Murcko scaffold
N-(Pyrimidin-4-yl)benzenesulfonamide scaffold
112 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 112
- With full pages
- 27
Scaffold SMILES
O=S(=O)(Nc1ccncn1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 112 chemicals
Sulfadimethoxine
CAS 122-11-2C12H14N4O4S
Sulfamonomethoxine
CAS 1220-83-3C11H12N4O3S
Sulfisomidine
CAS 515-64-0C12H14N4O2S
Sulfadoxine
CAS 2447-57-6C12H14N4O4S
Sulfametomidine
CAS 3772-76-7C12H14N4O3S
Pyrimethamine, sulfadoxine
CAS 37338-39-9C24H27ClN8O4S
Sulfaclomide
CAS 4015-18-3C12H13ClN4O2S
N-(4-(((2,6-Dimethyl-4-pyrimidinyl)amino)sulfonyl)phenyl)acetamide
CAS 3163-31-3C14H16N4O3S
Primor
CAS 8076-37-7C26H32N8O6S
N(4)-Acetylsulfamonomethoxine
CAS 4049-01-8C13H14N4O4S
N4-Acetylsulfadoxine
CAS 5018-54-2C14H16N4O5S
Sodium N-(2,6-dimethyl-4-pyrimidinyl)sulphanilamidate
C12H14N4NaO2S+
Sulfanilamide, n(sup 1)-(5-bromo-2,6-dimethyl-4-pyrimidinyl)-, sodium salt
CAS 4015-19-4C12H13BrN4O2S
4-Amino-N-(5-fluoro-2-methoxypyrimidin-4-yl)benzenesulfonamide
CAS 2680-98-0C11H11FN4O3S
N4-Acetylsulfadimethoxine
CAS 555-25-9C14H16N4O5S
Formylsulfamethine
CAS 795-13-1C13H14N4O3S
4-Amino-N-(2-(methoxymethyl)-6-methyl-4-pyrimidinyl)benzenesulfonamide
CAS 3120-39-6C13H16N4O3S
Sulfamonomethoxine sodium
CAS 38006-08-5C11H11N4NaO3S
![N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}butanamide chemical structure, C16H20N4O3S, CAS 316128-58-2](/s/DFAXODGOMLTMJZ-UHFFFAOYSA-N.svg)
N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}butanamide
CAS 316128-58-2C16H20N4O3S
![Methyl {4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamate chemical structure, C14H16N4O6S, CAS 10132-09-9](/s/WPLIQPBJRRXRKP-UHFFFAOYSA-N.svg)
Methyl {4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamate
CAS 10132-09-9C14H16N4O6S
![N-[4-[(2,6-Dimethoxy-4-pyrimidinyl)sulfamoyl]phenyl]butanamide chemical structure, C16H20N4O5S, CAS 328027-03-8](/s/ZPBKBNZIECGLRQ-UHFFFAOYSA-N.svg)
N-[4-[(2,6-Dimethoxy-4-pyrimidinyl)sulfamoyl]phenyl]butanamide
CAS 328027-03-8C16H20N4O5S
![N-(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)-2,2-dimethylpropanamide chemical structure, C17H22N4O5S, CAS 289630-83-7](/s/ORPRTQGZPAEJOQ-UHFFFAOYSA-N.svg)
N-(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)-2,2-dimethylpropanamide
CAS 289630-83-7C17H22N4O5S
![N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-2-methoxyacetamide chemical structure, C15H18N4O4S, CAS 571154-40-0](/s/OBXYDFDMPBOMKM-UHFFFAOYSA-N.svg)
N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-2-methoxyacetamide
CAS 571154-40-0C15H18N4O4S
![N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-2-(2-methoxyethoxy)acetamide chemical structure, C17H22N4O5S, CAS 376621-94-2](/s/AEWWHBNMOGOQHH-UHFFFAOYSA-N.svg)
N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-2-(2-methoxyethoxy)acetamide
CAS 376621-94-2C17H22N4O5S
- 4-{[(Acetylamino)carbothioyl]amino}-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide712318-32-6C15H17N5O5S2
- N-(2,6-Dimethoxy-4-pyrimidinyl)-4-({[(3-methylbutanoyl)amino]carbothioyl}amino)benzenesulfonamide791792-06-8C18H23N5O5S2
- 3-[4-(2,6-Dimethoxy-pyrimidin-4-ylsulfamoyl)-phenylcarbamoyl]-acrylic acid ethyl ester304669-24-7C18H20N4O7S
- N-({4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamothioyl)-2,2-dimethylpropanamide817570-40-4C18H23N5O5S2
- N-(2,6-Dimethoxypyrimidin-4-yl)-4-thioureidobenzenesulfonamide728918-61-4C13H15N5O4S2
- 1-[4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl]-3-(3-methoxypropyl)thiourea892202-15-2C17H23N5O5S2
- Sulfamonometoxine N-methylglucamine salt53607-04-8C18H29N5O8S
- Acetamide, N-(4-((6-methoxy-2-methyl-4-pyrimidinyl)aminosulfonyl)phenyl)-13394-85-9C14H16N4O4S
- N-[4-(2,6-Dimethoxy-pyrimidin-4-ylsulfamoyl)-phenyl]-succinamic acid94672-50-1C16H18N4O7S
- Ethyl 3-({4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamoyl)propanoate356550-78-2C18H22N4O7S
- 2-Chloro-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]acetamide28439-15-8C14H15ClN4O3S
- Sulfisomidine sodium2462-17-1C12H13N4NaO2S
- 2-Bromo-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}hexanamide380467-37-8C18H23BrN4O3S
- 4-Amino-N-(5-methoxy-4-pyrimidinyl)benzenesulfonamide3973-92-0C11H12N4O3S
- Methyl 4-[({4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamothioyl)amino]-4-oxobutanoate500201-28-5C18H21N5O7S2
- 2-Cyano-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}acetamide573993-14-3C15H15N5O3S
- 4-Chloro-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide6529-18-6C12H12ClN3O2S
- Ro 04-6790202466-68-0C12H16N6O2S
- 4-((4-(((2,6-Dimethoxy-4-pyrimidinyl)amino)sulphonyl)phenyl)amino)-4-oxoisocrotonic acid30047-37-1C16H16N4O7S
- Benzenesulfonamide, 4-amino-N-(2-methoxy-4-pyrimidinyl)-3346-09-6C11H12N4O3S
- 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide mixt. with 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine55128-75-1C23H25ClN8O3S
- 4-tert-Butyl-N-(6-chloropyrimidin-4-yl)benzenesulfonamide169677-46-7C14H16ClN3O2S
- Ro 04-6790 dihydrochloride1197333-95-1C12H18Cl2N6O2S
- N-(6-Amino-2-methoxypyrimidin-4-yl)-4-nitrobenzenesulfonamide40041-58-5C11H11N5O5S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals