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Murcko scaffold

Ring system with 3 rings and 17 atoms

44 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
44
With full pages
20
Scaffold SMILES

O=C(c1ccccc1)c1csc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1csc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

N-(3-Benzoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-chloroacetamide chemical structure, C17H16ClNO2S, CAS 40312-37-6
N-(3-Benzoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-chloroacetamide
CAS 40312-37-6C17H16ClNO2S
3-Benzoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C15H15NOS, CAS 4651-72-3
3-Benzoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 4651-72-3C15H15NOS
(2-Amino-4,5,6,7-tetrahydro-1-benzothien-3-yl)(4-methylphenyl)methanone chemical structure, C16H17NOS, CAS 247206-89-9
(2-Amino-4,5,6,7-tetrahydro-1-benzothien-3-yl)(4-methylphenyl)methanone
CAS 247206-89-9C16H17NOS
3-(4-Methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C16H17NO2S, CAS 40312-30-9
3-(4-Methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 40312-30-9C16H17NO2S
3-(4-Bromobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C15H14BrNOS, CAS 247206-87-7
3-(4-Bromobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 247206-87-7C15H14BrNOS
3-(4-Chlorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C15H14ClNOS, CAS 40312-34-3
3-(4-Chlorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 40312-34-3C15H14ClNOS
(2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)(2-chlorophenyl)methanone chemical structure, C15H14ClNOS, CAS 29462-26-8
(2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)(2-chlorophenyl)methanone
CAS 29462-26-8C15H14ClNOS
AK-660/12300001 chemical structure, C17H17NO2S, CAS 18774-43-1
AK-660/12300001
CAS 18774-43-1C17H17NO2S
2-Chloro-N-[3-(2-methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide chemical structure, C18H18ClNO3S, CAS 459825-43-5
2-Chloro-N-[3-(2-methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide
CAS 459825-43-5C18H18ClNO3S
2-Chloro-N-[3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide chemical structure, C18H18ClNO2S, CAS 565180-45-2
2-Chloro-N-[3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide
CAS 565180-45-2C18H18ClNO2S
(2-Amino-4,5,6,7-tetrahydro-1-benzothien-3-yl)(3-methylphenyl)methanone chemical structure, C16H17NOS, CAS 796067-53-3
(2-Amino-4,5,6,7-tetrahydro-1-benzothien-3-yl)(3-methylphenyl)methanone
CAS 796067-53-3C16H17NOS
N-[3-(4-tert-Butylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-chloroacetamide chemical structure, C21H24ClNO2S, CAS 792954-19-9
N-[3-(4-tert-Butylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-chloroacetamide
CAS 792954-19-9C21H24ClNO2S
3-(3,5-Dimethoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C17H19NO3S, CAS 793678-79-2
3-(3,5-Dimethoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-79-2C17H19NO3S
3-(3-Fluorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C15H14FNOS, CAS 399043-35-7
3-(3-Fluorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 399043-35-7C15H14FNOS
2-Chloro-N-[3-(4-ethoxybenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide chemical structure, C20H22ClNO3S, CAS 792954-21-3
2-Chloro-N-[3-(4-ethoxybenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide
CAS 792954-21-3C20H22ClNO3S
N-(3-(4-tert-Butylbenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-chloroacetamide chemical structure, C22H26ClNO2S, CAS 792954-17-7
N-(3-(4-tert-Butylbenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-chloroacetamide
CAS 792954-17-7C22H26ClNO2S
3-(4-Methoxybenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C17H19NO2S, CAS 793678-80-5
3-(4-Methoxybenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-80-5C17H19NO2S
3-(4-Bromobenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C16H16BrNOS, CAS 793678-82-7
3-(4-Bromobenzoyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-82-7C16H16BrNOS
(2-Amino-6-methyl-4,5,6,7-tetrahydro-1-benzothien-3-yl)(2,3-dimethoxyphenyl)methanone chemical structure, C18H21NO3S, CAS 793678-83-8
(2-Amino-6-methyl-4,5,6,7-tetrahydro-1-benzothien-3-yl)(2,3-dimethoxyphenyl)methanone
CAS 793678-83-8C18H21NO3S
6-tert-Butyl-3-(3-fluorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C19H22FNOS, CAS 793678-84-9
6-tert-Butyl-3-(3-fluorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-84-9C19H22FNOS
6-tert-Butyl-3-(3,5-dimethoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C21H27NO3S, CAS 793678-85-0
6-tert-Butyl-3-(3,5-dimethoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-85-0C21H27NO3S
6-tert-Butyl-3-(4-methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C20H25NO2S, CAS 793678-86-1
6-tert-Butyl-3-(4-methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793678-86-1C20H25NO2S
(2-Amino-6-methyl-4,5,6,7-tetrahydro-1-benzothien-3-yl)(3,5-dimethoxyphenyl)methanone chemical structure, C18H21NO3S, CAS 793716-17-3
(2-Amino-6-methyl-4,5,6,7-tetrahydro-1-benzothien-3-yl)(3,5-dimethoxyphenyl)methanone
CAS 793716-17-3C18H21NO3S
6-tert-Butyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine chemical structure, C20H25NOS, CAS 793716-16-2
6-tert-Butyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
CAS 793716-16-2C20H25NOS