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Murcko scaffold

4-(Pyrrolidin-1-yl)quinoline scaffold

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
33
With full pages
3
Scaffold SMILES

c1ccc2c(N3CCCC3)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyrrolidin-1-yl)quinoline page
Murcko scaffold c1ccc2c(N3CCCC3)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

4-(2-Methyl-1-pyrrolidyl)-7-chloroquinoline chemical structure, C14H15ClN2, CAS 6281-58-9
4-(2-Methyl-1-pyrrolidyl)-7-chloroquinoline
CAS 6281-58-9C14H15ClN2
7-Chloro-4-(1-pyrrolidinyl)quinoline chemical structure, C13H13ClN2, CAS 353257-12-2
7-Chloro-4-(1-pyrrolidinyl)quinoline
CAS 353257-12-2C13H13ClN2
Ethyl 8-methyl-4-(1-pyrrolidinyl)-3-quinolinecarboxylate chemical structure, C17H20N2O2, CAS 478248-18-9
Ethyl 8-methyl-4-(1-pyrrolidinyl)-3-quinolinecarboxylate
CAS 478248-18-9C17H20N2O2
8-Nitro-4-pyrrolidin-1-ylquinoline chemical structure, C13H13N3O2, CAS 714279-17-1
8-Nitro-4-pyrrolidin-1-ylquinoline
CAS 714279-17-1C13H13N3O2
Ethyl 6-nitro-4-(1-pyrrolidinyl)-3-quinolinecarboxylate chemical structure, C16H17N3O4, CAS 478248-31-6
Ethyl 6-nitro-4-(1-pyrrolidinyl)-3-quinolinecarboxylate
CAS 478248-31-6C16H17N3O4
7-Iodo-2-methyl-4-pyrrolidin-1-yl-quinoline chemical structure, C14H15IN2, CAS 403850-66-8
7-Iodo-2-methyl-4-pyrrolidin-1-yl-quinoline
CAS 403850-66-8C14H15IN2
4-(Pyrrolidin-1-yl)quinoline chemical structure, C13H14N2, CAS 46384-61-6
4-(Pyrrolidin-1-yl)quinoline
CAS 46384-61-6C13H14N2
Butyl 6-bromo-4-(pyrrolidin-1-yl)quinoline-2-carboxylate chemical structure, C18H21BrN2O2, CAS 887589-79-9
Butyl 6-bromo-4-(pyrrolidin-1-yl)quinoline-2-carboxylate
CAS 887589-79-9C18H21BrN2O2
Methyl 6,8-difluoro-4-(pyrrolidin-1-yl)quinoline-2-carboxylate chemical structure, C15H14F2N2O2, CAS 887589-83-5
Methyl 6,8-difluoro-4-(pyrrolidin-1-yl)quinoline-2-carboxylate
CAS 887589-83-5C15H14F2N2O2
6-Methyl-4-(1-pyrrolidinyl)-3-quinolinecarboxylic acid chemical structure, C15H16N2O2, CAS 933747-25-2
6-Methyl-4-(1-pyrrolidinyl)-3-quinolinecarboxylic acid
CAS 933747-25-2C15H16N2O2
4-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid hydrochloride chemical structure, C14H15ClN2O2, CAS 1172884-04-6
4-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid hydrochloride
CAS 1172884-04-6C14H15ClN2O2
4-(Pyrrolidin-1-yl)-8-(trifluoromethyl)quinoline chemical structure, C14H13F3N2, CAS 1020253-07-9
4-(Pyrrolidin-1-yl)-8-(trifluoromethyl)quinoline
CAS 1020253-07-9C14H13F3N2
4-(Pyrrolidin-1-yl)quinoline-2-carbonitrile chemical structure, C14H13N3, CAS 1394838-92-6
4-(Pyrrolidin-1-yl)quinoline-2-carbonitrile
CAS 1394838-92-6C14H13N3
7-Methoxy-4-pyrrolidin-1-ylquinoline-3-carbonitrile chemical structure, C15H15N3O, CAS 1215340-76-3
7-Methoxy-4-pyrrolidin-1-ylquinoline-3-carbonitrile
CAS 1215340-76-3C15H15N3O
4-(2-Methyl-1-pyrrolidinyl)-3-quinolinecarbonitrile chemical structure, C15H15N3, CAS 1183655-02-8
4-(2-Methyl-1-pyrrolidinyl)-3-quinolinecarbonitrile
CAS 1183655-02-8C15H15N3
[1-(Quinolin-4-yl)pyrrolidin-2-yl]methanol chemical structure, C14H16N2O, CAS 1293138-42-7
[1-(Quinolin-4-yl)pyrrolidin-2-yl]methanol
CAS 1293138-42-7C14H16N2O
1-Quinolin-4-yl-pyrrolidin-3-ylamine chemical structure, C13H15N3, CAS 916663-94-0
1-Quinolin-4-yl-pyrrolidin-3-ylamine
CAS 916663-94-0C13H15N3
1-(Quinolin-4-yl)pyrrolidin-3-ol chemical structure, C13H14N2O, CAS 916663-95-1
1-(Quinolin-4-yl)pyrrolidin-3-ol
CAS 916663-95-1C13H14N2O
1-(Quinolin-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C14H14N2O2, CAS 1284613-81-5
1-(Quinolin-4-yl)pyrrolidine-3-carboxylic acid
CAS 1284613-81-5C14H14N2O2
[(s)-1-(6-Methoxy-quinolin-4-yl)-pyrrolidin-3-yl]-methylamine chemical structure, C15H19N3O, CAS 1072828-43-3
[(s)-1-(6-Methoxy-quinolin-4-yl)-pyrrolidin-3-yl]-methylamine
CAS 1072828-43-3C15H19N3O
4-((R)-3-Amino-pyrrolidin-1-yl)-quinoline-6-carbonitrile chemical structure, C14H14N4, CAS 1072828-45-5
4-((R)-3-Amino-pyrrolidin-1-yl)-quinoline-6-carbonitrile
CAS 1072828-45-5C14H14N4
(R)-1-(6-Fluoro-quinolin-4-yl)-pyrrolidin-3-ylamine chemical structure, C13H14FN3, CAS 1072828-44-4
(R)-1-(6-Fluoro-quinolin-4-yl)-pyrrolidin-3-ylamine
CAS 1072828-44-4C13H14FN3
4-Pyrrolidin-1-yl-2-(trifluoromethyl)quinoline-6-carboxylic acid chemical structure, C15H13F3N2O2, CAS 958332-64-4
4-Pyrrolidin-1-yl-2-(trifluoromethyl)quinoline-6-carboxylic acid
CAS 958332-64-4C15H13F3N2O2
(1-Quinolin-4-yl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester chemical structure, C18H23N3O2, CAS 916663-93-9
(1-Quinolin-4-yl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
CAS 916663-93-9C18H23N3O2