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Murcko scaffold

Ring system with 2 rings and 17 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
23
With full pages
8
Scaffold SMILES

O=C(Cc1cccs1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1cccs1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-[(2-Methoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide chemical structure, C14H14N2O2S, CAS 4847-09-0
N-[(2-Methoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide
CAS 4847-09-0C14H14N2O2S
N-[(E)-(5-Bromo-2-fluorophenyl)methylideneamino]-2-thiophen-2-ylacetamide chemical structure, C13H10BrFN2OS, CAS 315227-13-5
N-[(E)-(5-Bromo-2-fluorophenyl)methylideneamino]-2-thiophen-2-ylacetamide
CAS 315227-13-5C13H10BrFN2OS
N'-(4-Chloro-3-nitrobenzylidene)-2-(2-thienyl)acetohydrazide chemical structure, C13H10ClN3O3S, CAS 6068-61-7
N'-(4-Chloro-3-nitrobenzylidene)-2-(2-thienyl)acetohydrazide
CAS 6068-61-7C13H10ClN3O3S
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-2-(2-thienyl)acetohydrazide chemical structure, C15H17N3OS, CAS 307509-61-1
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-2-(2-thienyl)acetohydrazide
CAS 307509-61-1C15H17N3OS
N'-[(Z)-(3-Hydroxyphenyl)methylidene]-2-(thiophen-2-yl)acetohydrazide chemical structure, C13H12N2O2S, CAS 1616928-36-9
N'-[(Z)-(3-Hydroxyphenyl)methylidene]-2-(thiophen-2-yl)acetohydrazide
CAS 1616928-36-9C13H12N2O2S
2,6-Dimethoxy-4-{(E)-[(2-thienylacetyl)hydrazono]methyl}phenyl acetate chemical structure, C17H18N2O5S, CAS 314068-81-0
2,6-Dimethoxy-4-{(E)-[(2-thienylacetyl)hydrazono]methyl}phenyl acetate
CAS 314068-81-0C17H18N2O5S
N'-[(E)-(4-Bromophenyl)methylidene]-2-(thiophen-2-yl)acetohydrazide chemical structure, C13H11BrN2OS, CAS 1616928-20-1
N'-[(E)-(4-Bromophenyl)methylidene]-2-(thiophen-2-yl)acetohydrazide
CAS 1616928-20-1C13H11BrN2OS
2-(2-Thienyl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide chemical structure, C16H18N2O4S, CAS 314068-76-3
2-(2-Thienyl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide
CAS 314068-76-3C16H18N2O4S
2-(Thiophen-2-yl)-N'-[(E)-(2,4,5-trimethoxyphenyl)methylidene]acetohydrazide chemical structure, C16H18N2O4S, CAS 314068-80-9
2-(Thiophen-2-yl)-N'-[(E)-(2,4,5-trimethoxyphenyl)methylidene]acetohydrazide
CAS 314068-80-9C16H18N2O4S
N'-[(1Z)-1-(4-Bromophenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide chemical structure, C14H13BrN2OS, CAS 314069-10-8
N'-[(1Z)-1-(4-Bromophenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide
CAS 314069-10-8C14H13BrN2OS
N-[(E)-Benzylideneamino]-2-thiophen-2-ylacetamide chemical structure, C13H12N2OS, CAS 1616928-17-6
N-[(E)-Benzylideneamino]-2-thiophen-2-ylacetamide
CAS 1616928-17-6C13H12N2OS
N-[(E)-(4-Ethoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide chemical structure, C15H16N2O2S, CAS 314068-74-1
N-[(E)-(4-Ethoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide
CAS 314068-74-1C15H16N2O2S
N-[(E)-(3-Methylphenyl)methylideneamino]-2-thiophen-2-ylacetamide chemical structure, C14H14N2OS, CAS 315227-27-1
N-[(E)-(3-Methylphenyl)methylideneamino]-2-thiophen-2-ylacetamide
CAS 315227-27-1C14H14N2OS
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide chemical structure, C14H14N2O2S, CAS 1616928-34-7
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-thiophen-2-ylacetamide
CAS 1616928-34-7C14H14N2O2S
N'-[(1Z)-1-(4-Fluorophenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide chemical structure, C14H13FN2OS, CAS 315226-72-3
N'-[(1Z)-1-(4-Fluorophenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide
CAS 315226-72-3C14H13FN2OS
N-[(Z)-1-(3-Bromophenyl)ethylideneamino]-2-thiophen-2-ylacetamide chemical structure, C14H13BrN2OS, CAS 315226-74-5
N-[(Z)-1-(3-Bromophenyl)ethylideneamino]-2-thiophen-2-ylacetamide
CAS 315226-74-5C14H13BrN2OS
N'-(2-Hydroxy-3-methoxybenzylidene)-2-(2-thienyl)acetohydrazide chemical structure, C14H14N2O3S, CAS 1616928-44-9
N'-(2-Hydroxy-3-methoxybenzylidene)-2-(2-thienyl)acetohydrazide
CAS 1616928-44-9C14H14N2O3S
N'-{(Z)-[2-hydroxy-3-(prop-2-en-1-yl)phenyl]methylidene}-2-(thiophen-2-yl)acetohydrazide chemical structure, C16H16N2O2S, CAS 307509-65-5
N'-{(Z)-[2-hydroxy-3-(prop-2-en-1-yl)phenyl]methylidene}-2-(thiophen-2-yl)acetohydrazide
CAS 307509-65-5C16H16N2O2S
N'-[(1Z)-1-(2-Hydroxyphenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide chemical structure, C14H14N2O2S, CAS 315226-80-3
N'-[(1Z)-1-(2-Hydroxyphenyl)ethylidene]-2-(thiophen-2-yl)acetohydrazide
CAS 315226-80-3C14H14N2O2S
N'-(3-Bromo-4-hydroxy-5-methoxybenzylidene)-2-(2-thienyl)acetohydrazide chemical structure, C14H13BrN2O3S, CAS 315226-82-5
N'-(3-Bromo-4-hydroxy-5-methoxybenzylidene)-2-(2-thienyl)acetohydrazide
CAS 315226-82-5C14H13BrN2O3S
N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-2-(2-thienyl)acetohydrazide chemical structure, C13H11BrN2O2S, CAS 314068-75-2
N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-2-(2-thienyl)acetohydrazide
CAS 314068-75-2C13H11BrN2O2S
N'-(2-Hydroxybenzylidene)-2-(2-thienyl)acetohydrazide chemical structure, C13H12N2O2S, CAS 1616928-35-8
N'-(2-Hydroxybenzylidene)-2-(2-thienyl)acetohydrazide
CAS 1616928-35-8C13H12N2O2S
N'-[(E)-(3-Ethoxy-4-hydroxyphenyl)methylidene]-2-(2-thienyl)acetohydrazide chemical structure, C15H16N2O3S, CAS 314069-01-7
N'-[(E)-(3-Ethoxy-4-hydroxyphenyl)methylidene]-2-(2-thienyl)acetohydrazide
CAS 314069-01-7C15H16N2O3S