Murcko scaffold
Ring system with 4 rings and 28 atoms
81 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 28
- Chemicals
- 81
- With full pages
- 1
Scaffold SMILES
O=C(Nc1nc2ccccc2s1)c1ccc(S(=O)(=O)N2CCCCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 81 chemicals
![(E)-4-(Azepan-1-ylsulfonyl)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C21H23N3O3S2, CAS 850910-64-4](/s/WEKHQKQHMONUAF-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-64-4C21H23N3O3S2
4-(Azepan-1-ylsulfonyl)-N-(4-ethoxy-1,3-benzothiazol-2-yl)benzamide
CAS 501351-63-9C22H25N3O4S2
![(E)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H27N3O3S2, CAS 850909-04-5](/s/WPHJWZCVKZURCE-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850909-04-5C23H27N3O3S2
![(E)-Methyl 2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-3-methyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate chemical structure, C23H25N3O5S2, CAS 850909-17-0](/s/IVIOUJUOPREFPK-UHFFFAOYSA-N.svg)
(E)-Methyl 2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-3-methyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate
CAS 850909-17-0C23H25N3O5S2
![(E)-Ethyl 2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-3-methyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate chemical structure, C24H27N3O5S2, CAS 850909-41-0](/s/XNEKIAXVLCDFQW-UHFFFAOYSA-N.svg)
(E)-Ethyl 2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-3-methyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate
CAS 850909-41-0C24H27N3O5S2
4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-methoxy-1,3-benzothiazol-2-ylidene)benzamide
CAS 850909-69-2C23H27N3O4S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(6-ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C24H29N3O4S2, CAS 850909-90-9](/s/OJSLUDKLCIQHCH-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(6-ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850909-90-9C24H29N3O4S2
![(E)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H24FN3O3S2, CAS 850910-21-3](/s/IXKISKVLQRSRAD-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-21-3C22H24FN3O3S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H24N4O5S2, CAS 850910-56-4](/s/JMMQWACNUOTGOV-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-56-4C22H24N4O5S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H25N3O3S2, CAS 850910-75-7](/s/NWNYIUNZMCOKHC-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-75-7C22H25N3O3S2
![(E)-4-(Azepan-1-ylsulfonyl)-N-(3,4-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H25N3O3S2, CAS 850910-95-1](/s/NQDBNJDETICJMQ-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(3,4-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-95-1C22H25N3O3S2
![(E)-4-(Azepan-1-ylsulfonyl)-N-(4-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C21H22ClN3O3S2, CAS 850911-14-7](/s/FKOHQYUIPIHNKA-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(4-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850911-14-7C21H22ClN3O3S2
![(E)-4-(Azepan-1-ylsulfonyl)-N-(3,4,5-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H27N3O3S2, CAS 850911-36-3](/s/MDCXKDQUARPGHL-UHFFFAOYSA-N.svg)
(E)-4-(Azepan-1-ylsulfonyl)-N-(3,4,5-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850911-36-3C23H27N3O3S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-4-methoxybenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H27N3O4S2, CAS 533868-61-0](/s/HMJJKVUDFJZZAE-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-4-methoxybenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 533868-61-0C23H27N3O4S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(4-ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H27N3O4S2, CAS 533869-12-4](/s/MWICMKBKRKETDT-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(4-ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 533869-12-4C23H27N3O4S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(4-ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C24H29N3O4S2, CAS 533869-13-5](/s/QUYZDQRVUGJPCZ-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(4-ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 533869-13-5C24H29N3O4S2
4-(Azepan-1-ylsulfonyl)-N-(4,6-difluoro-3-methyl-1,3-benzothiazol-2-ylidene)benzamide
CAS 851079-83-9C21H21F2N3O3S2
4-(Azepan-1-ylsulfonyl)-N-(4-fluoro-1,3-benzothiazol-2-yl)benzamide
CAS 862807-22-5C20H20FN3O3S2
![4-(Azepan-1-ylsulfonyl)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)benzamide chemical structure, C21H23N3O5S3, CAS 681236-02-2](/s/QUUAJCSSNNRYLO-UHFFFAOYSA-N.svg)
