Murcko scaffold
2'-Phenyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] scaffold
26 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 24
- Chemicals
- 26
- With full pages
- 5
Scaffold SMILES
c1ccc(C2=NN3C(C2)c2ccccc2OC32CCCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 26 of 26 chemicals
![2-(4-Chlorophenyl)spiro[1,10b-dihydropyrazolo[1,5-c][1,3]benzoxazine-5,1'-cyclohexane] chemical structure, C21H21ClN2O, CAS 301331-11-3](/s/RTIDSCZYDHHMNK-UHFFFAOYSA-N.svg)
2-(4-Chlorophenyl)spiro[1,10b-dihydropyrazolo[1,5-c][1,3]benzoxazine-5,1'-cyclohexane]
CAS 301331-11-3C21H21ClN2O
9-Chloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro(benzo(E)pyrazolo(1,5-C)(1,3)oxazine-5,1'-cyclohexane)
CAS 303059-74-7C22H23ClN2O2
![9-Bromo-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclohexane] chemical structure, C22H23BrN2O2, CAS 303060-87-9](/s/FNUZRTUZQWTLEY-UHFFFAOYSA-N.svg)
9-Bromo-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclohexane]
CAS 303060-87-9C22H23BrN2O2
![1-Methyl-2'-phenyl-1',10'b-dihydrospiro(cyclohexane-3,5'-pyrazolo[1,5-c][1,3]benzoxazine) chemical structure, C22H24N2O, CAS 351419-56-2](/s/NTDBRNJTVVMTAD-UHFFFAOYSA-N.svg)
1-Methyl-2'-phenyl-1',10'b-dihydrospiro(cyclohexane-3,5'-pyrazolo[1,5-c][1,3]benzoxazine)
CAS 351419-56-2C22H24N2O
![2-Chloro-14-ethyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 4'-cyclohexane] chemical structure, C23H25ClN2O, CAS 956369-60-1](/s/BFKBWIIQRJCRSU-UHFFFAOYSA-N.svg)
2-Chloro-14-ethyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 4'-cyclohexane]
CAS 956369-60-1C23H25ClN2O
![4-Ethyl-2'-(3-methoxyphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C24H28N2O2, CAS 956370-40-4](/s/JILOZHADADGTRS-UHFFFAOYSA-N.svg)
4-Ethyl-2'-(3-methoxyphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 956370-40-4C24H28N2O2
![9'-Bromo-2'-(4-methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C23H25BrN2O2, CAS 956370-24-4](/s/OMEZZWUWVCNFRC-UHFFFAOYSA-N.svg)
9'-Bromo-2'-(4-methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 956370-24-4C23H25BrN2O2
![2'-(4-Methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C23H26N2O2, CAS 638145-03-6](/s/PWCXADYVWDUXAJ-UHFFFAOYSA-N.svg)
2'-(4-Methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 638145-03-6C23H26N2O2
![7'-Methoxy-2'-(4-methoxyphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C23H26N2O3, CAS 371125-18-7](/s/WMGKBJPKUZMADQ-UHFFFAOYSA-N.svg)
7'-Methoxy-2'-(4-methoxyphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 371125-18-7C23H26N2O3
![2-Bromo-14-methyl-9-(4-methylphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane] chemical structure, C23H25BrN2O, CAS 956262-76-3](/s/DZSYBWLZCNYYNT-UHFFFAOYSA-N.svg)
2-Bromo-14-methyl-9-(4-methylphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane]
CAS 956262-76-3C23H25BrN2O
![9'-Chloro-4-methyl-2'-phenyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C22H23ClN2O, CAS 956206-29-4](/s/ZANPOYAXSSKGTP-UHFFFAOYSA-N.svg)
9'-Chloro-4-methyl-2'-phenyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 956206-29-4C22H23ClN2O
![2'-(4-Chlorophenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C22H23ClN2O2, CAS 371236-17-8](/s/MEHSIEASXOREMU-UHFFFAOYSA-N.svg)
2'-(4-Chlorophenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 371236-17-8C22H23ClN2O2
