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Murcko scaffold

Ring system with 5 rings and 30 atoms

60 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
60
With full pages
2
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

N-Fmoc-4-(4-fluorobenzyl)piperidine-4-carboxylic Acid chemical structure, C28H26FNO4, CAS 225240-60-8
N-Fmoc-4-(4-fluorobenzyl)piperidine-4-carboxylic Acid
CAS 225240-60-8C28H26FNO4
9H-Fluoren-9-ylmethyl 4-[(4-carbonochloridoylphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H26ClNO3, CAS 1419285-92-9
9H-Fluoren-9-ylmethyl 4-[(4-carbonochloridoylphenyl)methyl]piperidine-1-carboxylate
CAS 1419285-92-9C28H26ClNO3
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-phenylaceticacid chemical structure, C28H27NO4, CAS 864932-96-7
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-phenylaceticacid
CAS 864932-96-7C28H27NO4
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-3-phenylpropanoic acid chemical structure, C29H29NO4, CAS 2094360-58-2
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-3-phenylpropanoic acid
CAS 2094360-58-2C29H29NO4
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)methyl]benzoic acid chemical structure, C28H27NO4, CAS 2138133-75-0
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)methyl]benzoic acid
CAS 2138133-75-0C28H27NO4
3-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-4-yl)-3-(4-fluorophenyl)propanoic acid chemical structure, C29H28FNO4, CAS 2137546-39-3
3-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-4-yl)-3-(4-fluorophenyl)propanoic acid
CAS 2137546-39-3C29H28FNO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-(3-methylphenyl)acetic acid chemical structure, C29H29NO4, CAS 2580215-27-4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-(3-methylphenyl)acetic acid
CAS 2580215-27-4C29H29NO4
4-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)methyl]benzoic acid chemical structure, C28H27NO4, CAS 439811-15-1
4-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)methyl]benzoic acid
CAS 439811-15-1C28H27NO4
4-[(3,4-Dichlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C28H25Cl2NO4, CAS 2138192-62-6
4-[(3,4-Dichlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2138192-62-6C28H25Cl2NO4
4-[(4-Ethylphenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C30H31NO4, CAS 2138511-58-5
4-[(4-Ethylphenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2138511-58-5C30H31NO4
rac-(2R,4S)-4-Benzyl-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-2-carboxylic acid chemical structure, C28H27NO4, CAS 2803414-68-6
rac-(2R,4S)-4-Benzyl-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-2-carboxylic acid
CAS 2803414-68-6C28H27NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-[(3-fluorophenyl)methyl]piperidine-4-carboxylic acid chemical structure, C28H26FNO4, CAS 2357698-04-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-[(3-fluorophenyl)methyl]piperidine-4-carboxylic acid
CAS 2357698-04-3C28H26FNO4
4-Benzyl-1-(((9H-fluoren-9-yl)methoxy)carbonyl)piperidine-4-carboxylic acid chemical structure, C28H27NO4, CAS 2356097-84-0
4-Benzyl-1-(((9H-fluoren-9-yl)methoxy)carbonyl)piperidine-4-carboxylic acid
CAS 2356097-84-0C28H27NO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-(4-methylphenyl)acetic acid chemical structure, C29H29NO4, CAS 2639426-87-0
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-(4-methylphenyl)acetic acid
CAS 2639426-87-0C29H29NO4
4-[(3-Chlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C28H26ClNO4, CAS 2357910-44-0
4-[(3-Chlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2357910-44-0C28H26ClNO4
4-[(2-Chlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C28H26ClNO4, CAS 2359104-63-3
4-[(2-Chlorophenyl)methyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2359104-63-3C28H26ClNO4
(9H-Fluoren-9-yl)methyl 4-[hydroxy(2-methoxyphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H29NO4, CAS 2763984-39-8
(9H-Fluoren-9-yl)methyl 4-[hydroxy(2-methoxyphenyl)methyl]piperidine-1-carboxylate
CAS 2763984-39-8C28H29NO4
(9H-Fluoren-9-yl)methyl 4-{[2-(hydroxymethyl)phenyl]methyl}piperidine-1-carboxylate chemical structure, C28H29NO3, CAS 2763908-32-1
(9H-Fluoren-9-yl)methyl 4-{[2-(hydroxymethyl)phenyl]methyl}piperidine-1-carboxylate
CAS 2763908-32-1C28H29NO3
(9H-Fluoren-9-yl)methyl 4-[hydroxy(2-methylphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H29NO3, CAS 2764005-01-6
(9H-Fluoren-9-yl)methyl 4-[hydroxy(2-methylphenyl)methyl]piperidine-1-carboxylate
CAS 2764005-01-6C28H29NO3
(9H-Fluoren-9-yl)methyl 4-[(2,5-difluorophenyl)(hydroxy)methyl]piperidine-1-carboxylate chemical structure, C27H25F2NO3, CAS 2763902-74-3
(9H-Fluoren-9-yl)methyl 4-[(2,5-difluorophenyl)(hydroxy)methyl]piperidine-1-carboxylate
CAS 2763902-74-3C27H25F2NO3
(9H-Fluoren-9-yl)methyl 4-[(2-hydroxy-5-methoxyphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H29NO4, CAS 2764004-42-2
(9H-Fluoren-9-yl)methyl 4-[(2-hydroxy-5-methoxyphenyl)methyl]piperidine-1-carboxylate
CAS 2764004-42-2C28H29NO4
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-[(2-methoxyphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H29NO4, CAS 2764016-05-7
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-[(2-methoxyphenyl)methyl]piperidine-1-carboxylate
CAS 2764016-05-7C28H29NO4
(9H-Fluoren-9-yl)methyl 4-benzyl-4-(hydroxymethyl)piperidine-1-carboxylate chemical structure, C28H29NO3, CAS 2763984-85-4
(9H-Fluoren-9-yl)methyl 4-benzyl-4-(hydroxymethyl)piperidine-1-carboxylate
CAS 2763984-85-4C28H29NO3
(9H-Fluoren-9-yl)methyl 4-[hydroxy(4-methoxyphenyl)methyl]piperidine-1-carboxylate chemical structure, C28H29NO4, CAS 2763927-87-1
(9H-Fluoren-9-yl)methyl 4-[hydroxy(4-methoxyphenyl)methyl]piperidine-1-carboxylate
CAS 2763927-87-1C28H29NO4