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Murcko scaffold

Ring system with 2 rings and 13 atoms

106 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
106
With full pages
8
Scaffold SMILES

c1ccc(OCc2cccs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCc2cccs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 106 chemicals

N-[5-Chloro-2-(thiophen-2-ylmethoxy)benzyl]-2-methylpropan-2-amine chemical structure, C16H20ClNOS, CAS 705269-11-0
N-[5-Chloro-2-(thiophen-2-ylmethoxy)benzyl]-2-methylpropan-2-amine
CAS 705269-11-0C16H20ClNOS
2-Methyl-N-[[2-(thiophen-2-ylmethoxy)phenyl]methyl]propan-2-amine chemical structure, C16H21NOS, CAS 692773-92-5
2-Methyl-N-[[2-(thiophen-2-ylmethoxy)phenyl]methyl]propan-2-amine
CAS 692773-92-5C16H21NOS
Methyl({[4-(thiophen-2-ylmethoxy)phenyl]methyl})amine chemical structure, C13H15NOS, CAS 869947-87-5
Methyl({[4-(thiophen-2-ylmethoxy)phenyl]methyl})amine
CAS 869947-87-5C13H15NOS
N-[[5-Bromo-2-(thiophen-2-ylmethoxy)phenyl]methyl]-2-methylpropan-2-amine chemical structure, C16H20BrNOS, CAS 774191-41-2
N-[[5-Bromo-2-(thiophen-2-ylmethoxy)phenyl]methyl]-2-methylpropan-2-amine
CAS 774191-41-2C16H20BrNOS
N-(tert-Butyl)-N-[3-methoxy-4-(2-thienylmethoxy)benzyl]amine chemical structure, C17H23NO2S, CAS 774191-39-8
N-(tert-Butyl)-N-[3-methoxy-4-(2-thienylmethoxy)benzyl]amine
CAS 774191-39-8C17H23NO2S
2-{[4-(2-Thienylmethoxy)benzyl]amino}ethanol chemical structure, C14H17NO2S, CAS 856437-39-3
2-{[4-(2-Thienylmethoxy)benzyl]amino}ethanol
CAS 856437-39-3C14H17NO2S
N-[[3-Bromo-5-methoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl]butan-1-amine chemical structure, C17H22BrNO2S, CAS 774193-10-1
N-[[3-Bromo-5-methoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl]butan-1-amine
CAS 774193-10-1C17H22BrNO2S
2-{[3-Bromo-5-ethoxy-4-(2-thienylmethoxy)benzyl]amino}ethanol chemical structure, C16H20BrNO3S, CAS 774192-76-6
2-{[3-Bromo-5-ethoxy-4-(2-thienylmethoxy)benzyl]amino}ethanol
CAS 774192-76-6C16H20BrNO3S
Ethyl({[3-methoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl})amine chemical structure, C15H19NO2S, CAS 852404-79-6
Ethyl({[3-methoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl})amine
CAS 852404-79-6C15H19NO2S
4-(Thiophen-2-ylmethoxy)-benzaldehyde chemical structure, C12H10O2S, CAS 176543-46-7
4-(Thiophen-2-ylmethoxy)-benzaldehyde
CAS 176543-46-7C12H10O2S
[4-(Thiophen-2-ylmethoxy)phenyl]methanol chemical structure, C12H12O2S, CAS 881447-91-2
[4-(Thiophen-2-ylmethoxy)phenyl]methanol
CAS 881447-91-2C12H12O2S
3-Ethoxy-4-(thiophen-2-ylmethoxy)benzaldehyde chemical structure, C14H14O3S, CAS 852399-80-5
3-Ethoxy-4-(thiophen-2-ylmethoxy)benzaldehyde
CAS 852399-80-5C14H14O3S
3-Methoxy-4-(thiophen-2-ylmethoxy)benzaldehyde chemical structure, C13H12O3S, CAS 838882-69-2
3-Methoxy-4-(thiophen-2-ylmethoxy)benzaldehyde
CAS 838882-69-2C13H12O3S
[3-Methoxy-4-(thiophen-2-ylmethoxy)phenyl]methanol chemical structure, C13H14O3S, CAS 838886-23-0
[3-Methoxy-4-(thiophen-2-ylmethoxy)phenyl]methanol
CAS 838886-23-0C13H14O3S
N'-[3-Methoxy-4-(thiophen-2-ylmethoxy)benzyl]-N,N-dimethylethane-1,2-diamine chemical structure, C17H24N2O2S, CAS 881454-41-7
N'-[3-Methoxy-4-(thiophen-2-ylmethoxy)benzyl]-N,N-dimethylethane-1,2-diamine
CAS 881454-41-7C17H24N2O2S
1-{[3-Chloro-5-methoxy-4-(2-thienylmethoxy)benzyl]amino}-2-propanol chemical structure, C16H20ClNO3S, CAS 880802-66-4
1-{[3-Chloro-5-methoxy-4-(2-thienylmethoxy)benzyl]amino}-2-propanol
CAS 880802-66-4C16H20ClNO3S
N-(1-Methylpropyl)-4-(2-thienylmethoxy)benzenemethanamine chemical structure, C16H21NOS, CAS 861433-24-1
N-(1-Methylpropyl)-4-(2-thienylmethoxy)benzenemethanamine
CAS 861433-24-1C16H21NOS
2-{[3-Methoxy-4-(thiophen-2-ylmethoxy)benzyl]amino}-2-methylpropan-1-ol chemical structure, C17H23NO3S, CAS 880802-57-3
2-{[3-Methoxy-4-(thiophen-2-ylmethoxy)benzyl]amino}-2-methylpropan-1-ol
CAS 880802-57-3C17H23NO3S
N-[[3-Ethoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl]ethanamine chemical structure, C16H21NO2S, CAS 851116-98-8
N-[[3-Ethoxy-4-(thiophen-2-ylmethoxy)phenyl]methyl]ethanamine
CAS 851116-98-8C16H21NO2S
N-Allyl-N-[3-methoxy-4-(2-thienylmethoxy)benzyl]amine chemical structure, C16H19NO2S, CAS 880814-31-3
N-Allyl-N-[3-methoxy-4-(2-thienylmethoxy)benzyl]amine
CAS 880814-31-3C16H19NO2S
2-Methoxy-N-[3-methoxy-4-(thiophen-2-ylmethoxy)benzyl]ethanamine chemical structure, C16H21NO3S, CAS 880814-36-8
2-Methoxy-N-[3-methoxy-4-(thiophen-2-ylmethoxy)benzyl]ethanamine
CAS 880814-36-8C16H21NO3S
3-(Thiophen-2-ylmethoxy)-benzaldehyde chemical structure, C12H10O2S, CAS 878433-08-0
3-(Thiophen-2-ylmethoxy)-benzaldehyde
CAS 878433-08-0C12H10O2S
(4E,6E)-7-[5-(3,4-Bis-hydroxymethyl-phenoxymethyl)-2-thienyl]-3-ethylnona-4,6-dien-3-ol chemical structure, C24H32O4S, CAS 341554-99-2
(4E,6E)-7-[5-(3,4-Bis-hydroxymethyl-phenoxymethyl)-2-thienyl]-3-ethylnona-4,6-dien-3-ol
CAS 341554-99-2C24H32O4S
2-((Thiophen-2-yl)methoxy)benzoic acid chemical structure, C12H10O3S, CAS 67443-52-1
2-((Thiophen-2-yl)methoxy)benzoic acid
CAS 67443-52-1C12H10O3S