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Murcko scaffold

Ring system with 2 rings and 14 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(CC1CCC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1CCC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Cyclobutyl-N-(4-methoxyphenyl)acetamide chemical structure, C13H17NO2, CAS 302567-76-6
2-Cyclobutyl-N-(4-methoxyphenyl)acetamide
CAS 302567-76-6C13H17NO2
2-Cyclobutyl-N-(4-iodophenyl)acetamide chemical structure, C12H14INO, CAS 310874-92-1
2-Cyclobutyl-N-(4-iodophenyl)acetamide
CAS 310874-92-1C12H14INO
2-Cyclobutyl-N-(2,4-dimethoxyphenyl)acetamide chemical structure, C14H19NO3, CAS 5924-66-3
2-Cyclobutyl-N-(2,4-dimethoxyphenyl)acetamide
CAS 5924-66-3C14H19NO3
N-(4-Acetylphenyl)-2-cyclobutylacetamide chemical structure, C14H17NO2, CAS 339116-59-5
N-(4-Acetylphenyl)-2-cyclobutylacetamide
CAS 339116-59-5C14H17NO2
4-(2-Cyclobutylacetamido)-3-nitrobenzene-1-sulfonyl chloride chemical structure, C12H13ClN2O5S, CAS 1977623-69-0
4-(2-Cyclobutylacetamido)-3-nitrobenzene-1-sulfonyl chloride
CAS 1977623-69-0C12H13ClN2O5S
1-[2-[(5-Chloro-2-methoxyphenyl)amino]-2-oxoethyl]cyclobutaneacetic acid chemical structure, C15H18ClNO4, CAS 1805818-84-1
1-[2-[(5-Chloro-2-methoxyphenyl)amino]-2-oxoethyl]cyclobutaneacetic acid
CAS 1805818-84-1C15H18ClNO4
N-[5-(2-Cyclobutyl-2-methylpropanamido)-2-fluorophenyl]prop-2-enamide chemical structure, C17H21FN2O2, CAS 2197450-26-1
N-[5-(2-Cyclobutyl-2-methylpropanamido)-2-fluorophenyl]prop-2-enamide
CAS 2197450-26-1C17H21FN2O2
N-{5-[2-(3,3-Difluorocyclobutyl)acetamido]-2-fluorophenyl}prop-2-enamide chemical structure, C15H15F3N2O2, CAS 2199413-73-3
N-{5-[2-(3,3-Difluorocyclobutyl)acetamido]-2-fluorophenyl}prop-2-enamide
CAS 2199413-73-3C15H15F3N2O2