Murcko scaffold
Ring system with 5 rings and 32 atoms
92 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 92
- With full pages
- 63
Scaffold SMILES
O=C1C(=Cc2cn(-c3ccccc3)nc2-c2ccccc2)SC(=S)N1Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 92 chemicals
![(5Z)-3-[(4-Methoxyphenyl)methyl]-5-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C28H23N3O2S2, CAS 955964-95-1](/s/MERDFWDFTUAMTR-XYGWBWBKSA-N.svg)
(5Z)-3-[(4-Methoxyphenyl)methyl]-5-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 955964-95-1C28H23N3O2S2
![(5Z)-3-Benzyl-5-{[3-(4-methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C28H23N3O2S2, CAS 955896-02-3](/s/LSUMCSVVLNTYCJ-XYGWBWBKSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(4-methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 955896-02-3C28H23N3O2S2
![(5Z)-5-{[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C29H25N3O3S2, CAS 623935-79-5](/s/GOIRLBUVEFJCSJ-QQXSKIMKSA-N.svg)
(5Z)-5-{[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623935-79-5C29H25N3O3S2
![(5Z)-3-(4-Methylbenzyl)-5-({3-[3-methyl-4-(prop-2-en-1-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C31H27N3O2S2, CAS 955889-28-8](/s/VECNXIILPFICLH-VEILYXNESA-N.svg)
(5Z)-3-(4-Methylbenzyl)-5-({3-[3-methyl-4-(prop-2-en-1-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 955889-28-8C31H27N3O2S2
![(5Z)-3-(4-Methoxybenzyl)-5-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C28H23N3O3S2, CAS 623933-22-2](/s/DDJZEXNXNRKMOZ-XYGWBWBKSA-N.svg)
(5Z)-3-(4-Methoxybenzyl)-5-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one
CAS 623933-22-2C28H23N3O3S2
![(5Z)-3-Benzyl-5-{[3-(4-isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C30H27N3O2S2, CAS 955889-32-4](/s/HFJKZACRXPUQEU-PKAZHMFMSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(4-isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one
CAS 955889-32-4C30H27N3O2S2
(5Z)-5-((3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623934-81-6C29H25N3O3S2
![(5Z)-3-Benzyl-5-({3-[2-methyl-4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C31H29N3O2S2, CAS 956044-54-5](/s/ABOLCBBIOAYOQH-QRQIAZFYSA-N.svg)
(5Z)-3-Benzyl-5-({3-[2-methyl-4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 956044-54-5C31H29N3O2S2
![(5Z)-3-Benzyl-5-({3-[4-(ethylsulfanyl)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C28H23N3OS3, CAS 1009186-28-0](/s/PCWXHQDSSBZWGU-UQQQWYQISA-N.svg)
(5Z)-3-Benzyl-5-({3-[4-(ethylsulfanyl)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 1009186-28-0C28H23N3OS3
![(5Z)-3-Benzyl-5-({1-phenyl-3-[4-(propylsulfanyl)phenyl]-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C29H25N3OS3, CAS 1009434-99-4](/s/IALWAMDHXVDJLT-ITYLOYPMSA-N.svg)
(5Z)-3-Benzyl-5-({1-phenyl-3-[4-(propylsulfanyl)phenyl]-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 1009434-99-4C29H25N3OS3
![(5Z)-3-Benzyl-5-{[3-(3-chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C28H22ClN3O2S2, CAS 956684-03-0](/s/VOKDUFPKHLGYGW-XYGWBWBKSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(3-chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 956684-03-0C28H22ClN3O2S2
![(5Z)-3-Benzyl-5-{[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C26H18ClN3OS2, CAS 311810-02-3](/s/PNVCIVOCLRJBNJ-HAHDFKILSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 311810-02-3C26H18ClN3OS2
![(5Z)-3-Benzyl-5-{[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C26H18FN3OS2, CAS 312601-61-9](/s/XALGBALMECAJOX-HAHDFKILSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 312601-61-9C26H18FN3OS2
3-Benzyl-5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
CAS 374616-39-4C26H19N3OS2
![(5Z)-3-Benzyl-5-{[3-(3-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C28H23N3O2S2, CAS 1008883-59-7](/s/ZTRADBMYLGOQOB-UQQQWYQISA-N.svg)
(5Z)-3-Benzyl-5-{[3-(3-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 1008883-59-7C28H23N3O2S2
![(5Z)-3-Benzyl-5-{[3-(4-ethoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C29H25N3O2S2, CAS 955893-37-5](/s/CASGMHNBZIAYJA-ONUIUJJFSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(4-ethoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 955893-37-5C29H25N3O2S2
(5Z)-5-((3-(4-Methoxy-3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623934-75-8C28H22N4O4S2
(5Z)-3-Benzyl-5-((3-(4-isobutoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 623934-90-7C31H29N3O2S2
