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Murcko scaffold

Ring system with 3 rings and 29 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
18
With full pages
15
Scaffold SMILES

O=C(NN=Cc1cccc(OC(=O)c2ccccc2)c1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1cccc(OC(=O)c2ccccc2)c1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3-({2-[(2-Ethoxyanilino)(oxo)acetyl]hydrazinylidene}methyl)phenyl benzoate chemical structure, C24H21N3O5, CAS 6172-56-1
3-({2-[(2-Ethoxyanilino)(oxo)acetyl]hydrazinylidene}methyl)phenyl benzoate
CAS 6172-56-1C24H21N3O5
3-(2-((3-CL-4-Methylanilino)(oxo)AC)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H16Cl3N3O4, CAS 767305-65-7
3-(2-((3-CL-4-Methylanilino)(oxo)AC)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 767305-65-7C23H16Cl3N3O4
3-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C23H18ClN3O4, CAS 769152-79-6
3-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769152-79-6C23H18ClN3O4
3-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C23H18ClN3O5, CAS 767335-85-3
3-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 767335-85-3C23H18ClN3O5
3-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C22H16ClN3O4, CAS 769149-61-3
3-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769149-61-3C22H16ClN3O4
3-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O5, CAS 769156-36-7
3-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 769156-36-7C23H17Cl2N3O5
3-{(E)-[2-(2-Anilino-2-oxoacetyl)hydrazono]methyl}phenyl 2,4-dichlorobenzoate chemical structure, C22H15Cl2N3O4, CAS 769156-60-7
3-{(E)-[2-(2-Anilino-2-oxoacetyl)hydrazono]methyl}phenyl 2,4-dichlorobenzoate
CAS 769156-60-7C22H15Cl2N3O4
3-(2-((4-Bromoanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C22H15BrClN3O4, CAS 764655-63-2
3-(2-((4-Bromoanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 764655-63-2C22H15BrClN3O4
3-(2-((3,4-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C22H14Cl3N3O4, CAS 477732-06-2
3-(2-((3,4-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 477732-06-2C22H14Cl3N3O4
3-(2-((3-CL-2-Methylanilino)(oxo)AC)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C24H20ClN3O5, CAS 601499-70-1
3-(2-((3-CL-2-Methylanilino)(oxo)AC)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 601499-70-1C24H20ClN3O5
3-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O4, CAS 769153-44-8
3-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 769153-44-8C23H17Cl2N3O4
3-((E)-{2-[2-(4-Ethoxyanilino)-2-oxoacetyl]hydrazono}methyl)phenyl 4-methoxybenzoate chemical structure, C25H23N3O6, CAS 769154-19-0
3-((E)-{2-[2-(4-Ethoxyanilino)-2-oxoacetyl]hydrazono}methyl)phenyl 4-methoxybenzoate
CAS 769154-19-0C25H23N3O6
3-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C24H20ClN3O5, CAS 769151-00-0
3-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769151-00-0C24H20ClN3O5
3-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C24H20ClN3O4, CAS 764656-75-9
3-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 764656-75-9C24H20ClN3O4
3-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C24H19Cl2N3O5, CAS 767333-93-7
3-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 767333-93-7C24H19Cl2N3O5
3-(2-((4-Bromoanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C22H14BrCl2N3O4, CAS 767332-60-5
3-(2-((4-Bromoanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 767332-60-5C22H14BrCl2N3O4
3-(2-(Oxo(3-toluidino)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C24H21N3O5, CAS 765907-70-8
3-(2-(Oxo(3-toluidino)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 765907-70-8C24H21N3O5
3-(2-(Oxo(3-toluidino)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O4, CAS 765901-97-1
3-(2-(Oxo(3-toluidino)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 765901-97-1C23H17Cl2N3O4