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Murcko scaffold

4-Oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide scaffold

24 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
24
With full pages
5
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cc(=O)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide page
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cc(=O)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

4H-1-Benzopyran-2-carboxanilide, 6-chloro-4'-(4-methyl-2-pyrimidinylsulfamoyl)-4-oxo- chemical structure, C21H15ClN4O5S, CAS 27455-37-4
4H-1-Benzopyran-2-carboxanilide, 6-chloro-4'-(4-methyl-2-pyrimidinylsulfamoyl)-4-oxo-
CAS 27455-37-4C21H15ClN4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 307545-34-2
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 307545-34-2C22H18N4O5S
6-Chloro-7-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C22H17ClN4O5S, CAS 873082-05-4
6-Chloro-7-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 873082-05-4C22H17ClN4O5S
6-Chloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7-methyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H19ClN4O5S, CAS 890603-39-1
6-Chloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7-methyl-4-oxo-4H-chromene-2-carboxamide
CAS 890603-39-1C23H19ClN4O5S
6-Chloro-7-methyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C21H15ClN4O5S, CAS 898614-63-6
6-Chloro-7-methyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 898614-63-6C21H15ClN4O5S
6,8-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 873681-94-8
6,8-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 873681-94-8C22H18N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6,8-dimethyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C24H22N4O5S, CAS 896067-65-5
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6,8-dimethyl-4-oxo-4H-chromene-2-carboxamide
CAS 896067-65-5C24H22N4O5S
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C21H16N4O5S, CAS 333747-23-2
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 333747-23-2C21H16N4O5S
6-Methyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C21H16N4O5S, CAS 879568-19-1
6-Methyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 879568-19-1C21H16N4O5S
4-Oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C20H14N4O5S, CAS 879775-51-6
4-Oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 879775-51-6C20H14N4O5S
6-Methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 879565-77-2
6-Methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 879565-77-2C22H18N4O5S
6,7-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 880793-47-5
6,7-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 880793-47-5C22H18N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6-methyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 880793-74-8
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6-methyl-4-oxo-4H-chromene-2-carboxamide
CAS 880793-74-8C23H20N4O5S
6-Chloro-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C20H13ClN4O5S, CAS 880785-73-9
6-Chloro-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 880785-73-9C20H13ClN4O5S
7,8-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 873082-38-3
7,8-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 873082-38-3C22H18N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7,8-dimethyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C24H22N4O5S, CAS 874205-97-7
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7,8-dimethyl-4-oxo-4H-chromene-2-carboxamide
CAS 874205-97-7C24H22N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7-methyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 873081-32-4
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-7-methyl-4-oxo-4H-chromene-2-carboxamide
CAS 873081-32-4C23H20N4O5S
7,8-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 873082-44-1
7,8-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 873082-44-1C23H20N4O5S
6,7-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 873681-80-2
6,7-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 873681-80-2C23H20N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6-ethyl-4-oxo-4H-chromene-2-carboxamide chemical structure, C24H22N4O5S, CAS 874356-21-5
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-6-ethyl-4-oxo-4H-chromene-2-carboxamide
CAS 874356-21-5C24H22N4O5S
6-Ethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 874356-22-6
6-Ethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 874356-22-6C23H20N4O5S
5,7-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 898514-39-1
5,7-Dimethyl-4-oxo-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4H-chromene-2-carboxamide
CAS 898514-39-1C22H18N4O5S
5,7-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C23H20N4O5S, CAS 898486-12-9
5,7-Dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 898486-12-9C23H20N4O5S
7-Methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide chemical structure, C22H18N4O5S, CAS 898611-92-2
7-Methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-4-oxo-4H-chromene-2-carboxamide
CAS 898611-92-2C22H18N4O5S