Murcko scaffold
N-Benzylcyclobutanecarboxamide scaffold
36 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 36
- With full pages
- 3
Scaffold SMILES
O=C(NCc1ccccc1)C1CCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 36 of 36 chemicals
![Ethyl 3-methyl-1-[(R)-(1-phenylethyl)carbamoyl]-1-cyclobutanecarboxylate chemical structure, C17H23NO3, CAS 55649-63-3](/s/RTRZEVDKDPWDNW-UHFFFAOYSA-N.svg)
Ethyl 3-methyl-1-[(R)-(1-phenylethyl)carbamoyl]-1-cyclobutanecarboxylate
CAS 55649-63-3C17H23NO3
N-Benzylcyclobutanecarboxamide
CAS 15907-76-3C12H15NO
![N-[(1R)-1-(4-Bromophenyl)ethyl]cyclobutanecarboxamide chemical structure, C13H16BrNO, CAS 286442-93-1](/s/ZKVJJEODNIPOPE-SECBINFHSA-N.svg)
N-[(1R)-1-(4-Bromophenyl)ethyl]cyclobutanecarboxamide
CAS 286442-93-1C13H16BrNO
N-(2-Methoxybenzyl)cyclobutanecarboxamide
CAS 438537-81-6C13H17NO2
![N-[(4-Methylphenyl)methyl]cyclobutanecarboxamide chemical structure, C13H17NO, CAS 321865-46-7](/s/FVJNGJZXQYNASP-UHFFFAOYSA-N.svg)
N-[(4-Methylphenyl)methyl]cyclobutanecarboxamide
CAS 321865-46-7C13H17NO
![N-[1-(4-Bromophenyl)ethyl]cyclobutanecarboxamide chemical structure, C13H16BrNO, CAS 2459417-32-2](/s/ZKVJJEODNIPOPE-UHFFFAOYSA-N.svg)
N-[1-(4-Bromophenyl)ethyl]cyclobutanecarboxamide
CAS 2459417-32-2C13H16BrNO
![N-[1-(3,4-Dimethoxyphenyl)ethyl]cyclobutanecarboxamide chemical structure, C15H21NO3, CAS 894646-31-2](/s/KISHWLYCZQIPOV-UHFFFAOYSA-N.svg)
N-[1-(3,4-Dimethoxyphenyl)ethyl]cyclobutanecarboxamide
CAS 894646-31-2C15H21NO3
![N-[1-(2,5-Dimethylphenyl)ethyl]cyclobutanecarboxamide chemical structure, C15H21NO, CAS 894650-33-0](/s/DHXZZGVIEYYMEH-UHFFFAOYSA-N.svg)
N-[1-(2,5-Dimethylphenyl)ethyl]cyclobutanecarboxamide
CAS 894650-33-0C15H21NO
![N-[1-(3-Methoxyphenyl)ethyl]cyclobutanecarboxamide chemical structure, C14H19NO2, CAS 894654-30-9](/s/SMNHQEQOITXGKY-UHFFFAOYSA-N.svg)
N-[1-(3-Methoxyphenyl)ethyl]cyclobutanecarboxamide
CAS 894654-30-9C14H19NO2
![N-[1-(4-Ethylphenyl)ethyl]cyclobutanecarboxamide chemical structure, C15H21NO, CAS 894620-59-8](/s/HCTHQWFXUGFBQY-UHFFFAOYSA-N.svg)
N-[1-(4-Ethylphenyl)ethyl]cyclobutanecarboxamide
CAS 894620-59-8C15H21NO
![N-[1-(4-Methoxyphenyl)ethyl]cyclobutanecarboxamide chemical structure, C14H19NO2, CAS 894644-93-0](/s/TUWTWMRYCPSSOA-UHFFFAOYSA-N.svg)
N-[1-(4-Methoxyphenyl)ethyl]cyclobutanecarboxamide
CAS 894644-93-0C14H19NO2
3-(Cyclobutanecarboxamido)-3-phenylpropanoic acid
CAS 926253-26-1C14H17NO3
N-(3-Bromobenzyl)cyclobutanecarboxamide
CAS 925183-08-0C12H14BrNO
N-(3-Oxo-1-phenylpropyl)cyclobutanecarboxamide
CAS 277745-35-4C14H17NO2
N-(4-Methoxybenzyl)cyclobutanecarboxamide
CAS 1020804-06-1C13H17NO2
N-Benzyl-N-(2-hydroxyethyl)cyclobutanecarboxamide
CAS 1280831-59-5C14H19NO2
