS 321521-65-7C21H19Cl4NO
1-(4-Chlorophenyl)-2-[(4-methylbenzyl)amino]-1-phenyl-1-ethanol chemical structure, C22H22ClNO, CAS 306977-70-8
1-(4-Chlorophenyl)-2-[(4-methylbenzyl)amino]-1-phenyl-1-ethanol
CAS 306977-70-8C22H22ClNO
1-(4-Chlorophenyl)-2-[(4-methoxybenzyl)amino]-1-phenyl-1-ethanol chemical structure, C22H22ClNO2, CAS 306977-76-4
1-(4-Chlorophenyl)-2-[(4-methoxybenzyl)amino]-1-phenyl-1-ethanol
CAS 306977-76-4C22H22ClNO2