4-(Azepan-1-ylsulfonyl)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)benzamide
CAS 681236-02-2C21H23N3O5S3
![(Z)-Ethyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate chemical structure, C24H28N4O7S3, CAS 865247-81-0](/s/WADQRMHZWHSJRG-UHFFFAOYSA-N.svg)
(Z)-Ethyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate
CAS 865247-81-0C24H28N4O7S3
![(Z)-Methyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-fluorobenzo[d]thiazol-3(2H)-yl)acetate chemical structure, C23H24FN3O5S2, CAS 865198-14-7](/s/GEVOZHIOGIHSPC-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-fluorobenzo[d]thiazol-3(2H)-yl)acetate
CAS 865198-14-7C23H24FN3O5S2
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-(2-ethoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C24H30N4O6S3, CAS 865173-90-6](/s/DNYCRMSGXHWNHV-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-(2-ethoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 865173-90-6C24H30N4O6S3
![(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-(2-methoxyethyl)-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C24H29N3O6S3, CAS 864977-12-8](/s/SNIBNFHAZJOUSH-UHFFFAOYSA-N.svg)
(Z)-4-(Azepan-1-ylsulfonyl)-N-(3-(2-methoxyethyl)-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 864977-12-8C24H29N3O6S3
![Methyl 2-[2-[4-(azepan-1-ylsulfonyl)benzoyl]imino-6-methoxy-1,3-benzothiazol-3-yl]acetate chemical structure, C24H27N3O6S2, CAS 865199-86-6](/s/JOFNYNKJIUWBME-UHFFFAOYSA-N.svg)
Methyl 2-[2-[4-(azepan-1-ylsulfonyl)benzoyl]imino-6-methoxy-1,3-benzothiazol-3-yl]acetate
CAS 865199-86-6C24H27N3O6S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(6-bromo-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)benzamide864976-02-3C23H26BrN3O4S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(4,7-dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide896676-52-1C23H27N3O5S2
- (Z)-Methyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate865198-83-0C23H26N4O7S3
- 4-(Azepan-1-ylsulfonyl)-N-(4,7-dimethoxybenzo[d]thiazol-2-yl)benzamide896676-35-0C22H25N3O5S2
- 4-(Azepan-1-ylsulfonyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)benzamide905690-74-6C20H19F2N3O3S2
- 4-(Azepan-1-ylsulfonyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)benzamide896676-12-3C22H25N3O4S2
- 4-(Azepan-1-ylsulfonyl)-N-(3,6-dimethyl-1,3-benzothiazol-2-ylidene)benzamide399000-27-2C22H25N3O3S2
- 4-(Azepan-1-ylsulfonyl)-N-(5,7-dimethylbenzo[d]thiazol-2-yl)benzamide896676-71-4C22H25N3O3S2
- (E)-4-(Azepan-1-ylsulfonyl)-N-(6-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide850782-06-8C22H25N3O4S2
- (Z)-Ethyl 2-(2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-6-methylbenzo[d]thiazol-3(2H)-yl)acetate865246-83-9C25H29N3O5S2
- Methyl 2-[2-[4-(azepan-1-ylsulfonyl)benzoyl]imino-6-methyl-1,3-benzothiazol-3-yl]acetate865197-33-7C24H27N3O5S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(6-chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide393835-14-8C21H22ClN3O3S2
- (E)-4-(Azepan-1-ylsulfonyl)-N-(6-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide399000-30-7C21H22FN3O3S2
- 4-(Azepan-1-ylsulfonyl)-N-(3-prop-2-ynyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)benzamide865182-13-4C23H24N4O5S3
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(6-fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)benzamide864976-45-4C23H26FN3O4S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(6-methoxy-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)benzamide1005988-94-2C24H29N3O5S2
- (E)-4-(Azepan-1-ylsulfonyl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide441291-45-8C22H25N3O4S2
- (Z)-Ethyl 2-((4-(azepan-1-ylsulfonyl)benzoyl)imino)-3-(2-methoxy-2-oxoethyl)-2,3-dihydrobenzo[d]thiazole-6-carboxylate897734-03-1C26H29N3O7S2
- 4-(Azepan-1-ylsulfonyl)-N-(7-chloro-4-methylbenzo[d]thiazol-2-yl)benzamide896675-89-1C21H22ClN3O3S2
- Methyl 2-[2-[4-(azepan-1-ylsulfonyl)benzoyl]imino-6-ethoxy-1,3-benzothiazol-3-yl]acetate941872-07-7C25H29N3O6S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(6-ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide443329-49-5C23H27N3O4S2
- (Z)-N-(3-Allyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-4-(azepan-1-ylsulfonyl)benzamide865175-56-0C24H27N3O5S3
- 4-(Azepan-1-ylsulfonyl)-N-(4,7-dimethylbenzo[d]thiazol-2-yl)benzamide896676-11-2C22H25N3O3S2
- (Z)-4-(Azepan-1-ylsulfonyl)-N-(3-ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide1007540-88-6C22H24FN3O3S2
Related scaffolds
Same ring framework with different atoms or bond orders