![N-[Cyano(3,4,5-trimethoxyphenyl)methyl]cyclobutanecarboxamide chemical structure, C16H20N2O4, CAS 1311638-51-3](/s/FZSVYUZGGAGDNZ-UHFFFAOYSA-N.svg)
N-[Cyano(3,4,5-trimethoxyphenyl)methyl]cyclobutanecarboxamide
CAS 1311638-51-3C16H20N2O4
![Cyclobutanecarboxylic acid, 1-[[[(4-cyanophenyl)methyl]amino]carbonyl]- chemical structure, C14H14N2O3, CAS 1271025-15-0](/s/ASACJHLWWMHMQS-UHFFFAOYSA-N.svg)
Cyclobutanecarboxylic acid, 1-[[[(4-cyanophenyl)methyl]amino]carbonyl]-
CAS 1271025-15-0C14H14N2O3
![N-[(1S)-3-Oxo-1-phenylbutyl]cyclobutanecarboxamide chemical structure, C15H19NO2, CAS 917807-05-7](/s/ODVKBBOLDYBANI-AWEZNQCLSA-N.svg)
N-[(1S)-3-Oxo-1-phenylbutyl]cyclobutanecarboxamide
CAS 917807-05-7C15H19NO2
4-((N-Methylcyclobutanecarboxamido)methyl)benzoic acid
CAS 1183649-61-7C14H17NO3
3-(Cyclobutanecarboxamidomethyl)benzoic acid
CAS 1179305-68-0C13H15NO3
1-Cyano-N-(3-methoxybenzyl)cyclobutane-1-carboxamide
CAS 1376332-19-2C14H16N2O2
N-(3-Bromobenzyl)-1-cyanocyclobutane-1-carboxamide
CAS 1486228-40-3C13H13BrN2O
![1-Cyano-N-[(4-methoxyphenyl)methyl]-3-methylcyclobutane-1-carboxamide chemical structure, C15H18N2O2, CAS 1516593-80-8](/s/UBKSUYTZLSYJJR-UHFFFAOYSA-N.svg)
1-Cyano-N-[(4-methoxyphenyl)methyl]-3-methylcyclobutane-1-carboxamide
CAS 1516593-80-8C15H18N2O2
- N-[(2-Chlorophenyl)-cyanomethyl]-1-methylsulfonylcyclobutane-1-carboxamide2189400-50-6C14H15ClN2O3S
- 3,3-Difluoro-N-[(2-methoxyphenyl)methyl]cyclobutane-1-carboxamide2324879-61-8C13H15F2NO2
- 3,3-Difluoro-N-[(4-methylphenyl)methyl]cyclobutane-1-carboxamide2327054-11-3C13H15F2NO
- 3,3-Difluoro-N-{[3-(trifluoromethyl)phenyl]methyl}cyclobutane-1-carboxamide2327211-02-7C13H12F5NO
- (3-(Cyclobutanecarboxamidomethyl)phenyl)boronic acid2246661-52-7C12H16BNO3
- N-{1-[3-(Aminomethyl)phenyl]ethyl}cyclobutanecarboxamide2137591-21-8C14H20N2O
- N-{[3-(1-Aminoethyl)phenyl]methyl}cyclobutanecarboxamide2137819-79-3C14H20N2O
- N-[2-(3-Bromophenyl)-1-hydroxypropan-2-yl]cyclobutanecarboxamide2137830-70-5C14H18BrNO2
- N-[(4-Cyano-2-methoxyphenyl)methyl]cyclobutanecarboxamide2138151-61-6C14H16N2O2
- N-[2-(4-Aminophenyl)propan-2-yl]cyclobutanecarboxamide2138229-20-4C14H20N2O
- N-[(3-Amino-2,6-dimethylphenyl)methyl]cyclobutanecarboxamide2137557-23-2C14H20N2O
- N-(3-Bromobenzyl)-1-methylcyclobutane-1-carboxamide2945735-06-6C13H16BrNO
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(OCc1ccccc1)N1CCC121 chemicals
c1ccc(COCC2COC2)cc15 chemicals
c1ccc(COCC2CCC2)cc14 chemicals
c1ccc(CNCC2CCC2)cc14 chemicals
O=C(OCc1ccccc1)C1CCC14 chemicals
c1ccc(COCC2CNC2)cc13 chemicals
O=C1CC(COCc2ccccc2)C12 chemicals
O=C1CN(C(=O)OCc2ccccc2)C12 chemicals
O=C(CC1CCC1)Nc1ccccc12 chemicals
O=C(CCc1ccccc1)N1CCC11 chemical
C1CNCC(CCCC2CNC2)C11 chemical
O=S(=O)(OCC1CCC1)c1ccccc11 chemical