![(5Z)-5-[(1,3-Diphenyl-1H-pyrazol-4-yl)methylene]-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C27H21N3OS2, CAS 624723-11-1](/s/XOBXMDPWALOLCR-JLPGSUDCSA-N.svg)
(5Z)-5-[(1,3-Diphenyl-1H-pyrazol-4-yl)methylene]-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 624723-11-1C27H21N3OS2
(5Z)-5-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623935-61-5C27H20FN3OS2
![(5Z)-5-{[3-(4-Isopropoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C30H27N3O2S2, CAS 623934-72-5](/s/RFHLSAVGZWPLDA-PKAZHMFMSA-N.svg)
(5Z)-5-{[3-(4-Isopropoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623934-72-5C30H27N3O2S2
![(5Z)-3-Benzyl-5-({3-[2-methyl-4-(prop-2-en-1-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C30H25N3O2S2, CAS 955877-02-8](/s/MANKOFMTZUGLNE-IMRQLAEWSA-N.svg)
(5Z)-3-Benzyl-5-({3-[2-methyl-4-(prop-2-en-1-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 955877-02-8C30H25N3O2S2
![(5Z)-5-[(3-Mesityl-1-phenyl-1H-pyrazol-4-yl)methylene]-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C30H27N3OS2, CAS 623934-80-5](/s/MROXSKXPUPXVKN-QQXSKIMKSA-N.svg)
(5Z)-5-[(3-Mesityl-1-phenyl-1H-pyrazol-4-yl)methylene]-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS 623934-80-5C30H27N3OS2
![(5Z)-3-Benzyl-5-{[3-(2-methyl-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C30H27N3O2S2, CAS 955877-98-2](/s/QMSJJUXOMFSBNW-IMRQLAEWSA-N.svg)
(5Z)-3-Benzyl-5-{[3-(2-methyl-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 955877-98-2C30H27N3O2S2
- (5Z)-5-((3-(4-Ethoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-74-7C30H27N3O2S2
- (5Z)-5-((3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one623935-83-1C29H25N3O4S2
- (5Z)-5-((3-(4-(Allyloxy)phenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623933-21-1C30H25N3O2S2
- (5Z)-5-{[3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-82-7C29H25N3O2S2
- (5Z)-3-(4-Methylbenzyl)-5-((1-phenyl-3-(4-propoxyphenyl)-1H-pyrazol-4-yl)methylene)-2-thioxo-1,3-thiazolidin-4-one623935-35-3C30H27N3O2S2
- (5Z)-5-((3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-83-8C28H23N3O2S2
- (5Z)-5-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-77-0C27H20ClN3OS2
- (5Z)-5-{[3-(4-Isopropoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one623933-20-0C30H27N3O3S2
- (5Z)-3-(4-Methylbenzyl)-5-{[3-(3-methyl-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one623933-24-4C31H29N3O2S2
- (5Z)-5-((3-(4-Ethoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-73-6C30H27N3O3S2
- (5Z)-5-((3-Mesityl-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one623934-79-2C30H27N3O2S2
- (5Z)-5-{[3-(3-Chloro-4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one624724-31-8C28H22ClN3O2S2
- (5Z)-3-(4-Methylbenzyl)-5-({3-[3-methyl-4-(propan-2-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one850243-17-3C31H29N3O2S2
- (5Z)-3-Benzyl-5-({3-[2-methyl-4-(propan-2-yloxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one957047-62-0C30H27N3O2S2
- (5Z)-5-{[3-(4-Butoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(4-methylbenzyl)-2-thioxo-1,3-thiazolidin-4-one623935-28-4C31H29N3O2S2
- (5Z)-3-Benzyl-5-{[3-(3-fluoro-4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one623936-11-8C27H20FN3OS2
- (5Z)-3-(2-Chlorobenzyl)-5-((3-(3-fluoro-4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxo-1,3-thiazolidin-4-one623936-15-2C27H19ClFN3OS2
- (5Z)-3-(1-Phenylethyl)-5-{[1-phenyl-3-(3-propoxyphenyl)-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one1010870-75-3C30H27N3O2S2
- (5Z)-5-{[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(1-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one313273-32-4C27H20FN3OS2
- (5Z)-3-(1-Phenylethyl)-5-((1-phenyl-3-(4-propoxyphenyl)-1H-pyrazol-4-yl)methylene)-2-thioxo-1,3-thiazolidin-4-one381167-83-5C30H27N3O2S2
- (5Z)-5-((3-(3-Fluoro-4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(1-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one623940-33-0C28H22FN3OS2
- (5Z)-3-Benzyl-5-{[3-(4-ethoxy-3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one623935-95-5C28H22N4O4S2
- (5Z)-5-{[3-(4-Ethoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-3-(1-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one955867-61-5C30H27N3O2S2
- (5Z)-3-(2-Chlorobenzyl)-5-{[3-(3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one623935-82-0C28H22ClN3O3S2