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Murcko scaffold

Ring system with 3 rings and 27 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
21
With full pages
16
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1cccc(OCc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1cccc(OCc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-[(2-Bromo-5-phenylmethoxyphenyl)methylideneamino]-2-(4-methoxyphenoxy)acetamide chemical structure, C23H21BrN2O4, CAS 351202-25-0
N-[(2-Bromo-5-phenylmethoxyphenyl)methylideneamino]-2-(4-methoxyphenoxy)acetamide
CAS 351202-25-0C23H21BrN2O4
N'-(3-(Benzyloxy)benzylidene)-2-(2,4-dichlorophenoxy)acetohydrazide chemical structure, C22H18Cl2N2O3, CAS 349637-48-5
N'-(3-(Benzyloxy)benzylidene)-2-(2,4-dichlorophenoxy)acetohydrazide
CAS 349637-48-5C22H18Cl2N2O3
N'-{3-[(2-Chlorobenzyl)oxy]-4-methoxybenzylidene}-2-(4-chlorophenoxy)acetohydrazide chemical structure, C23H20Cl2N2O4, CAS 494759-45-4
N'-{3-[(2-Chlorobenzyl)oxy]-4-methoxybenzylidene}-2-(4-chlorophenoxy)acetohydrazide
CAS 494759-45-4C23H20Cl2N2O4
N'-(3-(Benzyloxy)benzylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 300673-64-7
N'-(3-(Benzyloxy)benzylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 300673-64-7C23H22N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-bromophenoxy)acetohydrazide chemical structure, C22H19BrN2O3, CAS 397304-09-5
N'-(3-(Benzyloxy)benzylidene)-2-(4-bromophenoxy)acetohydrazide
CAS 397304-09-5C22H19BrN2O3
N'-(3-(Benzyloxy)benzylidene)-2-(2,4-dichlorophenoxy)propanohydrazide chemical structure, C23H20Cl2N2O3, CAS 356106-32-6
N'-(3-(Benzyloxy)benzylidene)-2-(2,4-dichlorophenoxy)propanohydrazide
CAS 356106-32-6C23H20Cl2N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-isopropylphenoxy)acetohydrazide chemical structure, C25H26N2O3, CAS 403798-71-0
N'-(3-(Benzyloxy)benzylidene)-2-(4-isopropylphenoxy)acetohydrazide
CAS 403798-71-0C25H26N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-chlorophenoxy)acetohydrazide chemical structure, C22H19ClN2O3, CAS 341531-01-9
N'-(3-(Benzyloxy)benzylidene)-2-(4-chlorophenoxy)acetohydrazide
CAS 341531-01-9C22H19ClN2O3
N'-(3-(Benzyloxy)benzylidene)-2-phenoxyacetohydrazide chemical structure, C22H20N2O3, CAS 303132-11-8
N'-(3-(Benzyloxy)benzylidene)-2-phenoxyacetohydrazide
CAS 303132-11-8C22H20N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(2-methoxyphenoxy)acetohydrazide chemical structure, C23H22N2O4, CAS 468100-02-9
N'-(3-(Benzyloxy)benzylidene)-2-(2-methoxyphenoxy)acetohydrazide
CAS 468100-02-9C23H22N2O4
N'-(3-(Benzyloxy)benzylidene)-2-(4-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 328910-46-9
N'-(3-(Benzyloxy)benzylidene)-2-(4-methylphenoxy)acetohydrazide
CAS 328910-46-9C23H22N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(3-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 328910-39-0
N'-(3-(Benzyloxy)benzylidene)-2-(3-methylphenoxy)acetohydrazide
CAS 328910-39-0C23H22N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-fluorophenoxy)acetohydrazide chemical structure, C22H19FN2O3, CAS 395086-91-6
N'-(3-(Benzyloxy)benzylidene)-2-(4-fluorophenoxy)acetohydrazide
CAS 395086-91-6C22H19FN2O3
N'-(3-(Benzyloxy)benzylidene)-2-(3,4-dimethylphenoxy)acetohydrazide chemical structure, C24H24N2O3, CAS 463307-38-2
N'-(3-(Benzyloxy)benzylidene)-2-(3,4-dimethylphenoxy)acetohydrazide
CAS 463307-38-2C24H24N2O3
N'-{(E)-[3-(benzyloxy)phenyl]methylidene}-2-(3-chlorophenoxy)acetohydrazide chemical structure, C22H19ClN2O3, CAS 463307-39-3
N'-{(E)-[3-(benzyloxy)phenyl]methylidene}-2-(3-chlorophenoxy)acetohydrazide
CAS 463307-39-3C22H19ClN2O3
N'-(3-(Benzyloxy)benzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C26H28N2O3, CAS 765911-36-2
N'-(3-(Benzyloxy)benzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 765911-36-2C26H28N2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-bromophenoxy)propanohydrazide chemical structure, C23H21BrN2O3, CAS 881446-42-0
N'-(3-(Benzyloxy)benzylidene)-2-(4-bromophenoxy)propanohydrazide
CAS 881446-42-0C23H21BrN2O3
N'-(3-(Benzyloxy)benzylidene)-2-(4-chlorophenoxy)propanohydrazide chemical structure, C23H21ClN2O3, CAS 881466-03-1
N'-(3-(Benzyloxy)benzylidene)-2-(4-chlorophenoxy)propanohydrazide
CAS 881466-03-1C23H21ClN2O3
N'-(3-((4-Chlorobenzyl)oxy)benzylidene)-2-(2,4-dichlorophenoxy)propanohydrazide chemical structure, C23H19Cl3N2O3, CAS 880067-30-1
N'-(3-((4-Chlorobenzyl)oxy)benzylidene)-2-(2,4-dichlorophenoxy)propanohydrazide
CAS 880067-30-1C23H19Cl3N2O3
2-(2,4-Dichlorophenoxy)-N'-({3-[(2,6-dichlorophenyl)methoxy]phenyl}methylidene)acetohydrazide chemical structure, C22H16Cl4N2O3, CAS 478646-27-4
2-(2,4-Dichlorophenoxy)-N'-({3-[(2,6-dichlorophenyl)methoxy]phenyl}methylidene)acetohydrazide
CAS 478646-27-4C22H16Cl4N2O3
N'-({3-[(2,4-Dichlorophenyl)methoxy]phenyl}methylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C23H20Cl2N2O3, CAS 478677-95-1
N'-({3-[(2,4-Dichlorophenyl)methoxy]phenyl}methylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 478677-95-1C23H20Cl2N2O3