![9'-Methoxy-2'-(4-methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C24H28N2O3, CAS 957002-91-4](/s/HEEYBYCYVWVKMA-UHFFFAOYSA-N.svg)
9'-Methoxy-2'-(4-methoxyphenyl)-4-methyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 957002-91-4C24H28N2O3
![2'-(3,4-Dimethoxyphenyl)-1',10'b-dihydrospiro(cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine) chemical structure, C23H26N2O3, CAS 371202-54-9](/s/IGTAVZAPGLHBIZ-UHFFFAOYSA-N.svg)
2'-(3,4-Dimethoxyphenyl)-1',10'b-dihydrospiro(cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine)
CAS 371202-54-9C23H26N2O3
![2'-(3,4-Dimethoxyphenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C24H28N2O4, CAS 371237-07-9](/s/GFJZCDCWXPQGNY-UHFFFAOYSA-N.svg)
2'-(3,4-Dimethoxyphenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 371237-07-9C24H28N2O4
![2-Bromo-9-(4-chlorophenyl)-14-methylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane] chemical structure, C22H22BrClN2O, CAS 956778-53-3](/s/ZCCQDUWQCGXNAB-UHFFFAOYSA-N.svg)
2-Bromo-9-(4-chlorophenyl)-14-methylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane]
CAS 956778-53-3C22H22BrClN2O
![14-Methyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclo hexane] chemical structure, C22H24N2O, CAS 380872-10-6](/s/ACCMBSIBIMDLQG-UHFFFAOYSA-N.svg)
14-Methyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclo hexane]
CAS 380872-10-6C22H24N2O
![1-(2-Chloro-14-ethylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyc lohexane]-9-yl)-4-methoxybenzene chemical structure, C24H27ClN2O2, CAS 957002-85-6](/s/QOJPIQYNVLYOHE-UHFFFAOYSA-N.svg)
1-(2-Chloro-14-ethylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyc lohexane]-9-yl)-4-methoxybenzene
CAS 957002-85-6C24H27ClN2O2
![4-Methoxy-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclo hexane] chemical structure, C22H24N2O2, CAS 371234-56-9](/s/LSXYGERBKOCNMW-UHFFFAOYSA-N.svg)
4-Methoxy-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclo hexane]
CAS 371234-56-9C22H24N2O2
![2-Bromo-14-ethyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane] chemical structure, C23H25BrN2O, CAS 956369-97-4](/s/XUZQUSSXMMALQL-UHFFFAOYSA-N.svg)
2-Bromo-14-ethyl-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,4'-cyclohexane]
CAS 956369-97-4C23H25BrN2O
![4-tert-Butyl-2'-(2-chlorophenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C26H31ClN2O2, CAS 1023558-76-0](/s/LGTRJSDIFMJKMV-UHFFFAOYSA-N.svg)
4-tert-Butyl-2'-(2-chlorophenyl)-7'-methoxy-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 1023558-76-0C26H31ClN2O2
7,9-Dichloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro(benzo(E)pyrazolo(1,5-C)(1,3)oxazine-5,1'-cyclohexane)
CAS 303061-48-5C22H22Cl2N2O2
![2'-Phenyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C21H22N2O, CAS 140473-08-1](/s/KEGFGPIAIGHPHO-UHFFFAOYSA-N.svg)
2'-Phenyl-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 140473-08-1C21H22N2O
![4-Methyl-2'-(4-methylphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C23H26N2O, CAS 956781-27-4](/s/RLBDOZURNPDPPC-UHFFFAOYSA-N.svg)
4-Methyl-2'-(4-methylphenyl)-1',10b'-dihydrospiro[cyclohexane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 956781-27-4C23H26N2O
Related scaffolds
Same ring framework with different atoms or bond orders
