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Murcko scaffold

Ring system with 4 rings and 30 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
14
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccccc1)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccccc1)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-{4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C22H22N2O6S2, CAS 440108-05-4
N-{4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 440108-05-4C22H22N2O6S2
N-[4-[(4-Bromophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C20H17BrN2O6S2, CAS 440098-44-2
N-[4-[(4-Bromophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 440098-44-2C20H17BrN2O6S2
N-{4-[(4-Methoxyphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H20N2O7S2, CAS 432498-04-9
N-{4-[(4-Methoxyphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 432498-04-9C21H20N2O7S2
N-{4-[(2-Methoxy-5-methylphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C22H22N2O7S2, CAS 431923-50-1
N-{4-[(2-Methoxy-5-methylphenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 431923-50-1C22H22N2O7S2
N-(4-(N-(2,4-Dimethylphenyl)sulfamoyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide chemical structure, C22H22N2O6S2, CAS 431979-61-2
N-(4-(N-(2,4-Dimethylphenyl)sulfamoyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide
CAS 431979-61-2C22H22N2O6S2
N-{4-[(4-Fluorophenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C20H17FN2O6S2, CAS 431927-96-7
N-{4-[(4-Fluorophenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 431927-96-7C20H17FN2O6S2
N-[4-[(2-Chlorophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C20H17ClN2O6S2, CAS 446042-52-0
N-[4-[(2-Chlorophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 446042-52-0C20H17ClN2O6S2
N-[4-[(4-Methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H20N2O6S2, CAS 585556-13-4
N-[4-[(4-Methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 585556-13-4C21H20N2O6S2
N-[4-[(2-Methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H20N2O6S2, CAS 446871-92-7
N-[4-[(2-Methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 446871-92-7C21H20N2O6S2
N-{4-[(3-Chlorophenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C20H17ClN2O6S2, CAS 462621-94-9
N-{4-[(3-Chlorophenyl)sulfamoyl]phenyl}-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 462621-94-9C20H17ClN2O6S2
N-[4-[(3-Chloro-4-methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H19ClN2O6S2, CAS 533918-76-2
N-[4-[(3-Chloro-4-methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 533918-76-2C21H19ClN2O6S2
N-[4-[(3-Chloro-2-methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H19ClN2O6S2, CAS 431978-83-5
N-[4-[(3-Chloro-2-methylphenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 431978-83-5C21H19ClN2O6S2
N-[4-[[3-(Trifluoromethyl)phenyl]sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C21H17F3N2O6S2, CAS 497225-13-5
N-[4-[[3-(Trifluoromethyl)phenyl]sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 497225-13-5C21H17F3N2O6S2
N-[4-[(4-Chlorophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide chemical structure, C20H17ClN2O6S2, CAS 432019-06-2
N-[4-[(4-Chlorophenyl)sulfamoyl]phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
CAS 432019-06-2C20H17ClN2O6S2